Results 281 to 290 of about 3,853,066 (390)

Multicargo Porous Cochlear Electrode Coating for Antifibrosis After Cochlear Implantation

Advanced Science, EarlyView.
This study presents a novel porous drug‐loading coating for cochlear electrodes, utilizing MA‐PDMS infused with GelMA hydrogel containing dexamethasone and MXene nanoparticles. The coating enhances biocompatibility, enables sustained drug release, reduces fibrosis, and preserves residual hearing post‐CI.
Lei Ren, Yangnan Hu, Xiaoqiong Ding, Menghui Liao, Tian Shen, Sixing Cao, Hui Zhang, Hong Cheng, Yanru Qi, Pan Feng, Xinyi Pang, Ling Lu, Huan Wang, Wenwen Liu, Renjie Chai, Lin Cheng   +15 more
wiley   +1 more source

Exploring the mechanisms of Chaige Kangyi Recipe in treating recurrent pregnancy loss with insulin resistance. [PDF]

Sci Rep
Wu J, Pan Y, Lu Y, Qian J, Zhang J, Xue Y, Xiao C, Qiu Y, Xie M, Li S.   +9 more
europepmc   +1 more source

A Bead‐Based Quantum Dot Immunoassay Integrated with Multi‐Module Microfluidics Enables Real‐Time Multiplexed Detection of Blood Insulin and Glucagon

Advanced Science, EarlyView.
The quantum dot integrated real‐time ELISA or QIRT‐ELISA system integrates a bead‐based quantum dot‐mediated immunoassay (BQI) with a modular microfluidic system to continuously monitor insulin and glucagon in whole blood samples and in a multiplexed setting.
Hesam Abouali, Sanjana Srikant, Md Fahim Al Fattah, Nicole G. Barra, Darryl Chan, Dayan Ban, Jonathan D. Schertzer, Mahla Poudineh   +7 more
wiley   +1 more source

Understanding Diabetic Cardiomyopathy: Insulin Resistance and Beyond. [PDF]

Heart Int
Binu AJ, Kapoor N.
europepmc   +1 more source

High Fat Low Carbohydrate Diet Is Linked to CNS Autoimmunity Protection

Advanced Science, EarlyView.
Mapping global epidemiological data to macronutrient supply reveals high carbohydrate, in contrast to high fat supply, associates with increased multiple sclerosis (MS) prevalence and incidence. This is confirmed in a mouse MS model, experimental autoimmune encephalomyelitis (EAE), using isocaloric diets: a high carbohydrate diet aggravates, a high ...
Duan Ni, Jian Tan, Julen Reyes, Alistair M Senior, Caitlin Andrews, Jemma Taitz, Camille Potier‐Villette, Claire Wishart, Alanna Spiteri, Laura Piccio, Nicholas Jonathan Cole King, Romain Barrès, David Raubenheimer, Stephen James Simpson, Ralph Nanan, Laurence Macia   +15 more
wiley   +1 more source

Reply to: "Dynamic imaging of macrophages in MASLD: A major interest in insulin resistance and outside the liver". [PDF]

JHEP Rep
Liu Y, Schilling JD.
europepmc   +1 more source

Unraveling the Microenvironment and the Pathogenic Axis of HIF‐1α–Visfatin–Fibrosis in Autoimmune Pancreatitis Using a Single‐Cell Atlas

Advanced Science, Volume 12, Issue 12, March 27, 2025.
Single‐cell RNA sequencing reveals that type 1 AIP exhibits increased amount and subtypes of B and plasma cells, particularly IgG4+ plasma cells, along with an expansion of Tfh and T helper CD4+ cells. Both AIP types share upregulation of HIF1A+ classical monocytes, which promote pancreatic fibrosis through increased visfatin production.
Deyu Zhang, Congjia Ma, Zhen Wang, Yanfang Liu, Zaoqu Liu, Wanshun Li, Yue Liu, Chang Wu, Liqi Sun, Fei Jiang, Hui Jiang, Xiaoju Su, Lisi Peng, Jiayu Li, Xinyue Wang, Hua Yin, Dongling Wan, Yuyan Zhou, Xiaorong Tian, Shiyu Li, Zhendong Jin, Baoan Ji, Zhaoshen Li, Haojie Huang   +23 more
wiley   +1 more source

CORRELATION BETWEEN TRAUMATIC BRAIN INJURY, OBESITY AND INSULIN-RESISTANCE - A CASE REPORT. [PDF]

J Rehabil Med Clin Commun
Wilde L, Ruysscher C, Oostra K.
europepmc   +1 more source

Berberine is a Novel Mitochondrial Calcium Uniporter Inhibitor that Disrupts MCU‐EMRE Assembly

Advanced Science, Volume 12, Issue 17, May 8, 2025.
Berberine, a safe and FDA‐approved drug, is identified as a novel mitochondrial calcium uniporter (MCU) inhibitor. By disrupting MCU‐EMRE interaction, Berberine prevents mitochondrial calcium overload and protects against ischemia/reperfusion injury, offering a promising therapeutic strategy for diseases linked to mitochondrial calcium dysregulation ...
Haixin Zhao, Siqi Chen, Nian Cao, Wenjun Wu, Guangqin Liu, Jun Gao, Jiayi Chen, Ting Li, Dingyi Lu, Lingmin Zeng, Haizhen Zhu, Weina Zhang, Qing Xia, Teng Li, Tao Zhou, Xue‐Min Zhang, Ai‐Ling Li, Xin Pan   +17 more
wiley   +1 more source

Experimental cell models of insulin resistance: overview and appraisal. [PDF]

Front Endocrinol (Lausanne)
Yang Y, Wang TT, Xie HA, Hu PP, Li P.
europepmc   +1 more source