Results 271 to 280 of about 4,252,621 (405)

Predictive role of insulin resistance surrogates in gallstone disease. [PDF]

Medicine (Baltimore)
Liu J, Hu Z, Bo D, Zhang X, Zhang Z, Liu X.   +5 more
europepmc   +1 more source

Magnesium deficiency produces insulin resistance and increased thromboxane synthesis.

, 1993
Jerry L. Nadler, TA Buchanan, Rama Natarajan, I. Antonipillai, Richard N. Bergman, Robert K. Rude   +5 more
openalex   +1 more source

Lipid Droplet‐Organized MDM2‐Mediated P53 Degradation: A Metabolic Switch Governing Diet‐Driven Tumor Progression

Advanced Science, EarlyView.
Tumor‐associated TP53 inactivation correlates with lipid droplet (LD) accumulation. High‐fat diets drive Cyb5r3‐Myh9‐mediated p53 enrichment on LD surfaces, accelerating its degradation while upregulating LD‐promoting factor CD36 expression to establish a feed‐forward loop. LD suppression or dietary intervention restores p53 and inhibits tumorigenesis,
Haiyang Liu, Lin Jing, Yixin Li, Jinxing Zhou, Xiaohui Cui, Sen Li, Shijie Yang, Fangming Kan, Junfeng Du, Wentao Zhong, Sheng Yu, Ning Wang, Xing Jia, Junhui Li, Pan Nie, Zhenzhong Chen, Ying Han, Lingxi Jiang, Xiyun Yan, Hongxia Duan, Baiyong Shen   +20 more
wiley   +1 more source

Reappraising the relationship between hyperinsulinemia and insulin resistance in PCOS. [PDF]

J Endocrinol
Houston EJ, Templeman NM.
europepmc   +1 more source

Growth hormone, insulin-like growth factor-1 and insulin resistance in cirrhosis [PDF]

, 1994
E Shmueli
openalex   +1 more source

Unraveling Tissue‐Specific Fatty Acid Biosynthesis and Inter‐Tissue Crosstalk in Mice through Stable‐Isotope Tracing Metabolomics

Advanced Science, EarlyView.
Biosynthesis rates of 13 FFAs are quantitatively calculated in 15 tissues from glucose and an analytical framework to quantitatively calculate inter‐tissue communications of fatty acids between the liver and other tissues is developed. Moreover, the approach is extended to aging condition and a system‐wide decline of fatty acid synthesis in peripheral ...
Beizi Xing, Ruohong Wang, Tianzhang Kou, Wenbin Liu, Zheng‐Jiang Zhu   +4 more
wiley   +1 more source

Advances in Insulin Resistance-Molecular Mechanisms, Therapeutic Targets, and Future Directions. [PDF]

Int J Mol Sci
Ahn B.
europepmc   +1 more source

Hexokinase‐2 as a Therapeutic Target: Alleviating Herpes Simplex Keratitis Through Metabolic Reprogramming

Advanced Science, EarlyView.
Herpes Simplex Virus Type 1 (HSV‐1) infection triggers metabolic reprogramming in corneal cells, shifting from mitochondrial respiration to aerobic glycolysis with marked upregulation of Hexokinase‐2 (HK2). This study identifies HK2 as a therapeutic target: inhibiting HK2 with lonidamine significantly reduces viral replication and promotes corneal ...
Dan Jiang, Yining Sun, Xintong Yu, Ruoqi Wang, Yuting Zhang, Jinjie Yu, Shuang Xie, Yujia Cai, Yuhong Luo, Wei Chen   +9 more
wiley   +1 more source

The Metabolic Cardiovascular Syndrome: Syndrome X, Reavenʼs Syndrome, Insulin Resistance Syndrome, Atherothrombogenic Syndrome

, 1992
Ingvar Hjermann
openalex   +1 more source

Insulin resistance causes inflammation in adipose tissue

Journal of Clinical Investigation, 2018
Mitsugu Shimobayashi, Verena Albert, B. Woelnerhanssen, Irina C. Frei, Diana Weissenberger, A. C. Meyer-Gerspach, Nicolas Clement, S. Moes, M. Colombi, J. A. Meier, Marta M. Swierczynska, P. Jenö, C. Beglinger, R. Peterli, M. Hall   +14 more
semanticscholar   +1 more source