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Glyoxal induces arterial injury through the inactivation of receptors and signaling pathways. [PDF]
Xie MZ +13 more
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Exerkines in precision management of metabolic diseases. [PDF]
Jin L +10 more
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, 1994
A 67 amino acid peptide, structurally similar to IGF-I (somatomedin C), but having greater insulin-like activity, and less growth promoting activity. Both IGF-I and IGF-II share structural similarities with proinsulin.
J. Seth
semanticscholar +2 more sources
A 67 amino acid peptide, structurally similar to IGF-I (somatomedin C), but having greater insulin-like activity, and less growth promoting activity. Both IGF-I and IGF-II share structural similarities with proinsulin.
J. Seth
semanticscholar +2 more sources
Primary structure of human insulin‐like growth factor II [PDF]
E. Rinderknecht, R. Humbel
semanticscholar +3 more sources
Parental imprinting of the mouse insulin-like growth factor II gene.
Cell, 1991We are studying mice that carry a targeted disruption of the gene encoding insulin-like growth factor II (IGF-II). Transmission of this mutation through the male germline results in heterozygous progeny that are growth deficient. In contrast, when the disrupted gene is transmitted maternally, the heterozygous offspring are phenotypically normal ...
T. Dechiara +2 more
semanticscholar +3 more sources
Synthetic insulin-like growth factor II
Biochemical and Biophysical Research Communications, 1985Human insulin-like growth factor II with 67 amino acid residues and three disulfide bridges has been synthesized by the solid-phase method. Homogeneity of the synthetic product is ascertained by chromatofocusing, high performance liquid chromatography and amino acid analysis.
C H, Li +3 more
openaire +2 more sources
Insulin‐Like Growth Factor II Effects Mediated through Insulin‐Like Growth Factor II Receptors
Acta Paediatrica, 1990ABSTRACT. Insulin‐like growth factor II (IGF‐II) resembles the homologous peptide insulin‐like growth factor I (IGF‐I) in that it stimulates cellular growth in vitro. This effect is generally believed to be mediated through IGF type 1 receptors; the role of the IGF type 2 receptor remains, as yet, unknown.
M, Tally, K, Hall
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Chemical synthesis of insulin‐like growth factor II
International Journal of Peptide and Protein Research, 1985Human insulin‐like growth factor II (IGF‐II) with 67 amino acids and three disulfide bridges has been synthesized by the solid‐phase method. The synthetic hormone is shown to be homogeneous in high performance liquid chromatography (HPLC), high performance partition chromatography (HPPC), and chromatofocusing.
D, Yamashiro, C H, Li
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Immunoreactive insulin-like growth factor II in urine
Acta Endocrinologica, 1990Abstract. Insulin-like growth factor II and insulin-like growth factor binding protein-1 were identified and quantified in the urine of 23 healthy subjects between 17 and 76 years of age. IGF-II was measured after separation by gel chromatography at low pH and compared with IGF-I levels in the same samples, whereas IGF binding protein-1 was measured in
W, Zumkeller, K, Hall
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