Results 241 to 250 of about 635,173 (353)

Emerging roles for insulin-like growth factor binding protein like protein 1

Neural Regeneration Research, 2019
Yingqian Li, Eric Zhao, Dong Feng Chen
doaj   +1 more source

Data of small molecule compounds and insulin-like growth factor-1 (IGF-1) detected in Deer Antler Velvet of Malayan Deer (<i>Cervus timorensis</i>). [PDF]

Data Brief
Mokhtar KI, Nordin NS, Mustafa BE, Ismail A, Abdullah MZ, Kenali NM, Zuberdi AM, Zainol I, Ahmad A.   +8 more
europepmc   +1 more source

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors

Advanced Science, EarlyView.
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen, Riya Gupta, Yosuke M. Morizawa, Yu Qin, Xingyu Du, Cynthia Pang, Osama Al‐Dalahmah, Maura B. Dupont, Guang Yang   +8 more
wiley   +1 more source

Evaluation of Serum Insulin-Like Growth Factor 1 (IGF-1) Among Controlled and Uncontrolled Type 2 Diabetes Mellitus in a Geriatric Population From North India. [PDF]

Cureus
Dev J A, Hussain S, Singh MK, Arif M, Sawlani KK, Usman K, Khattri S.   +6 more
europepmc   +1 more source

Insulin-like growth factor 1 receptor (IGF1R) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

ACSL5 Regulates Glucose Metabolism and Chemotherapy Sensitivity in Colorectal Cancer Cells under Glutamine Deficiency

Advanced Science, EarlyView.
Glutamine deprivation triggers ACSL5 upregulation in tumor cells, sustaining their viability via dual metabolic rewiring programs. ACSL5 enhances glycolysis by relieving p53's inhibition of PGAM1 while also sustaining mitochondrial respiration and TCA cycle flux through promoting IDH2 dimerization.
Shuai Tian, Qiaoxia Zhang, Xuedan Sun, Rick Francis Thorne, Zeyuan Shi, Qiang Ji, Zhangran Sun, Yuanxiang Lu, Qun Zhao, Xianjun Yu, Wanglai Hu, Mian Wu   +11 more
wiley   +1 more source

Roles of Insulin-Like Growth Factor-1 in Muscle Wasting and Osteopenia in Mice with Hyponatremia. [PDF]

Calcif Tissue Int
Kawao N, Nishikawa A, Matsumura D, Yamada A, Ohira T, Mizukami Y, Kaji H.   +6 more
europepmc   +1 more source

PSV-18 Relationships between serum insulin-like growth factor 1 and cortisol in growing steers to beef production and palatability [PDF]

Lauren T Wesolowski, Pier L Semanchik, Jessica L Simons, Chloey P Carson, A.N. DiSilvestro, Audrey L. Earnhardt-San, David R. Riley, George A. Perry, Charles R. Long, T.J. Machado, R.D. Randel, Thomas H. Welsh, Sarah H White-Springer   +12 more
openalex   +1 more source

RUNX2 Activation in Fibro/Adipogenic Progenitors Promotes Muscle Fibrosis in Muscular Dystrophy

Advanced Science, EarlyView.
This study revealed a novel role of the chemokine‐TGF‐β1‐RUNX2 axis in determining the fate of FAP differentiation and modulating muscle fibrosis in patients and mice with muscular dystrophies. ABSTRACT Clinical evidence indicates concurrent muscle inflammation and fibrosis in muscular dystrophies (MDs); however, the molecular mechanisms underlying ...
Pengkai Wu, Zehua Zhang, Kai Zheng, Ziqi Zhu, Yong Zhu, Abdukahar Kiram, Lei Zhao, Huihui Chen, Zhu Xu, Xihua Li, Beicheng Sun, Zhijian Li, Dengqiu Xu   +12 more
wiley   +1 more source

Association of insulin-like growth factor 1 and metabolic parameters with mild subclinical hypothyroidism in obese boys. [PDF]

Sci Rep
Xue J, Li C, Ju J, Liang S.
europepmc   +1 more source