The Application of the Insulin to C-Peptide Molar Ratio (ICPR) in Primary Screening for Insulin Antibodies in Type 2 Diabetes Mellitus Patients: A Further Quantitative Study on the Relationship Between ICPR and Insulin Antibodies [PDF]
Diabetes, Metabolic Syndrome and Obesity, 2023 Kai-Fang Hua,1,2 Bo-Yang Jing,3 Yan-Hui Wu1,4 1Department of Endocrinology, Xiang’an Hospital of Xiamen University, Xiamen, Fujian, People’s Republic of China; 2School of Medicine, Xiamen University, Xiamen, Fujian, People’s Republic of China; 3Hai Yuan ...
Hua KF, Jing BY, Wu YH
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Hyperinsulinemic hypoglycemia associated with insulin antibodies caused by exogenous insulin analog [PDF]
Endocrinology, Diabetes & Metabolism Case Reports, 2016 Insulin antibodies (IA) associated with exogenous insulin administration seldom caused hypoglycemia and had different characteristics from insulin autoantibodies (IAA) found in insulin autoimmune syndrome (IAS), which was first described by Dr Hirata in ...
Chih-Ting Su, Yi-Chun Lin
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Biosimilar insulin and insulin antibodies. [PDF]
J Diabetes Sci Technol, 2013 The introduction of biosimilar insulins in regulated markets is anticipated to happen in the next few years.1,2 However, biosimilar insulins are already on the market in a number of countries with little or no guidelines for approval of biosimilars and where approval is relatively easy to obtain.
Heinemann L, Owens D.
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Insulinoma presenting with anti-insulin antibodies [PDF]
Endocrinology, Diabetes & Metabolism Case ReportsAn 89-year-old woman presented with a 6-year history of occasional episodes of impaired consciousness that were relieved by ingestion of a snack. Three months before presenting to our hospital, she had been hospitalized in a local hospital with subdural ...
Rikako Nakajima +7 more
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A novel treatment of hyperinsulinemic hypoglycemia induced by insulin antibodies with alkali administration: a case report [PDF]
Journal of Medical Case Reports, 2019 Background Insulin autoimmune syndrome is a rare cause of hyperinsulinemic hypoglycemia characterized by autoantibodies to human insulin without previous insulin use.
Seiji Kobayashi +3 more
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Exogenous insulin antibody syndrome (EIAS): a clinical syndrome associated with insulin antibodies induced by exogenous insulin in diabetic patients [PDF]
Endocrine Connections, 2018 Insulin has been used for diabetes therapy and has achieved significant therapeutic effect. In recent years, the use of purified and recombinant human insulin preparations has markedly reduced, but not completely suppressed, the incidence of insulin ...
Xiaolei Hu, Fengling Chen
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A pitfall in diagnosing type B insulin resistance syndrome: Suspected antibody interference in a patient with insulin allergy [PDF]
Journal of Diabetes InvestigationThe patient was a 73‐year‐old man with diabetes who developed marked hyperglycemia after several years of insulin therapy. Investigations showed marked hyperinsulinemia, positive insulin antibodies with low affinity/high binding capacity, insulin ...
Satoru Manda +4 more
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Glutamic Acid Decarboxylase and Tyrosine Phosphatase-Related Islet Antigen-2 Positivity among Children and Adolescents with Diabetes in Korea [PDF]
Diabetes & Metabolism Journal, 2022 Autoantibodies against glutamic acid decarboxylase (GADA), tyrosine phosphatase-related islet antigen 2 (IA2A), insulin (INSA), and islet cells (ICA) are critical for determining the type of diabetes and management strategy in new-onset diabetes mellitus
Ka Young Kim +6 more
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Frontiers in Clinical Diabetes and Healthcare, 2023 ObjectiveThis study aimed to investigate the clinical implications of fasting serum insulin (FINS) levels in subjects with type 2 diabetes who were receiving insulin therapy.MethodsA total of 1,553 subjects with type 2 diabetes [774 subjects who had ...
Lingli Zhou +8 more
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Insulin Antibody-induced Diabetic Ketoacidosis in an Elderly Type 2 Diabetic Ameliorated with Prednisolone [PDF]
Journal of Clinical and Diagnostic Research, 2018 In the patients who are treated with insulin, the synthesis of insulin antibodies occasionally induce difficulty in glycaemic management. Insulin antibodies are now being closely examined in the context of diabetes treatment.
Yuko Matsumoto +4 more
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