Top-Down and Intact Protein Mass Spectrometry Data Visualization for Proteoform Analysis Using VisioProt-MS [PDF]
Bioinformatics and Biology Insights, 2019 The rise of intact protein analysis by mass spectrometry (MS) was accompanied by an increasing need for flexible tools allowing data visualization and analysis.
Jean Lesne +3 more
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Characterizing Intact IgA2 Antibody and Its Size Variants Using Native Mass Spectrometry and a Tandem MS-based Charge Reduction Approach [PDF]
Zhipu Xuebao, 2022 Characterization of protein structures at multiple levels plays an essential role in study on protein functions. Structural analysis at the intact protein or intact complex level allows access of information on aspects including level of post ...
CHEN Qing-rong;CHAIHU Ling-xiao;CHEN Tao;WANG Guan-bo
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Applications of Tandem Mass Spectrometry (MS/MS) in Protein Analysis for Biomedical Research
Molecules, 2022 Mass Spectrometry (MS) allows the analysis of proteins and peptides through a variety of methods, such as Electrospray Ionization-Mass Spectrometry (ESI-MS) or Matrix-Assisted Laser Desorption Ionization-Mass Spectrometry (MALDI-MS).
Anca-Narcisa Neagu +5 more
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Microfluidic devices for protein analysis using intact and top‐down mass spectrometry
View, 2023 Top‐down mass spectrometry (TD‐MS) provides unique information on compositions, structures, and functions of proteins or protein complexes and has been recognized as a powerful approach to complement conventional tools in protein analysis.
Xinyang Shao, Yanyi Huang, Guanbo Wang
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Single-molecule protein identification by sub-nanopore sensors. [PDF]
PLoS Computational Biology, 2017 Recent advances in top-down mass spectrometry enabled identification of intact proteins, but this technology still faces challenges. For example, top-down mass spectrometry suffers from a lack of sensitivity since the ion counts for a single ...
Mikhail Kolmogorov +4 more
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Rapid MRSA detection via tandem mass spectrometry of the intact 80 kDa PBP2a resistance protein
Scientific Reports, 2021 Treatment of antibiotic-resistant infections is dependent on the detection of specific bacterial genes or proteins in clinical assays. Identification of methicillin-resistant Staphylococcus aureus (MRSA) is often accomplished through the detection of ...
Jason R. Neil +11 more
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Journal of Extracellular Vesicles, 2022 Extracellular vesicles (EVs) are blood‐borne messengers that coordinate signalling between different tissues and organs in the body. The specificity of such crosstalk is determined by preferential EV docking to target sites, as mediated through protein ...
Julia Bauzá‐Martinez +3 more
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In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM
Nature Communications, 2022 Hsu and co-workers integrate cryo-electron tomography, cryo-electron microscopy and mass spectrometry to reveal the structural polymorphism of a pig coronavirus spike protein within intact viral particles, and how glycosylation modulates the ...
Cheng-Yu Huang +14 more
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Analysis of Bovine Kappa-Casein Glycomacropeptide by Liquid Chromatography–Tandem Mass Spectrometry
Foods, 2021 Caseinomacropeptide (CMP) is released from bovine kappa-casein after rennet treatment and is one of the major peptides in whey protein isolate. CMP has in vitro anti-inflammatory and antibacterial activities.
Yunyao Qu +3 more
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Molecules, 2020 The effectiveness of a synthesized matrix, α-cyano-5-phenyl-2,4-pentadienic acid (CPPA), for protein analysis by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) in complex samples such as foodstuff and ...
Antonio Monopoli +3 more
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