Results 101 to 110 of about 31,694 (314)
INTEGRALL: a database and search engine for integrons, integrases and gene cassettes
Bioinform., 2009 INTEGRALL is a freely available, text-based search system developed with the aim of collecting and organizing information on integrons in a single database.
A. Moura +5 more
semanticscholar +1 more source
Draft Genome Sequence of Mycobacterium elephantis Strain Lipa. [PDF]
, 2015 We report the draft genome sequence of Mycobacterium elephantis strain Lipa from a sputum sample of a patient with pulmonary disease. This is the first draft genome sequence of M.
Chiu, Charles Y +5 more
core +1 more source
HIV-1 Integrase Inhibitors That Are Active against Drug-Resistant Integrase Mutants
Antimicrobial Agents and Chemotherapy, 2020 The currently recommended first-line therapy for HIV-1-infected patients is an integrase (IN) strand transfer inhibitor (INSTI), either dolutegravir (DTG) or bictegravir (BIC), in combination with two nucleoside reverse transcriptase inhibitors (NRTIs). Both DTG and BIC potently inhibit most INSTI-resistant IN mutants selected by the INSTIs raltegravir
Stephen H. Hughes +6 more
openaire +3 more sources
Near‐Infrared Fluorescent Single‐Walled Carbon Nanotubes for Biosensing
Small, EarlyView.Near‐infrared fluorescent single‐walled carbon nanotubes (SWCNTs) stand out as versatile biosensors due to their spectral overlap with the biological transparency window, surface‐sensitive fluorescence emission, and chemical modularity. This review offers a concise guide to understanding the photophysics of SWCNTs, various functionalization strategies,
Srestha Basu, Gili Bisker
wiley +1 more source
A mathematical model of bacteria capable of complete oxidation of ammonium predicts improved nitrogen removal and reduced production of nitrous oxide [PDF]
, 2017 The removal of excess nutrients from water ecosystems requires oxidation of toxic ammonium by two types of bacteria; one oxidizes ammonium to nitrite and the other oxidizes nitrite to nitrate.
Ebenhöh, Oliver, Pokhilko, Alexandra
core
CRISPR/Cas9‐edited tumor‐associated immune cells in cancer immunotherapy
VIEW, EarlyView.Abstract Immuno‐oncology represents an emerging field that has significantly transformed tumor therapeutics, with immune cells serving as the cellular foundations of cancer immunotherapy. Due to its high efficiency and sensitivity, CRISPR/Cas9 genome editing is a highly promising technique for precise and rapid gene modification.
Yuhui Ma +6 more
wiley +1 more source
TOX4 and NOVA1 proteins are partners of the LEDGF PWWP domain and affect HIV-1 replication.
PLoS ONE, 2013 PWWP domains are involved in the chromatin attachment of several proteins. They bind to both DNA and proteins and their interaction with specific histone methylation marks define them as a new class of histone code readers.
Mehdi Morchikh +6 more
doaj +1 more source
Classification of Tangle Solutions for Integrases, A Protein Family that Changes DNA Topology [PDF]
arXiv, 2005 Integrase proteins acting on circular double-stranded DNA often change its topology by transforming unknotted circles into torus knots and links. Two systems of tangle equations--corresponding to the two initial DNA sequences--arise when modelling this transformation: direct and inverted.
arxiv
Repressing Integrase attachment site operation with CRISPR-Cas9 in E. coli [PDF]
, 2017 Serine integrases are bacteriophage proteins responsible for integrating the phage genome into that of the host. Synthetic biologists have co-opted these proteins into useful tools for permanent DNA logic, utilizing their specific DNA recombination ...
Murray, Richard M., Shur, Andrey
core +1 more source
Andrology, EarlyView.Abstract Background Erectile dysfunction in people living with HIV is a multifactorial disease, but the role of penile vascular status assessed by dynamic penile color Doppler echography is underexplored. Objectives This study assessed penile vascular status in young males living with HIV experiencing erectile dysfunction, comparing them to HIV ...
Giorgio Tiecco +9 more
wiley +1 more source