Results 71 to 80 of about 56,023 (262)

β1 integrin deletion in β1^Ost-ko mice.

, 2018
A. Immunofluorescence analysis of β1 integrin expression on wild-type and β1Ost-ko P4 mice sections (cb: cortical bone; bm: bone marrow; dash line represents cortical the bone surface; arrows show osteoblasts deleted of β1 integrins; scale bar represents
Anne-Sophie Ribba (5125589), Molly Brunner (4013474), Marc R. Block (819163), Thierry Gautier (2708695), Genevieve Chevalier (5125586), Philippe Guardiola (280982), Daniel Bouvard (819161), Noémie Mandier (5125592)   +7 more
core   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

C1GALT1 modifies O-glycans on integrin β1.

, 2014
(a) Integrin β1 carried O-glycans in HCC cells. Lysates of HA22T cells (0.5 mg) were treated with neuraminidase (Neu) and/or PNGaseF and then pulled down (PD) by PNA agarose beads.
I-Rue Lai (608592), Yao-Ming Wu (386205), Chia-Hua Chen (234886), Hong-Shiee Lai (301362), Min-Chuan Huang (281425), Rey-Heng Hu (135326), Chiung-Hui Liu (291005), Miao-Juei Huang (281421)   +7 more
core   +1 more source

Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels

Advanced Healthcare Materials, EarlyView.
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa, Lineta Stonkute, Sara Trujillo, Mariana Azevedo Gonzalez Oliva, Francis Burton, Matthew J. Dalby, Oana Dobre, Godfrey Smith, Manuel Salmeron‐Sanchez   +8 more
wiley   +1 more source

Polymeric siRNA delivery targeting integrin-β1 could reduce interactions of leukemic cells with bone marrow microenvironment

Biomaterials and Biosystems, 2021
Uncontrolled proliferation of the myeloid cells due to BCR-ABL fusion has been successfully treated with tyrosine kinase inhibitors (TKIs), which improved the survival rate of Chronic Myeloid Leukemia (CML) patients.
Daniel Nisakar Meenakshi Sundaram, Cezary Kucharski, Remant Bahadur KC, Ibrahim Oğuzhan Tarman, Hasan Uludağ   +4 more
doaj   +1 more source

Use of a β1 Integrin-deficient Human T Cell to Identify β1 Integrin Cytoplasmic Domain Sequences Critical for Integrin Function

, 1998
T cell activation rapidly and transiently regulates the functional activity of integrin receptors. Stimulation of CD3/T cell receptor, CD2 or CD28, as well as activation with phorbol esters, can induce within minutes an increase in β1 integrin-mediated ...
Nadine C. Romzek, Elizabeth Hasse, Yoji Shimizu, Jeffrey Skronek, Pamela J. Reynolds, Estelle S. Harris, Cheryl L. Dell, Stephen W. Hunt   +7 more
core   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Development of a Synthetic Hydrogel to Foster Microvascularization of an Endometriosis Microphysiological System

Advanced Healthcare Materials, EarlyView.
ABSTRACT The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...
Lauren Pruett, Laura Bahlmann, Ryan Ogi, Angela Jiao, Priyatanu Roy, Matthew Johnson, David Trumper, Linda Griffith   +7 more
wiley   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Regulation of trophoblast beta1-integrin expression by contact with endothelial cells

Cell Communication and Signaling, 2004
Background In human and non-human primates, migratory trophoblasts penetrate the uterine epithelium, invade uterine matrix, and enter the uterine vasculature. Invasive trophoblasts show increased expression of β1 integrin.
Thirkill Twanda L, Hendren Sonia R, Soghomonians Arlen, Mariano Natalie F, Barakat Abdul I, Douglas Gordon C   +5 more
doaj   +1 more source