Results 201 to 210 of about 90,101 (333)

Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines

Advanced Science, EarlyView.
This review offers a comprehensive overview of pharmaceutical nanotechnology strategies to address limitations associated with the complex material basis and relative mild therapeutic efficacy of Chinese herbal medicines, and summarizes the advantages of these strategies.
Jiameng Li, Ya‐Li Zhang, Tong Jin, Zhaokui Jin, Mengliang Zhu, Guangchao Qing, Jinchao Zhang, Zhisen Wang, Yan Mu, Jin Li, Qian Hua, Xing‐Jie Liang   +11 more
wiley   +1 more source

Activation of nestin‐positive duct stem (NPDS) cells in pancreas upon neogenic motivation and possible cytodifferentiation into insulin‐secreting cells from NPDS cells [PDF]

, 2004
So‐Yoon Kim, Seunghee Lee, Byeong‐Moo Kim, Eun Ho Kim, Bon‐Hong Min, M Bendayan, In‐Sun Park   +6 more
openalex   +1 more source

QSOX2‐Mediated Disulfide Bond Modification Enhances Tumor Stemness and Chemoresistance by Activating TSC2/mTOR/c‐Myc Feedback Loop in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
High QSOX2 enhances stemness, drug resistance, and metastasis of ESCC cells. QSOX2‐mediated disulfide bond modification activates mTOR/c‐Myc signaling. CAFs‐secreted IGF‐1 drives mTOR/c‐Myc/QSOX2 positive feedback loop. Combining Ebselen, rapamycin, and cisplatin induces tumor dormancy in mice.
Wo‐Ming Chen, Xiao‐Ping Zhang, Xiao Sun, Hai‐Cheng Liu, Yuan‐Yuan Yan, Xue Wei, Yu Liang, Yue Feng, Zhengjie Chen, Yongxu Jia, Chen Jiang, Qian Yan, Lei Li   +12 more
wiley   +1 more source

Insulin-Secreting Pituitary GH3 Cells: A Potential β-Cell Surrogate for Diabetes Cell Therapy

, 2000
Alberto M. Davalli, Francesca Galbiati, Federico Bertuzzi, Luca Polastri, Antonio E. Pontiroli, Lucia Perego, Massimo Freschi, G. Pozza, Franco Folli, Cesare Meoni   +9 more
openalex   +1 more source

Electrophysiological characterization of insulin secreting beta-cells in pancreatic tissue slices [PDF]

, 2004
Stephan Speier
openalex   +1 more source

Targeting IGF1R Overcomes Armored and Cold Tumor Microenvironment and Boosts Immune Checkpoint Blockade in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
IGF1R is highly expressed in the armored & cold tumors, and collagen mediates IGF1R at the transcriptional and post‐translational levels to promote TNBC cell invasion and immune escape and to stabilize its own structure by interacting with the collagen receptor DDR1.
Mengyun Wan, Jie Mei, Yun Cai, Ji Zhou, Ningyi Xue, Ying Jiang, Yan Zhang, Jingjing Huang, Yichao Zhu   +8 more
wiley   +1 more source

Novel actions of IGFBP-3 on intracellular signaling pathways of insulin-secreting cells [PDF]

, 2005
Xiaohong Chen, Robert J. Ferry
openalex   +1 more source

Glucose-dependent phosphorylation signaling pathways and crosstalk to mitochondrial respiration in insulin secreting cells. [PDF]

Cell Commun Signal, 2019
Santo-Domingo J, Galindo AN, Cominetti O, De Marchi U, Cutillas P, Dayon L, Wiederkehr A.   +6 more
europepmc   +1 more source

Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance

Advanced Science, EarlyView.
Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai, Kefei Wu, Qi Lin, Zhenzhen Cao, Yankun Jia, Ping Zhu   +5 more
wiley   +1 more source

A pituitary adenoma secreting high molecular weight adrenocorticotropin without evidence of Cushing's disease [PDF]

, 1987
Allolio, B., Kaulen, D., Reincke, Martin, Saeger, W., Winkelmann, W.   +4 more
core   +1 more source