Results 241 to 250 of about 4,110,467 (359)

Insulin Resistance/Hyperinsulinemia Should Be Considered in the Prevention and Treatment of Essential Hypertension. [PDF]

Biomedicines
Fazio S, Affuso F.
europepmc   +1 more source

The pathogenesis of insulin resistance: integrating signaling pathways and substrate flux.

Journal of Clinical Investigation, 2016
V. Samuel, G. Shulman
semanticscholar   +1 more source

Label‐Free Leukocyte Biophysical Profiling Using Impedance‐Deformability Cytometry for Rapid Cardiovascular Risk Stratification

Advanced Science, EarlyView.
This study presents an impedance‐based single‐cell profiling platform that quantifies the electrical and mechanical properties of neutrophils across in vitro, in vivo, and clinical samples. The approach reveals distinct biophysical alterations associated with type 2 diabetes (T2DM) and cardiovascular complications, suggesting its potential utility for ...
Linwei He, Hui Min Tay, Feng Chen, Hong Sheng Cheng, Liang De Wang, Qiqi Nam, Arunachalam Thannirmalai, Lingyan Gong, Aram J. Chung, Nguan Soon Tan, King Ho Holden Li, Rinkoo Dalan, Siu Ling Wong, Han Wei Hou   +13 more
wiley   +1 more source

Interactive and Joint Effects of Obesity and Insulin Resistance on Hypertension in Adolescents and the Mediating Role of Insulin Resistance-Five Provinces, China. [PDF]

Nutrients
Zhu H, Zhang Z, Feng Y, Wu Q, Zhang R, Liu T, Liu D, Chen X, Dong X.   +8 more
europepmc   +1 more source

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

Advanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying, Hangping Fan, Yunhe Wang, Ruhong Jiang, Dongsheng Cai, Hui Cheng, Hao Wang, Chenyang Jiang, Ping Liang   +8 more
wiley   +1 more source

Metabolic crossroads in insulin resistance: exploring lipid dysregulation and inflammation. [PDF]

Front Immunol
Saadati S, Godini R, Reddy A, Teede H, Mousa A.   +4 more
europepmc   +1 more source

LIGHT-ROASTED GREEN COFFEE EXTRACT IMPROVED ADIPONECTIN, INSULIN RESISTANCE, AND METABOLIC PROFILE OF METABOLIC SYNDROME RAT MODEL

, 2017
Mifetika Lukitasari, Dwi Adi Nugroho, Mohammad Saifur Rohman, Nur Ida Panca Nugrahini, Teguh Wahyu Sardjono   +4 more
openalex   +2 more sources

Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome.

Journal of Clinical Investigation, 2006
T. Kadowaki, T. Yamauchi, N. Kubota, K. Hara, K. Ueki, K. Tobe   +5 more
semanticscholar   +1 more source

GALNT10 Affects O‐Glycosylation of IGFBP7 to Promote Tumor Vascular Remodeling and Metastasis of Ovarian Cancer

Advanced Science, EarlyView.
The glycosyltransferase GALNT10 facilitates ovarian cancer metastasis through the induction of tumor cell EMT and tumor vascular dysfunction. GALNT10 enhanced the extracellular secretion of IGFBP7 through O‐GalNAc glycosylation modification at the T188 site, which subsequently interacts with CD93 on endothelial cells, leading to vascular remodeling ...
Yanan Zhang, Ayala Zuha, Zhangxin Wu, Aiping Luo, Bixia Jin, Qinkun Sun, Yuan Li, Qiyu Liu, Hongyan Guo, Chunliang Shang   +9 more
wiley   +1 more source