Results 241 to 250 of about 714,864 (392)

Insulin-like growth factor-1 and risk of Alzheimer dementia and brain atrophy

Neurology, 2014
Andrew J. Westwood, A. Beiser, C. DeCarli, T. Harris, Tai-Chi Chen, Xuemei He, R. Roubenoff, A. Pikula, R. Au, L. Braverman, P. Wolf, R. Vasan, S. Seshadri   +12 more
semanticscholar   +1 more source

Hypoglycemia Induces Diabetic Macrovascular Endothelial Dysfunction via Endothelial Cell PANoptosis, Macrophage Polarization, and VSMC Fibrosis

Advanced Science, EarlyView.
This study investigates hypoglycemia‐induced diabetic macrovascular endothelial dysfunction. It reveals that hypoglycemia triggers ZBP1‐dependent PANoptosis of endothelial cells, proinflammatory polarization of macrophages, and fibrosis of vascular smooth muscle cells (VSMCs) in diabetic mice.
Deyu Zuo, Yuce Peng, Guozhi Zhao, Zhesheng Cheng, Minghao Luo, Dingyi Lv, Shuting Chang, Na Li, Yanyao Huang, Xunjia Li, An He   +10 more
wiley   +1 more source

Structure, Mechanics, and Mechanobiology of Fibrocartilage Pericellular Matrix Mediated by Type V Collagen

Advanced Science, EarlyView.
This study defines the structure, mechanics, and mechanobiology of the fibrocartilage pericellular matrix (PCM) using the murine meniscus, showing how collagen V deficiency alters PCM properties and disrupts cell mechanosensitive signaling. Findings emphasize the critical role of PCM in fibrocartilage mechanobiology and suggest targeting it can enhance
Chao Wang, Mingyue Fan, Su Chin Heo, Sheila M. Adams, Thomas Li, Yuchen Liu, Qing Li, Claudia Loebel, Jason A. Burdick, X. Lucas Lu, David E. Birk, Farid Alisafaei, Robert L. Mauck, Lin Han   +13 more
wiley   +1 more source

Predictive value of growth hormone and insulin-like growth factor-1 axis for gestational diabetes mellitus: a prospective cohort study. [PDF]

BMC Endocr Disord
Cui L, Wang Y, Li Z, Yang X, Zhou H, Zhang Z, Gao Y, Ji L, Sun R, Qin L.   +9 more
europepmc   +1 more source

Fluorescence-Based Multiplex Western Blot to Simultaneously Detect the Insulin-Like Growth Factor-1 (IGF-1) Isoforms. [PDF]

Electrophoresis
Bocconcelli M, Fanelli F, Saltarelli R, De Santi M, Barone R, Barbieri E, Annibalini G.   +6 more
europepmc   +1 more source

The NK₁ receptor and its participation in the synergistic enhancement of corneal epithelial migration by substance P and insulin‐like growth factor‐1 [PDF]

, 1997
Masatsugu Nakamura, Keiko Ofuji, Tai‐ichiro Chikama, Teruo Nishida   +3 more
openalex   +1 more source

Intranasal Insulin and Insulin-Like Growth Factor 1 as Neuroprotectants in Acute Ischemic Stroke

Translational Stroke Research, 2015
V. Lioutas, Freddy Alfaro-Martinez, Francisco Bedoya, Chen-Chih Chung, Daniela A. Pimentel, V. Novak   +5 more
semanticscholar   +1 more source

MCT1‐mediated Lactate Shuttle to Mitochondria Governs Macrophage Polarization and Modulates Glucose Homeostasis by Affecting β Cells

Advanced Science, EarlyView.
This study demonstrates that the transport of lactate to the mitochondria is of critical importance in determining the functions of macrophages by altering mitochondrial respiration. In macrophages, this lactate transport mechanism regulates glucose homeostasis by influencing the functions of insulin‐secreting cells in the pancreatic islets.
Lingling Chen, Yijun Lin, Xinyu Zhu, Shixuan Zhuo, Zixuan Li, Cheng Guo, Xiaoyi Ye, Jinzhu Chen, Shuying Wang, Yan Chen   +9 more
wiley   +1 more source

Synergistic Effects of Insulin-like Growth Factor-1 and Platelet-Derived Growth Factor-BB in Tendon Healing. [PDF]

Int J Mol Sci
Rieber J, Wolint P, Meier-Bürgisser G, Ongini E, Giovanoli P, Calcagni M, Snedeker JG, Buschmann J.   +7 more
europepmc   +1 more source

Effect of recombinant human insulin-like growth factor-1 on the inflammatory response to acute renal injury. [PDF]

, 1996
Nelson Goes, Joan Urmson, Dianne Heather Vincent, V Ramassar, Philip F. Halloran   +4 more
openalex   +1 more source