Results 141 to 150 of about 81,327 (201)

Comparative clinical and prognostic significance of integrin αvβ3, αvβ5, and αvβ6 in osteosarcoma. [PDF]

Front Oncol
You C, Zeng F, Zhang S, Xu J, Ren T, Xie L, Song Y, Tang X, Wei R.   +8 more
europepmc   +1 more source

Molecular basis for the recognition of 24-(S)-hydroxycholesterol by integrin αvβ3. [PDF]

Sci Rep, 2023
Gc JB, Chen J, Pokharel SM, Mohanty I, Mariasoosai C, Obi P, Panipinto P, Bandyopadhyay S, Bose S, Natesan S.   +9 more
europepmc   +1 more source

Mitochondria‐targeted nanomedicine for cancer therapy: Targeting strategies, therapeutic mechanisms, and translational challenges

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
This review highlights recent advances in mitochondria‐targeted nanomedicine for cancer therapy. It summarizes key targeting strategies and delineates four principal therapeutic mechanisms: oxidative stress–induced mitochondrial dysfunction, disruption of energy metabolism, direct mitochondrial damage, and induction of immunogenic cell death.
Linfeng Xiao, Xiaowei Chang, Jun Zhang, Yinshan Hong, Wenhui Cao, Zhewu Zhao, Yu‐E. Wang, Yanling Yang   +7 more
wiley   +1 more source

Secondary Site Ligand for Integrin αVβ3 Enables Targeted mRNA Delivery. [PDF]

Angew Chem Int Ed Engl
Bayer S, García-García M, Senatore R, Stratoudaki M, Markhof A, Berger-Becvar A, Parianou AS, Rademacher C.   +7 more
europepmc   +1 more source

S100A8 Mediating TLR4/NF‐κB Axis Activation to Inhibit Diabetic Foot Healing in Bacterial Colonization

The Journal of Gene Medicine, Volume 28, Issue 9, September 2026.
In a hyperglycemic and inflammatory microenvironment, keratinocytes and macrophages upregulate S100A8. This activates the TLR4/NF‐κB pathway, leading to increased pro‐inflammatory cytokines (IL‐1β, TNF‐α, and IL‐6), reduced antimicrobial peptides (AMPs), impaired keratinocyte migration/proliferation, and enhanced S.
Qi Wang, Tong Sun, YanFei Xu, Li Zhang, Jiao Li, Lei Guo   +5 more
wiley   +1 more source

Structural basis for the differential recognition of integrin αvβ3 by rhodostomin and trimucrin. [PDF]

Commun Biol
Wang YT, Chang YT, Huang CH, Liau CT, Chen CY, Chuang WJ.   +5 more
europepmc   +1 more source

Heparan Sulfate Proteoglycans: Master Regulators of Cellular Signaling, Tissue Development, and Neural Function

Journal of Neuroscience Research, Volume 104, Issue 9, September 2026.
Ubiquitous cell‐associated, cytoplasmic, synaptic and extracellular matrix HS‐proteoglycans are multifunctional regulators of tissue form and function. HS‐proteoglycans have diverse functions as growth factor co‐receptors in cell proliferation, differentiation, tissue development, mechanical stabilization, synaptogenesis, synaptic plasticity, and ...
James Melrose
wiley   +1 more source

Integrin αvβ3 is a Potential Therapeutic Target in Cholangiocarcinoma. [PDF]

Int J Med Sci
Wulandari FS, Wang CY, Crawford DR, Yang YN, Then CK, Kumar S, Suk FM, Huang LY, Yang YS, Li ZL, Shih YJ, Tu HT, Wang K, Phu HD, Lin CM, Xuan DTM, Solomon DD, Lin HY, Whang-Peng J.   +18 more
europepmc   +1 more source

Next‐Generation Pluronic Micelles for Advanced Drug Delivery Application

Macromolecular Materials and Engineering, Volume 311, Issue 9, September 2026.
The present review provides a comprehensive overview of Pluronic‐based micelles for advanced drug and gene delivery. It highlights their structure, classification, synthesis, self‐assembly, and functionalization, as well as their biocompatibility and stimuli‐responsive properties.
Manoj Gundeti, Nithin Vidiyala, Shreya Dalvi, Rushikesh Girase, Sunil kumar Thota, Keshav Raj Paudel, Sathish Dyawanapelly   +6 more
wiley   +1 more source

IGF1 Binding to Integrin αvβ3 Induces Direct Gα13 Binding to IGF1R Kinase. [PDF]

Int J Mol Sci
Takada YK, Wu CY, Takada Y.
europepmc   +1 more source