Results 281 to 290 of about 18,925,600 (331)
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Differential expression of insulin-like growth factor II in human meningiomas
Neurosurgery, 1991Two glioma tumor lines and brain tumor specimens from 10 patients were analyzed to determine genic expression of insulin-like growth factor II. Messenger ribonucleic acid encoding insulin-like growth factor II was found to be expressed in significant amounts in two of two meningiomas but not in any of the gliomas.
T, Lichtor, M A, Kurpakus, M E, Gurney
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Purification and characterization of insulin-like growth factor-II receptors
1989Publisher Summary This chapter discusses the purification and characterization of insulin-like growth factor-II (IGF-II) receptors. Successful purifications of IGF-II receptor to date have all employed IGF-II-agarose affinity chromatography. This technique has the advantage of being highly specific for the IGF-II receptor, resulting in high yields of
C D, Scott, R C, Baxter
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Expression of insulin-like growth factor-II transcripts in Wilms' tumour
Nature, 1985Wilms' tumour probably arises from embryonal kidney cells and occurs in both hereditary and sporadic forms. Knudson and Strong have suggested that both forms of the disease are initiated by two mutational events. In the case of the inherited form, cytogenetic evidence indicates that a germline deletion of chromosome band 11p13 may correspond to one of ...
A. Reeve +4 more
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The molecular and cellular biology of insulin-like growth factor II
Progress in Growth Factor Research, 1992Insulin-like growth factor II (IGF-II) is a 67 amino acid polypeptide that belongs to the family of insulin-like peptides. The IGF-II gene is coupled to the insulin gene and paternally imprinted. Multiple IGF-II mRNAs with identical coding regions and 3' untranslated regions (UTRs) but different 5' UTRs are generated from 3 promoters.
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Insulin-Like Growth Factor-II: Possible Local Growth Factor in Pheochromocytoma*
The Journal of Clinical Endocrinology & Metabolism, 1990Pheochromocytomas, neural crest tumors, express an abundance of insulin-like growth factor-II (IGF-II). To assess further the potential for IGF-II to play an autocrine role for these tumors, we measured 1) IGF-II content by RRA in 7 pheochromocytomas and peripheral blood in these patients, 2) IGF-II receptors by Western analysis, and 3) characterized ...
M C, Gelato, J, Vassalotti
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Regulation of Insulin-Like Growth Factor-II Production in Bone Cultures*
Endocrinology, 1991Although bone matrix is a rich source of insulin-like growth factor-II (IGF-II), little is known about the regulation of its synthesis by bone cells. This is due in part to the lack of simple and reliable assays to measure IGF-II. We have developed a method to dissociate IGF-II from its binding proteins by acidification and ultrafiltration, and ...
E, Canalis, M, Centrella, T L, McCarthy
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Insulin-like growth factor-II imprinting in cancer
The Lancet, 2002Anthony E, Reeve +3 more
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Insulin-like growth factor II receptor as a multifunctional binding protein
Nature, 1987David O. Morgan +6 more
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Biochemical and Biophysical Research Communications - BBRC, 2000
I. Xynos +4 more
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I. Xynos +4 more
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