Results 241 to 250 of about 805,287 (382)

Predictive role of insulin resistance surrogates in gallstone disease. [PDF]

Medicine (Baltimore)
Liu J, Hu Z, Bo D, Zhang X, Zhang Z, Liu X.   +5 more
europepmc   +1 more source

Insulin resistance in liver cirrhosis. Positron-emission tomography scan analysis of skeletal muscle glucose metabolism. [PDF]

, 1993
O. Selberg, Wolfgang Burchert, Jan Hoff, G.‐J. Meyer, H. Hundeshagen, E. Radoch, H. J. Balks, Manfred J. Müller   +7 more
openalex   +1 more source

Asprosin‐FABP5 Interaction Modulates Mitochondrial Fatty Acid Oxidation through PPARα Contributing to MASLD Development

Advanced Science, EarlyView.
Aided by FABP5, abnormally elevated asprosin in hepatocytes enters the nucleus, targets and inhibits PPARα binding to the CPT1A promoter, thereby suppressing FAO. Circulating asprosin exacerbates insulin resistance, collectively driving MASLD progression.
Yuan‐Yuan Yu, Min Feng, Yi Chen, Hong‐Lin Jia, Qi Zhang, Ming Tong, Yan‐Xi Li, Yu Zhao, Xin‐Xin Liu, Shi‐Feng Cao, Zheng‐kai Wang, Hou‐wei Li, Xue Liu, Yan Zhang   +13 more
wiley   +1 more source

How much insulin resistance in polycystic ovary syndrome? Comparison of HOMA-IR and insulin resistance (Belfiore) index models

Archives of Medical Science, 2019
Krzysztof C. Lewandowski, Elżbieta Skowrońska-Jóźwiak, Katarzyna Łukasiak, Katarzyna Gałuszko, Aleksandra Dukowicz, Magdalena Cedro, Andrzej Lewiński   +6 more
doaj   +1 more source

Advances in Insulin Resistance-Molecular Mechanisms, Therapeutic Targets, and Future Directions. [PDF]

Int J Mol Sci
Ahn B.
europepmc   +1 more source

Familial Type C Syndrome of Insulin Resistance and Short Stature with Possible Autosomal Dominant Transmission.

, 1989
Fumiko Nakamura, Masato Taira, Naotake Hashimoto, Hideichi Makino, Nozomu Sasaki   +4 more
openalex   +2 more sources

LIMA1 O‐GlcNAcylation Promotes Hepatic Lipid Deposition through Inducing β‐catenin‐Regulated FASn Expression in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
Early diagnosis and treatment of metabolic dysfunction‐associated steatotic liver disease (MASLD) remains a significant challenge. This study indicates that serum sEV LIMA1 may serve as a noninvasive biomarker for MASH. The HCF1/OGT complex induces O‐GlcNAcylation of the LIMA1 protein, and subsequently promotes lipid accumulation in hepatocytes by ...
Fuji Yang, Yifei Chen, Guojun Zheng, Kefeng Gu, Lin Fan, Tingfen Li, Ling Zhu, Yongmin Yan   +7 more
wiley   +1 more source

Single nucleotide polymorphisms in the CDH18 gene affect growth traits in Hu sheep

Animal Research and One Health, EarlyView., 2023
Abstract Growth traits are critical economic traits in sheep. Genetic polymorphism has a great influence on the improvement of sheep traits. The aim of this study was to analyze the effect of cadherin 18 (CDH18) gene polymorphisms on growth traits in Hu sheep.
Tianyi Liu, Yazhen Bi, Jingjing Bao, Mingyu Shang, Wenping Hu, Li Zhang   +5 more
wiley   +1 more source

Reappraising the relationship between hyperinsulinemia and insulin resistance in PCOS. [PDF]

J Endocrinol
Houston EJ, Templeman NM.
europepmc   +1 more source

Insulin resistance in Type 2 (non-insulin-dependent) diabetic patients and their relatives is not associated with a defect in the expression of the insulin-responsive glucose transporter (GLUT-4) gene in human skeletal muscle [PDF]

, 1992
Johan G. Eriksson, László Korányi, R. E. Bourey, C. Schalin-J�ntti, E. Wid�n, Mike Mueckler, Alan Permutt, Leif Groop   +7 more
openalex   +1 more source