Results 231 to 240 of about 805,287 (382)

Metabolic Syndrome and Insulin Resistance in Romania. [PDF]

Int J Mol Sci
Ştefan AG, Clenciu D, Mitrea A, Vladu IM, Protasiewicz-Timofticiuc DC, Roşu MM, Maria DT, Dinu IR, Gheonea TC, Vladu BE, Efrem IC, Moţa E, Moţa M.   +12 more
europepmc   +1 more source

Insulin resistance and hyperinsulinemia in individuals with small, dense low density lipoprotein particles. [PDF]

, 1993
Gerald M. Reaven, Y D Chen, Jørgen Jeppesen, Pierre Maheux, Ronald M. Krauss   +4 more
openalex   +1 more source

RAB3B Dictates mTORC1/S6 Signaling in Chordoma and Predicts Response to mTORC1‐Targeted Therapy

Advanced Science, EarlyView.
RAB3B is unveiled as a prominent oncogenic regulator in chordoma, which can block the DUSP12‐mediated dephosphorylation of p‐S6 (S235/236). The combination of RAB3B and p‐S6 indicates a good prognostic value and predicts mTORC1 inhibitors response for chordoma patients.
Jianxuan Gao, Jiali Jin, Runzhi Huang, Siqiao Wang, Sihui Song, Yu Zhang, Yongai Li, Jun Lin, Zhengyan Chang, Zongqiang Huang, Wei Sun, Huabin Yin, Dianwen Song, Jianru Xiao, Ping Wang, Tong Meng   +15 more
wiley   +1 more source

The positive correlation between amphiregulin and insulin resistance. [PDF]

Endocr Connect
Zhao Y, Lu T, Wu M, Hu X, Xiang R, Feng M, Lu H.   +6 more
europepmc   +1 more source

Roles of insulin resistance and beta-cell dysfunction in dexamethasone-induced diabetes. [PDF]

, 1992
Ai Ogawa, John H. Johnson, Makoto Ohneda, Chris T. McAllister, Lindsey Inman, Tausif Alam, R H Unger   +6 more
openalex   +1 more source

Targeted Delivery of α‐ketoglutarate to Macrophages in Bone: A Novel Therapeutic Strategy for Improving Fracture Healing in Type 2 Diabetes

Advanced Science, EarlyView.
The study reveals that glutaminolysis in macrophages is inhibited under type 2 diabetes mellitus (T2DM) conditions, which impedes fracture healing by reducing bone morphogenetic protein 2 (BMP2) production through increased cytosine methylation on the promoter.
Jing Wang, Jiahao Cao, Siqi Zhang, Hongli Chen, Xuebing Yu, Xinli Wang, Tianji Wang, Wei Cao, Wengang Dong, Xinsen Lin, Jia Li, Wei Lei, Yafei Feng   +12 more
wiley   +1 more source

Exploring the TyG Index and the Homeostasis Model Assessment of Insulin Resistance as Insulin Resistance Markers: Implications for Fibromyalgia Management and Understanding-A Narrative Review. [PDF]

Diagnostics (Basel)
Samavarchitehrani A, Mercantepe F, Behnoush AH, Klisic A.   +3 more
europepmc   +1 more source

Insulin Resistance in Humans

, 1982
Jerrold M. Olefsky
openalex   +1 more source

The insulin receptor: signalling mechanism and contribution to the pathogenesis of insulin resistance [PDF]

, 1991
H. U. H�ring
openalex   +1 more source

PLXDC1+ Tumor‐Associated Pancreatic Stellate Cells Promote Desmoplastic and Immunosuppressive Niche in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
This study uncovers the activation, heterogeneity, and regulatory roles of pancreatic stellate cells (PSCs) at single‐cell and spatial levels. It further identifies PLXDC1+ PSCs near aggressive LRRC15+ cancer‐associated myofibroblasts and SPP1+ macrophages, forming a desmoplastic and immunosuppressive tumor niche that promotes CD8+ T cell exhaustion ...
Yanhua Du, Yizhou Zhao, Judong Li, Jiaxin Wang, Shenglan You, Yao Zhang, Li Zhang, Jihong Yang, Hamid Alinejad‐Rokny, Shujie Cheng, Chenghao Shao, Duowu Zou, Youqiong Ye   +12 more
wiley   +1 more source