Dexamethasone Stimulates Transcription of the Insulin-Like Growth Factor-Binding Protein-1 Gene in H4-II-E Rat Hepatoma Cells [PDF]
Craig C. Orlowski+2 more
openalex +1 more source
Animal‐Free Setup of a 3D Mature Adipocyte‐Macrophage Co‐Culture to Induce Inflammation In Vitro
A completely animal‐free 3D co‐culture is developed using human fat cells and immune cells. Animal‐based materials are replaced with gellan gum hydrogel and a serum‐free medium. Immune cells are effectively activated, producing specific inflammatory signals.
Sophia Nowakowski+3 more
wiley +1 more source
Background and Objectives: We studied effects of eight weeks of resistance training and IGF-1 injection on serum level of IGF-1, IGFBP-3 and IGF-1/IGFBP-3 ratio in Wistar rats.
Babisan Askari+2 more
doaj
Effect of Insulin-Like Growth Factor-1 (IGF-1) on the expression of NFκB and cFLIP in Bovine Granulosa Cells [PDF]
Infertility, often attributed to follicular atresia, is a growing problem in the agricultural industry. Programmed cell death, also known as apoptosis, is a contributing factor of follicular atresia.
Docos, Samantha Kathleen
core +1 more source
Multifunctional Biomedical Devices with Closed‐Loop Systems for Precision Therapy
This review explores two major types of closed‐loop therapeutic systems: self‐sustained and externally triggered. It highlights recent advances in stimuli‐responsive materials, integrated bioelectronics, and data‐driven control strategies, offering insight into emerging strategies for personalized, responsive drug delivery.
Yixuan Leng, Rujie Sun
wiley +1 more source
Permeation Enhancer‐based Ionogel Shows Remarkable Potential for Oral Insulin Delivery
This study proposes a novel formulation of decanoate in an ionic liquid inspired drug delivery system. The formulation demonstrates ideal physicochemical and material properties for oral peptide delivery. Findings indicate that choline decanoate (1:2 molar ratio) forms a viscoelastic gel that enables high oral bioavailability of insulin in rats ...
Konstantinos Raptis+6 more
wiley +1 more source
Regulation of insulin-like growth factor-I (IGF-I) and IGF-binding protein 1 gene transcription by hormones and provision of amino acids in rat hepatocytes. [PDF]
C I Pao+6 more
openalex +1 more source
An ex vivo glomerular filtration barrier is engineered using electrospun, biomimetic membranes seeded with human glomerular cells. The model supports fenestrated endothelium and podocyte foot processes under flow, mimics size‐selective filtration, and enables disease modeling with hiPSC‐derived podocytes, offering a powerful platform for studying ...
Camilla Mussoni+8 more
wiley +1 more source
Insulin‐like growth factor 1 and dehydroepiandrosterone levels in alcoholic liver cirrhosis
Werner Dammermann+4 more
doaj +1 more source
Transcriptional Regulation of Rat Insulin-Like Growth Factor-Binding Protein-1 Expression by Growth Hormone [PDF]
Charita Seneviratne+2 more
openalex +1 more source