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Insulin-induced lipohypertrophy: clinical and ultrasound characteristics
Сахарный диабет, 2018 Background: Lipohypertrophy is primary dermal complication of insulin therapy. The data on the prevalence of lipohypertrophy in diabetic subjects are inconsistent, that may be due to the lack of sensitivity and subjectivity of palpation as diagnostic ...
Vadim V. Klimontov +7 more
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No association between islet cell antibodies and coxsackie B, mumps, rubella and cytomegalovirus antibodies in non-diabetic individuals aged 7–19 years [PDF]
, 1991 Viral antibodies were tested in a cohort of 44 isletcell antibody-positive individuals age 7–19 years, and 44 of their islet cell antibody-negative age and sex-matched classmates selected from a population study of 4208 pupils who had been screened for ...
Muir, Peter +10 more
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Разработка и регистрация лекарственных средств, 2019 Introduction. IImmunogenicity identification of therapeutic proteins, such as human insulin analogues, is one of the most relevant and significant area in medicine and pharmaceuticals. Determination the possibility of producing neutralizing antibodies to
N. B. Abramenko +7 more
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Insulin autoantibodies as determined by competitive radiobinding assay are positively correlated with impaired beta-cell function — The Ulm-Frankfurt population study [PDF]
, 1991 Out of a random population of 4208 non-diabetic pupils without a family history of Type I diabetes 44 (1.05%) individuals had islet cell antibody (ICA) levels greater or equal to 5 Juvenile Diabetes Foundation (JDF) units. 39 of these ICA-positives could
N. Yassin I +14 more
core +1 more source
BMC Endocrine Disorders, 2019 Background Insulin injection, especially with insulin analogs, occasionally induces the production of insulin antibodies with high binding capacity and low affinity, similar to the insulin autoantibodies characteristic of insulin autoimmune syndrome (IAS)
Keizo Kaneko +9 more
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Rapid insulin-dependent endocytosis of the insulin receptor by caveolae in primary adipocytes. [PDF]
PLoS ONE, 2009 BACKGROUND:The insulin receptor is localized in caveolae and is dependent on caveolae or cholesterol for signaling in adipocytes. When stimulated with insulin, the receptor is internalized.
Siri Fagerholm +4 more
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Ankara Üniversitesi Tıp Fakültesi Mecmuası, 2021 Objectives:Chronic lymphocytic leukemia is the most common type of leukemia seen in adults worldwide. Hashimoto’s thyroiditis is the most common form of autoimmune thyroid disease.
Didar Yanardağ Açık
doaj +1 more source
Insulin autoimmune syndrome – a rare cause of hypoglycaemia: a report on 2 cases
Sri Lanka Journal of Diabetes Endocrinology and Metabolism, 2016 Insulin autoimmune syndrome (IAS, Hirata disease) is a rare cause of hypoglycaemia in countries other than Japan and Korea. It is a syndrome of hypoglycaemia with elevated insulin and insulin antibody levels.
M. S. A. Cooray +3 more
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Post-streptococcal antibodies are associated with metabolic syndrome in a population-based cohort. [PDF]
PLoS ONE, 2011 Streptococcal infections are known to trigger autoimmune disorders, affecting millions worldwide. Recently, we found an association between post-streptococcal autoantibodies against Protein Disulphide Isomerase (PDI), an enzyme involved in insulin ...
Adi Aran +6 more
doaj +1 more source
Frontiers in Physiology, 2018 Hashimoto's Thyroiditis (HT) is a common organ-specific autoimmune disorder associated with a high incidence, and insulin resistance is highly related to autoimmune.
Min Yang +5 more
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