Results 241 to 250 of about 4,469,131 (358)

Risk of metabolic and vascular disease in South Asians: potential mechanisms for increased insulin resistance [PDF]

, 2008
Lesley Hall, Naveed Sattar, Jason M. R. Gill   +2 more
openalex   +1 more source

Type II Alveolar Epithelial Cells Promote Sepsis‐Induced Immunosuppression in Alveolar Macrophages via Exosomal lncRNA Rmrp Release

Advanced Science, EarlyView.
The S100A4/STAT3 axis promotes Rmrp transcription in AEC‐IIs and Rmrp expression in AEC‐II‐derived exosomes. Upon entry into AMs, Rmrp binds to and blocks the ubiquitination and degradation of ZFP36. Increased ZFP36 induced Pfkfb3 mRNA decay by binding to AREs in the 3′ UTR, curbing glycolysis and immune responses of AMs and aggravating SII and ...
Chengxi Liu, Weixia Xuan, Song Cao, Huayun Jia, Qian Wu, Xiaowu Tan, Qijie Wang, Xiaojun Li, Lisha Ding, Yaru Xiong, Meiyun Zhao, Longcheng Zheng, Yunzhu Xi, Jianhua Tan, Rong Li, Xulong Zhang, Wenjie Liu, Xu Wu   +17 more
wiley   +1 more source

Loss of Nucleobindin-2 Causes Insulin Resistance in Obesity without Impacting Satiety or Adiposity [PDF]

, 2018
Anthony Ravussin, Yun‐Hee Youm, Jil Sander, Seungjin Ryu, Kim Nguyen, Luis Varela, Gerald I. Shulman, Sviatoslav Sidorov, Tamas L. Horváth, Joachim L. Schultze, Vishwa Deep Dixit   +10 more
openalex   +1 more source

Identification of PKN2 and MOB4 as Coordinators of Collective Cell Migration

Advanced Science, EarlyView.
Through a genetic screen, PKN2 and MOB4 are identified as two proteins regulating the healing of an epithelial model wound. PKN2 promotes collective cell migration by maintaining the cohesion of cell monolayers from their lateral junctions, whereas MOB4 restrains collective cell migration and provides a lamellipodial cue for front‐rear polarity in ...
Artem I. Fokin, Yueying Lin, Dmitry Y. Guschin, Hsiang‐Ying Chen, John James, Jie Yan, Pascal Silberzan, Alexis M. Gautreau   +7 more
wiley   +1 more source

Prediction Model for Insulin Resistance and Implications for MASLD in Youth: A Novel Marker, the Pediatric Insulin Resistance Assessment Score. [PDF]

Yonsei Med J
Song K, Lee E, Youn YH, Baik SJ, Shin HJ, Lee JW, Chae HW, Lee HS, Kwon YJ.   +8 more
europepmc   +1 more source

Relation of resistin levels with cardiovascular risk factors, insulin resistance and inflammation in naïve diabetes obese patients [PDF]

, 2010
Daniel Antonio de Luis, M. González Sagrado, R. Conde, R. Aller, Olatz Izaola, Beatriz de la Fuente, José Luis Pérez Castrillón, E. Romero   +7 more
openalex   +1 more source

Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance.

Journal of Clinical Investigation, 1995
G. Hotamisligil, P. Arner, J. Caro, R. Atkinson, B. Spiegelman   +4 more
semanticscholar   +1 more source

A Patient‐Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery

Advanced Science, EarlyView.
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang, Chaohu Wang, Jun Fan, Zexin Chen, Haoying Yu, Yawen Bai, Tingcheng Zhang, Qianchao Zhu, Yiwen Feng, Peirong Niu, Jiaqian Chen, Liping Yang, Xueying Li, Lei Yu, Songtao Qi, Yi Liu   +15 more
wiley   +1 more source

Associations between asprosin, insulin resistance, and oxidative stress in adults with obesity. [PDF]

Sci Rep
Kościuszko M, Buczyńska A, Duraj E, Adamska A, Siewko K, Krętowski AJ, Popławska-Kita A.   +6 more
europepmc   +1 more source

Calcium signalling and ER stress in insulin resistance and atherosclerosis

, 2016
Lale Özcan, Ira Tabas
openalex   +2 more sources