Results 261 to 270 of about 39,607,190 (300)

Insulin-Like Growth Factor 1 in the Cardiovascular System

2018
Non-communicable diseases, such as cardiovascular diseases, are the leading cause of mortality worldwide. For this reason, a tremendous effort is being made worldwide to effectively circumvent these afflictions, where insulin-like growth factor 1 (IGF1) is being proposed both as a marker and as a central cornerstone in these diseases, making it an ...
Gabriel A, Aguirre, José Luis, González-Guerra, Luis, Espinosa, Inma, Castilla-Cortazar   +3 more
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Insulin-like Growth Factor-1

2012
Strange, disturbing quality to subjects’ dream life. Difficulty concentrating. Headache in the forehead. Nasal congestion. Cramping abdominal pain associated with diarrhea or stool. Constipation with ineffectual urging. Strong uterine cramping with the menses. Premenstrual breast tenderness and swelling. Nausea. An aversion to chocolate and sweets.
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Role of Insulin-like Growth Factor-1 in the Regulation of Skeletal Growth

Current Osteoporosis Reports, 2012
The importance of the insulin-like growth factor (IGF)-I axis in the regulation of bone size and bone mineral density, two important determinants of bone strength, has been well established from clinical studies involving patients with growth hormone deficiency and IGF-I gene disruption.
Subburaman, Mohan, Chandrasekhar, Kesavan   +1 more
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The role of insulin - like growth factor - 1 on steatohepatitis.

Acta gastro-enterologica Belgica, 2017
Recent studies have revealed that growth hormone and STAT5 were related to hepatosteatosis in mice. Loss of signal transducer and activator of transcription factor-5 leads to hepatosteatosis and impaired liver regeneration. We aimed to investigate the role of IGF-1 in steatosis with normal (SNLFT) and disturbed liver function tests (SDLFT) in humans.We
Ata, Naim, Karadag, Ibrahim, Beyan, Esin, Ertugrul, Derun Taner, Unsal, OKTAY, Bulur, Oktay, Dal, Kursat, Yeniova, Abdullah Ozgur, Baser, Salih, Karakaya, Serdar, Dagdeviren, Murat   +10 more
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Insulin‐like growth factor 1 is essential for normal dendritic growth

Journal of Neuroscience Research, 2003
AbstractThis study evaluated somatic and dendritic growth of neurons in the frontoparietal cortex of Igf1–/– brains. Pyramidal neuron density was increased by ∼25% (P = .005) and soma size reduced by ∼10% (P < .001). Golgi staining revealed that cortical layer II–III neurons exhibited a significant reduction in dendritic length and complexity in ...
Clara M, Cheng, Ronald F, Mervis, Shui-Lin, Niu, Norman, Salem, Lee A, Witters, Victor, Tseng, Rickey, Reinhardt, Carolyn A, Bondy   +7 more
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Serum Levels of Insulin-like Growth Factor-1 and Insulin-like Growth Factor-1 Binding Proteins After Radical Prostatectomy

Journal of Urology, 2002
Elevated serum levels of insulin-like growth factor-1 (IGF-1) have been consistently shown to be a risk factor for prostate cancer. Alterations in serum IGF-1 binding proteins 1 to 3 have also been associated with prostate cancer risk. A potentially important complication in these studies is that prostate tissue, perhaps especially malignant prostate ...
Glenn J, Bubley, Steve P, Balk, Meredith M, Regan, Stephen, Duggan, Mary Ellen, Morrissey, William C, Dewolf, Ellena, Salgami, Christos, Mantzoros   +7 more
openaire   +2 more sources

Insulin-like Growth Factor-1 Deficiency

2019
Since insulin-like growth factor-1 (IGF-1) measurement has become widely known to reflect cumulative growth hormone (GH) secretion, it is not surprising for clinicians to be tempted to use IGF-1 levels to not only screen for GH excess but for GH deficiency also (Le Roith D. Seminars in medicine of the Beth Israel Deaconess Medical Center.
Thomas Ittoop, S. Sethu K. Reddy
openaire   +1 more source

Exercise and the Growth Hormone—Insulin-Like Growth Factor-1 Axis

2000
Naturally occurring physical activity in humans plays a profound role in tissue anabolism, growth, and development, yet little is known about the mechanisms that link patterns of exercise with tissue anabolism. Anabolic effects of exercise are not limited to individuals engaged in competitive sports who are particularly focused on improvements in ...
Alon Eliakim, Jo Anne Brasel, Dan M. Cooper   +2 more
openaire   +1 more source

Insulin‐Like Growth Factor‐1

Journal of the American Geriatrics Society, 2004
Colbert, L. H., Rosen, C., Goodpaster, B. H., Newman, A. B., Kritchevsky, S. B., Satterfield, S., Kanaya, A. M., Taaffe, D. R., Harris, T. B.   +8 more
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Insulin-Like Growth Factor-1 and Central Neurodegenerative Diseases

Endocrinology and Metabolism Clinics of North America, 2012
The previously undisputed neuroprotective role of insulin-like growth factor 1 (IGF-1) has been challenged by recent observations in IGF-1 receptor (IGF-1R) defective mutants. As new ligand-dependent and ligand-independent roles for IGF-1R are now emerging, new insights into the biologic role of brain IGF-1R and its connection with serum and brain IGF ...
openaire   +3 more sources