Results 271 to 280 of about 485,419 (310)

Insulin-Like Growth Factor 1 Expression in Thyroid Tumors

Applied Immunohistochemistry & Molecular Morphology, 2000
Insulin-like growth factor 1 (IGF-1) likely is involved in thyrocyte proliferation via autocrine mechanisms, but limited data are available on its in vivo expression in thyroid neoplasms. This prompted us to explore IGF-1 expression at the protein and mRNA levels and IGF-1 receptor (IGF-1rec) immunoreactivity in normal and neoplastic thyroids (50 ...
Maiorano E, Ciampolillo A, Viale G, Maisonneuve P, Ambrosi A, Triggiani V, Marra E, Perlino E   +7 more
openaire   +4 more sources

Alterations in insulin-like growth factor-1 gene and protein expression and type 1 insulin-like growth factor receptors in the brains of ageing rats

Neuroscience, 1999
Ageing in mammals is characterized by a decline in plasma levels of insulin-like growth factor-1 that appears to contribute to both structural and functional changes in a number of tissues.
W E Sonntag, C D Lynch, Rhonda L Ingram
exaly   +2 more sources

The role of insulin-like growth factor-1 in lactation

Gene
Generally, Insulin-like growth factor 1 (IGF-1) is believed to regulate lactation activity by promoting cell proliferation and differentiation. With the advancement of research, IGF-1 has been discovered to play an important role in different stages of lactation.
Shuo, Zheng, Xi, Chen, JiaY, Fang, Yi, Li, XingY, Xiao, XunM, Zhang, LiB, Zhang, YunY, Cheng, LinL, Hao   +8 more
openaire   +2 more sources

Insulin-like Growth Factor-1

2012
Strange, disturbing quality to subjects’ dream life. Difficulty concentrating. Headache in the forehead. Nasal congestion. Cramping abdominal pain associated with diarrhea or stool. Constipation with ineffectual urging. Strong uterine cramping with the menses. Premenstrual breast tenderness and swelling. Nausea. An aversion to chocolate and sweets.
openaire   +1 more source

Role of Insulin-like Growth Factor-1 in the Regulation of Skeletal Growth

Current Osteoporosis Reports, 2012
The importance of the insulin-like growth factor (IGF)-I axis in the regulation of bone size and bone mineral density, two important determinants of bone strength, has been well established from clinical studies involving patients with growth hormone deficiency and IGF-I gene disruption.
Subburaman, Mohan, Chandrasekhar, Kesavan   +1 more
openaire   +2 more sources

Insulin‐like growth factor 1 is essential for normal dendritic growth

Journal of Neuroscience Research, 2003
AbstractThis study evaluated somatic and dendritic growth of neurons in the frontoparietal cortex of Igf1–/– brains. Pyramidal neuron density was increased by ∼25% (P = .005) and soma size reduced by ∼10% (P < .001). Golgi staining revealed that cortical layer II–III neurons exhibited a significant reduction in dendritic length and complexity in ...
Clara M, Cheng, Ronald F, Mervis, Shui-Lin, Niu, Norman, Salem, Lee A, Witters, Victor, Tseng, Rickey, Reinhardt, Carolyn A, Bondy   +7 more
openaire   +2 more sources

Serum Levels of Insulin-like Growth Factor-1 and Insulin-like Growth Factor-1 Binding Proteins After Radical Prostatectomy

Journal of Urology, 2002
Elevated serum levels of insulin-like growth factor-1 (IGF-1) have been consistently shown to be a risk factor for prostate cancer. Alterations in serum IGF-1 binding proteins 1 to 3 have also been associated with prostate cancer risk. A potentially important complication in these studies is that prostate tissue, perhaps especially malignant prostate ...
Glenn J, Bubley, Steve P, Balk, Meredith M, Regan, Stephen, Duggan, Mary Ellen, Morrissey, William C, Dewolf, Ellena, Salgami, Christos, Mantzoros   +7 more
openaire   +2 more sources

Insulin-like Growth Factor-1 Deficiency

2019
Since insulin-like growth factor-1 (IGF-1) measurement has become widely known to reflect cumulative growth hormone (GH) secretion, it is not surprising for clinicians to be tempted to use IGF-1 levels to not only screen for GH excess but for GH deficiency also (Le Roith D. Seminars in medicine of the Beth Israel Deaconess Medical Center.
Thomas Ittoop, S. Sethu K. Reddy
openaire   +1 more source

Exercise and the Growth Hormone—Insulin-Like Growth Factor-1 Axis

2000
Naturally occurring physical activity in humans plays a profound role in tissue anabolism, growth, and development, yet little is known about the mechanisms that link patterns of exercise with tissue anabolism. Anabolic effects of exercise are not limited to individuals engaged in competitive sports who are particularly focused on improvements in ...
Alon Eliakim, Jo Anne Brasel, Dan M. Cooper   +2 more
openaire   +1 more source

The role of insulin - like growth factor - 1 on steatohepatitis.

Acta gastro-enterologica Belgica, 2017
Recent studies have revealed that growth hormone and STAT5 were related to hepatosteatosis in mice. Loss of signal transducer and activator of transcription factor-5 leads to hepatosteatosis and impaired liver regeneration. We aimed to investigate the role of IGF-1 in steatosis with normal (SNLFT) and disturbed liver function tests (SDLFT) in humans.We
Ata, Naim, Karadag, Ibrahim, Beyan, Esin, Ertugrul, Derun Taner, Unsal, OKTAY, Bulur, Oktay, Dal, Kursat, Yeniova, Abdullah Ozgur, Baser, Salih, Karakaya, Serdar, Dagdeviren, Murat   +10 more
openaire   +2 more sources