Results 51 to 60 of about 826,191 (386)

Insulin-Like Growth Factor-I and Epidermal Growth Factor Regulate Insulin-Like Growth Factor Binding Protein-3 (IGFBP-3) in the Human Keratinocyte Cell Line HaCaT [PDF]

, 1995
The human keratinocyte cell line HaCaT has a basal phenotype and secretes an insulin-like growth factor (IGF) binding protein, IGFBP-3, which modulates its IGF-I response.
Werther, George A., Wraight, Christopher J.   +1 more
core   +1 more source

Surgical resection of a retroperitoneal liposarcoma producing insulin-like growth factor II: a case report

Surgical Case Reports, 2023
Background Tumor-produced high molecular weight insulin-like growth factor-II (big insulin-like growth factor-II) is considered to cause non-islet cell tumor hypoglycemia. This paper presents a case of surgically resected retroperitoneal liposarcoma that
Noriyuki Nishiwaki, Yoshihiro Mikuriya, Fumiaki Takatsu, Ryoji Ochiai, Tomokazu Kakishita, Naruyuki Kobayashi, Takaya Kobatake, Shinji Hato, Norihiro Teramoto, Mototsugu Nagao, Izumi Fukuda, Koji Ohta   +11 more
doaj   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

Associations among IGF-1, IGF2, IGF-1R, IGF-2R, IGFBP-3, insulin genetic polymorphisms and central precocious puberty in girls

BMC Endocrine Disorders, 2018
Background Insulin and insulin-like growth factor (IGF)-1 coupled with growth hormone helps control timing of sexual maturation. Mutations and variants in multiple genes are associated with development or reduced risk of central precocious puberty (CPP).
Hua-Pin Chang, Shun-Fa Yang, Shu-Li Wang, Pen-Hua Su   +3 more
doaj   +1 more source

A New Upper Bound For the Growth Factor in Gaussian Elimination with Complete Pivoting [PDF]

arXiv, 2023
The growth factor in Gaussian elimination measures how large the entries of an LU factorization can be relative to the entries of the original matrix. It is a key parameter in error estimates, and one of the most fundamental topics in numerical analysis. We produce an upper bound of $n^{0.2079 \ln n +0.91}$ for the growth factor in Gaussian elimination
arxiv  

Biomarkers of systemic inflammation and growth in early infancy are associated with stunting in young Tanzanian children [PDF]

, 2018
Stunting can afflict up to one-third of children in resource-constrained countries. We hypothesized that low-grade systemic inflammation (defined as elevations in serum C-reactive protein or alpha-1-acid glycoprotein) in infancy suppresses the growth ...
Aboud, Said, Duggan, Christopher P., Fawzi, Wafaie W., Kisenge, Rodrick, Liu, Enju, Locks, Lindsey, Manji, Karim P., McDonald, Christine M., Sudfeld, Christopher, Syed, Sana   +9 more
core   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

Growth factor parametrization in curved space [PDF]

Phys.Rev.D80:023002,2009, 2009
The growth rate of matter perturbation and the expansion rate of the Universe can be used to distinguish modified gravity and dark energy models in explaining cosmic acceleration. We explore here the inclusion of spatial curvature into the growth factor. We expand previous results using the approximation $\Omega_{m}^\gamma$ and then suggest a new form,
arxiv   +1 more source

Kinetics of urinary cell cycle arrest markers for acute kidney injury following exposure to potential renal insults [PDF]

, 2018
Objectives: Urinary tissue inhibitor of metalloproteinase-2 and insulin-like growth factor binding protein 7 predict the development of acute kidney injury following renal insults of varied aetiology.
Aliaga, Bellomo, Bihorac, Bonventre, Charlton, Emlet, Goldstein, Gunnerson, Honore, Hoste, Hoste, Jia, Joannidis, Kane-Gill, Kashani, Kaufman, Kerr, Lewington, McDonald, Meersch, Mehta, Mehta, Murrary, Peng, Perazella, Uchino, Waring, Wu   +27 more
core   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source