Results 101 to 110 of about 9,111 (181)

Exploring the impact of baseline and on‐treatment variables on durability of responses to fostemsavir through weeks 96 and 192 in the phase 3 BRIGHTE study

HIV Medicine, Volume 27, Issue 3, Page 386-396, March 2026.
Abstract Objectives The gp120‐directed attachment inhibitor fostemsavir was effective in people with multidrug‐resistant (MDR) HIV‐1 in the BRIGHTE study. Understanding factors associated with virologic response can help clinicians optimize treatment and identify individuals for fostemsavir‐based regimens.
M. Gartland, X. Wang, Q. Liao, B. Li, F. Du, M. Krystal, A. R. Tenorio, A. Pierce, J. R. Castillo‐Mancilla   +8 more
wiley   +1 more source

HIV Dynamics and Integrase Inhibitors

Antiviral Chemistry and Chemotherapy, 2009
The integrase inhibitor (INI) raltegravir has shown promising results in clinical trials to date, reducing second phase HIV RNA levels by 70% in comparison with standard regimens. These trial results have been limited by the 50 copies/ml detection limit of the HIV RNA assay and have not investigated the effect of an INI regimen on levels of latently ...
openaire   +2 more sources

Late diagnosis of paediatric HIV infection in high‐income countries: Lessons from the HIV Perinatal Virtual Clinic

HIV Medicine, Volume 27, Issue 3, Page 477-484, March 2026.
Abstract Introduction Timely diagnosis of HIV in children remains a challenge in all settings including low‐prevalence, high‐income countries (HIC). We aimed to characterize the prevalence of late diagnosis, and prior missed diagnostic opportunities among new presentations of paediatric HIV in HIC referred to an international Perinatal Virtual Clinic ...
Carolina Curto, M. Tritzali, A. Bamford, A. C. Bailey, E. G. H. Lyall, N. E. Mackie, N. Tickner, C. Foster, on behalf of the PVC   +8 more
wiley   +1 more source

Antimicrobial Resistance in Salmonella Across Aquaculture, Seafood and Related Aquatic Environments: A Scoping Review With Exploratory Textual Analysis

Reviews in Aquaculture, Volume 18, Issue 2, March 2026.
This scoping review with textual analysis maps antimicrobial resistance in Salmonella across aquaculture, seafood, and related aquatic environments. Across 93 studies, recurrent MDR patterns suggest sentinel serotypes (S. Typhimurium, S. Newport) and a minimal antimicrobial susceptibility testing (AST) panel to guide matrix‐stratified One Health ...
Cristiane Coimbra de Paula, Yuri Duarte Porto, Vinícius Silva Castro, Érica do Carmo Dias Matos, Adelino Cunha‐Neto, Ricardo César Tavares Carvalho, Luciana Kimie Savay‐da‐Silva, Eduardo Eustáquio de Souza Figueiredo, Tathiana Ferguson Motheo   +8 more
wiley   +1 more source

HIV integrase [PDF]

Science-Business eXchange, 2008
openaire   +3 more sources

Integrase-On-Demand: bioprospecting integrases for targeted genomic insertion of genetic cargo. [PDF]

Nucleic Acids Res
McClain HM, Lowrey LC, Quinto LB, Torrance EL, Gagliano TR, Isaacs FJ, Schoeniger JS, Williams KP, Mageeney CM.   +8 more
europepmc   +1 more source

Identification of cognate recombination directionality factors for large serine recombinases by virtual pulldown. [PDF]

Nucleic Acids Res
Shin H, Holland A, Alsaleh A, Retiz AD, Pigli YZ, Taiwo-Aiyerin OT, Peña Reyes T, Bello AJ, Quan J, Tang W, Olorunniji FJ, Rice PA.   +11 more
europepmc   +2 more sources

Gene-sized editing for the therapy of genetic diseases. [PDF]

Funct Integr Genomics
Padureanu T, Cocoș R, Matache IM, Bucur O.   +3 more
europepmc   +1 more source

Antimicrobial Resistant Factors in <i>Klebsiella pneumoniae</i> Strains Isolated From Urinary Tract Infections, Wound Infections, Hospital Wastewater, and Cervical Cancers From Ghana, Togo, and Benin. [PDF]

Int J Genomics
Yakubu B.
europepmc   +1 more source

The TIGER/Islander resource for genomic islands. [PDF]

Microbiol Resour Announc
Yu SL, McClain HM, Torrance EL, Schoeniger JS, Mageeney CM, Williams KP.   +5 more
europepmc   +1 more source