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A cross-sectional study of urinary sodium, cardiac remodeling, and the mediating role of insulin-like growth factor-1: Insights from the UK Biobank. [PDF]

Medicine (Baltimore)
Yan D, Gao D, Yuan M.
europepmc   +1 more source

Umbilical cord serum insulin-like growth factor-1 is associated with growth of fetal fractional limb volume: A prospective study. [PDF]

Acta Obstet Gynecol Scand
Ikenoue S, Tamai J, Akita K, Otani T, Fukutake M, Kasuga Y, Tanaka M.   +6 more
europepmc   +1 more source

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Growth Hormone and Insulin-Like Growth Factor-1

2016
Human growth hormone (GH) was first isolated from the human pituitary gland in 1945 and found to promote the growth of children with hypopituitarism. Since the formation of the World Anti-Doping Association, human GH has appeared on the list of forbidden substances.
Nicholls, A.R., Holt, Richard
openaire   +3 more sources

Elevated insulin‐like growth factor‐1 in Cushing’s disease [PDF]

Clinical Endocrinology, 2019
SummaryObjectiveTo determine if patients with untreated Cushing's disease have higher serum insulin‐like growth factor‐1 (IGF‐1) compared to matched controls, and if IGF‐1 decreases following remission of Cushing's disease.DesignRetrospective case‐control study matching Cushing's disease cases to control patients for adenoma size, age, sex, diabetic ...
Katherine English, Viral Chikani, Goce Dimeski, Warrick J. Inder   +3 more
openaire   +4 more sources

Signaling by insulin-like growth factor 1 in brain

European Journal of Pharmacology, 2004
The homologous insulin and insulin-like growth factor (IGF) receptors are both expressed in the brain, in overlapping but distinct neuroanatomical patterns. In contrast to insulin, IGF1 is also highly expressed within the brain and is essential for normal brain development.
Carolyn A, Bondy, Clara M, Cheng
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Expression of insulin‐like growth factor 1 in sarcomas

Histopathology, 1990
The expression of insulin‐like growth factor‐1 (IGF‐1) was studied in normal tissues, in eight benign lesions and in 50 sarcomas. In palmar fibromatosis the spindle cells in cell‐dense areas exhibited a strong immunoreactivity. IGF‐1 was variably found in leiomyosarcomas (7/8), malignant schwannomas (7/9), synovial sarcomas (2/3), liposarcomas (3/6 ...
P J, Roholl, A, Skottner, I, Prinsen, C J, Lips, W, Den Otter, J A, Van Unnik   +5 more
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Expression of insulin-like growth factor-1 and insulin-like growth factor-1 receptors in EL4 lymphoma cells overexpressing growth hormone

Cellular Immunology, 2005
Almost all of the previous studies with growth hormone (GH) have been done with exogenously supplied GH and, therefore, involve actions of the hormone through its receptor. However, the actions of endogenous or lymphocyte GH are still unclear. In a previous study, we showed that overexpression of GH (GHo) in a lymphoid cell line resulted in protection ...
Douglas A, Weigent, Robyn E, Arnold
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The role of insulin-like growth factor-1 in lactation

Gene
Generally, Insulin-like growth factor 1 (IGF-1) is believed to regulate lactation activity by promoting cell proliferation and differentiation. With the advancement of research, IGF-1 has been discovered to play an important role in different stages of lactation.
Shuo, Zheng, Xi, Chen, JiaY, Fang, Yi, Li, XingY, Xiao, XunM, Zhang, LiB, Zhang, YunY, Cheng, LinL, Hao   +8 more
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Insulin-Like Growth Factor 1 Expression in Thyroid Tumors

Applied Immunohistochemistry & Molecular Morphology, 2000
Insulin-like growth factor 1 (IGF-1) likely is involved in thyrocyte proliferation via autocrine mechanisms, but limited data are available on its in vivo expression in thyroid neoplasms. This prompted us to explore IGF-1 expression at the protein and mRNA levels and IGF-1 receptor (IGF-1rec) immunoreactivity in normal and neoplastic thyroids (50 ...
Maiorano E, Ciampolillo A, Viale G, Maisonneuve P, Ambrosi A, Triggiani V, Marra E, Perlino E   +7 more
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