Results 231 to 240 of about 826,191 (386)

Lentropin, a protein that controls lens fiber formation, is related functionally and immunologically to the insulin-like growth factors.

, 1987
D. C. Beebe, M. H. Silver, K. S. Belcher, J. J. Van Wyk, M. E. Svoboda, P. S. Zelenka   +5 more
openalex   +2 more sources

SCORT–Cas13d Nanotherapy Precisely Targets the ‘Undruggable’ Transcription Factor HoxB13 in Metastatic Prostate Cancer In Vivo

Advanced Science, EarlyView.
SCORT–Cas13d–pre‐gHoxB13 lipid nanoparticles precisely deliver Cas13d mRNA and guide RNAs to metastatic prostate tumors in the liver, knocking down the “undruggable” transcription factor HoxB13. This approach suppresses metastatic tumor growth, extends mouse survival, and does not induce major organ toxicity or immune activation, offering a safe and ...
Zhifen Cui, Furong Huang, Kun Fang, Jingyue Yan, Yuebao Zhang, Diana D. Kang, Yufan Zhou, Yue Zhao, Jeffrey I. Everitt, William Hankey, Andrew J Armstrong, Jiaoti Huang, Hongyan Wang, Victor X. Jin, Yizhou Dong, Qianben Wang   +15 more
wiley   +1 more source

Insulin-like growth factor-1 (IGF-1) empowering tendon regenerative therapies. [PDF]

Front Bioeng Biotechnol
Wang M, Zhang J, Li H, Li Y, Li Z.
europepmc   +1 more source

Total synthesis of insulin-like growth factor I (somatomedin C). [PDF]

, 1983
C H Li, Darrell J. Yamashiro, Denis Gospodarowicz, Selna L. Kaplan, Guy Van Vliet   +4 more
openalex   +1 more source

Insulin-like growth factors and cancer [PDF]

British Journal of Cancer, 1992
openaire   +3 more sources

LncRNA‐MEG3 Regulates Muscle Mass and Metabolic Homeostasis by Facilitating SUZ12 Liquid–Liquid Phase Separation

Advanced Science, EarlyView.
This study has identified lncRNA‐MEG3 as a key regulator of muscle mass, promoting slow‐twitch muscle fibers and preventing muscle atrophy. By stabilizing the SUZ12/PRC2 complex through liquid–liquid phase separation (LLPS), lncRNA‐MEG3 influences mitochondrial function and lipid metabolism.
Yilong Yao, Chao Yan, Haibo Huang, Shilong Wang, Jiaying Li, Yun Chen, Xiaolu Qu, Qi Bao, Lingna Xu, Yuanyuan Zhang, Danyang Fan, Xia He, Yanwen Liu, Yongsheng Zhang, Yalan Yang, Zhonglin Tang   +15 more
wiley   +1 more source

Mediating effect of osteocalcin underlying the link between insulin-like growth factor-I and gestational diabetes mellitus. [PDF]

BMC Pregnancy Childbirth
Cui L, Gao Y, Sun R, Li Z, Zhang Z, Ji L, Wang Y, Ye H, Qin L.   +8 more
europepmc   +1 more source

Two insulin-like growth factor I messenger RNAs are expressed in human liver.

, 1986
Peter Rotwein
openalex   +1 more source

Nucleotides as an Anti‐Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study)

Advanced Science, EarlyView.
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang, Lixia Song, Rui Fan, Qianqian Chen, Ruisheng Fu, Mei You, Yuxiao Wu, Meng Cai, Yong Li, Meihong Xu   +9 more
wiley   +1 more source

The Role and Diagnostic Potential of Insulin-like Growth Factor 1 in Diabetic Retinopathy and Diabetic Macular Edema. [PDF]

Int J Mol Sci
Malepati A, Grant MB.
europepmc   +1 more source