Results 171 to 180 of about 356,438 (307)

Acute neuroprotective synergy of erythropoietin and insulin-like growth factor I

open access: green, 2004
Murat Digicaylioglu   +4 more
openalex   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

open access: yesAdvanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou   +10 more
wiley   +1 more source

How insulin-like growth factor I binds to a hybrid insulin receptor type 1 insulin-like growth factor receptor. [PDF]

open access: yesStructure, 2022
Xu Y   +8 more
europepmc   +1 more source

Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle function.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1998
E. Barton-Davis   +4 more
semanticscholar   +1 more source

Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages

open access: yesAdvanced Science, EarlyView.
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu   +14 more
wiley   +1 more source

Upregulation of Insulin-like Growth Factor-I in Response to Chemotherapy in Children with Acute Lymphoblastic Leukemia. [PDF]

open access: yesInt J Mol Sci
Kocadag HB   +9 more
europepmc   +1 more source

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