Results 31 to 40 of about 269,490 (301)
Case Reports in Endocrinology, 2019 Background. Langerhans Cell Histiocytosis (LCH) is a rare inflammatory neoplasm characterized by an infiltration of organs by Langerin + (CD207+) and CD1a+ histiocytes.
Mathilde Sollier +15 more
doaj +1 more source
Diabetology & Metabolic Syndrome, 2021 Background The exact incidence, clinical features and uniform diagnostic criteria of exogenous insulin autoimmune syndrome (EIAS) are still unclear. The purpose of this study is to explore the clinical characteristics of EIAS and to provide a structural ...
Zuojun Li +5 more
doaj +1 more source
Frontiers in Endocrinology, 2023 ObjectiveTo examine the distribution and effects of the subclass of insulin antibodies on glucose control and side events in patients with type 2 diabetes treated with premixed insulin analog.MethodsA total of 516 patients treated with premixed insulin ...
Shuang Chen +6 more
doaj +1 more source
Gad65 is recognized by t-cells, but not by antibodies from nod-mice [PDF]
, 1994 Since the 64kDa-protein glutamic acid decarboxylase (GAD) is one of the major autoantigens in T-cell mediated Type 1 diabetes, its relevance as a T-cell antigen needs to be clarified. After isolation of splenic T-cells from non-obese diabetic (NOD) mice,
Seißler, Jochen +4 more
core +1 more source
Insulin-binding antibodies in relation to insulin therapy [PDF]
Journal of Clinical Pathology, 1963 Methods for detecting insulin binding or transporting antibodies are described, involving the use of radioactively labelled insulin (insulin 131 I). These antibodies are detected in a high proportion of patients receiving insulin, particularly those requiring large doses.
J N, HARRIS-JONES, H, MILLER, G, OWEN
openaire +2 more sources
Revisiting the IGF-1R as a breast cancer target
npj Precision Oncology, 2017 The type I insulin-like growth factor-1 receptor is a well-described target in breast cancer and multiple clinical trials examining insulin-like growth factor-1 receptor have been completed.
Roudy Chiminch Ekyalongo, Douglas Yee
doaj +1 more source
BMC Endocrine Disorders, 2021 Background MYL-1501D is a proposed biosimilar to insulin glargine. The noninferiority of MYL-1501D was demonstrated in patients with type 1 diabetes and type 2 diabetes in 2 phase 3 trials.
Bin Sun +11 more
doaj +1 more source
Metabolic and hormonal studies of Type 1 (insulin-dependent) diabetic patients after successful pancreas and kidney transplantation [PDF]
, 1991 Long-term normalization of glucose metabolism is necessary to prevent or ameliorate diabetic complications. Although pancreatic grafting is able to restore normal blood glucose and glycated haemoglobin, the degree of normalization of the deranged ...
Fiedler, F. +6 more
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Anti-Insulin Immune Responses Are Detectable in Dogs with Spontaneous Diabetes. [PDF]
PLoS ONE, 2016 Diabetes mellitus occurs spontaneously in dogs. Although canine diabetes shares many features with human type-1 diabetes, there are differences that have cast doubt on the immunologic origin of the canine disease.
Jong-Hyuk Kim +10 more
doaj +1 more source