Results 81 to 90 of about 470,139 (379)

Bioactive IGF-1 release from collagen-GAG scaffold to enhance cartilage repair in vitro. [PDF]

, 2015
Tissue engineering is a promising technique for cartilage repair. Toward this goal, a porous collagen-glycosaminoglycan (CG) scaffold was loaded with different concentrations of insulin-like growth factor-1 (IGF-1) and evaluated as a growth factor ...
Best, Serena M, Cameron, Ruth E, Ghose, Siddhartha, Mullen, Leanne M, Rushton, Neil, Wardale, John   +5 more
core   +2 more sources

Re-expression of IGF-II is important for beta cell regeneration in adult mice [PDF]

, 2012
Background The key factors which support re-expansion of beta cell numbers after injury are largely unknown. Insulin-like growth factor II (IGF-II) plays a critical role in supporting cell division and differentiation during ontogeny but its role in the
David Epstein, Franco Folli, Hassan Nakhai, James Young, Julia Herold, Luxian Zhou, Michael Khan, Stella Pelengaris, Sylvie Abouna, Tim Wilhelm Nattkemper   +9 more
core   +8 more sources

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Insulin-like growth factor II gene Apa I polymorphism is not associated with endometriosis susceptibility

Genetics and Molecular Biology, 2004
Insulin-like growth factor II (IGF2) has been shown to play a role in abnormal cell growth and carcinogenesis. We investigated if the IGF2 gene Apa I polymorphism at exon 9 was associated with the susceptibility to endometriosis, analyzing 120 women with
Yao-Yuan Hsieh, Chi-Chen Chang, Fuu-Jen Tsai, Ching-Tien Peng, Lian-Shun Yeh, Cheng-Chieh Lin   +5 more
doaj   +1 more source

Metabolic actions of insulin-like growth factor II in cultured adult rat hepatocytes are not mediated through the insulin-like growth factor II receptor [PDF]

Diabetologia, 1992
Short- and long-term regulation of hepatic carbohydrate metabolism by insulin-like growth factor II was studied in primary cultures of adult rat hepatocytes and compared to the metabolic potency of insulin. Insulin-like growth factor II stimulated glycogen synthesis from [14C]glucose, uptake of [3H]aminoisobutyric acid and [14C]lactate formation from ...
T. Braulke, Heinz Hartmann, A. Meyer-Alber   +2 more
openaire   +3 more sources

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Prostat adenokarsinomlarında IMP-3 ekspresyonunun araştırılması [PDF]

, 2012
Objective: Prostate cancer is the second most common cause of male cancer deaths after lung cancer in developed countries. The prognostic factors currently identified for prostate carcinoma include preoperative serum PSA, TNM staging system, histological
Tosun Yıldırım, Hülya, Şen Türk, Nilay   +1 more
core   +1 more source

Retroperitoneal Doege–Potter syndrome with intraoperative blood glucose monitoring

IJU Case Reports
Background Doege–Potter syndrome, characterized by solitary fibrous tumors and non‐islet cell tumor hypoglycemia, is rare. Here, we report a case of Doege–Potter syndrome in which retroperitoneal tumor resection was performed with continuous ...
Hirotaka Nagasaka, Takahisa Suzuki, Takuya Kondo, Mitsuyuki Koizumi, Hideyuki Terao, Yuko Murohashi, Yoichiro Okubo, Tomoyuki Yokose, Takeshi Kishida   +8 more
doaj   +1 more source

Effects of insulin, insulin-like growth factor-II, and nerve growth factor on neurite formation and survival in cultured sympathetic and sensory neurons

Journal of Neuroscience, 1986
Insulin and the insulin-like growth factors (IGFs) may directly affect the development of the nervous system. NGF, IGF-II, and insulin's effects on neurite formation and neuronal survival were studied in peripheral ganglion cell cultures from chick ...
E. Recio-Pinto, MM Rechler, D. Ishii
semanticscholar   +1 more source

β‐Galactosidase decreases the binding affinity of the insulin‐like‐growth‐factor‐II/mannose‐6‐phosphate receptor for insulin‐like‐growth‐factor II [PDF]

European Journal of Biochemistry, 1990
The insulin‐like growth‐factor‐II/mannose‐6‐phosphate (IGF‐II/Man6P) receptor binds two classes of ligands, insulin‐like growth factors and lysosomal enzymes. We have examined the ability of the lysosomal enzyme, β‐galactosidase, to modulate the binding of 125I‐IGF‐II to the receptor.
Wieland Kiess, Mark M. Sklar, Cheryl L. Thomas, S. Peter Nissley   +3 more
openaire   +3 more sources