Results 281 to 290 of about 332,508 (311)

Measurement of Type I Interferon Production

Current Protocols in Immunology, 2011
AbstractThe Basic Protocol in this unit describes measurement of murine interferon (IFN)α/β by intracellular staining for these cytokines and detection by flow cytometry. Alternate protocols detail an enzyme‐linked immunoabsorbent assay (ELISA) for IFNα and a biological assay to measure IFN.
Rosalind E, Seeds, Joanna L, Miller
openaire   +2 more sources

The Role of Type I Interferon Subtypes and Interferon-Gamma in Type I Interferon Diabetes Inhibitory Activity in the NOD Mouse

Journal of Interferon & Cytokine Research, 2016
As in bacterial infections and endotoxin shock, type I interferons (IFNs) also have complex and often opposing effects in various models of autoimmune disease. We have shown that type I IFN paradoxically inhibits autoimmune diabetes in the nonobese diabetic mouse (NOD) and biobreeding (BB) rat.
Douglas, Sobel, Behrouz, Ahvazi, Carol, Pontzer   +2 more
openaire   +2 more sources

[Type I interferons].

Virologie (Montrouge, France)
Type I interferons (IFNa/b) form a family of related cytokines that include INFa, b, e/s, j, x (human) and limitin (mouse). These cytokines exert a potent antiviral activity, control cell proliferation and modulate the immune response. They are used in the fight against viral infections, tumors, and multiple sclerosis.
S, Delhaye, S, Paul, C, Sommereyns, V, Van Pesch, T, Michiels   +4 more
openaire   +1 more source

EMSY inhibits homologous recombination repair and the interferon response, promoting lung cancer immune evasion

Cell, 2022
Antonio Marzio, Emma Kurz, Jennifer M Sahni   +2 more
exaly  

SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

Cell, 2020
Carly G K Ziegler, Samuel J Allon, Vincent N Miao   +2 more
exaly  

The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity

Immunity, 2022
Mengdi Guo, Heidi J Elsaesser, Bryan E Snow   +2 more
exaly  

Alpha and Beta Type 1 Interferon Signaling: Passage for Diverse Biologic Outcomes

Cell, 2016
Juan L Mendoza, K Christopher Garcia, Michael B A Oldstone   +2 more
exaly  

Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade

Cell, 2019
Joseph L Benci, Ruth Choa, Yuanming Xu
exaly  

Inactivation of Interferon Receptor Promotes the Establishment of Immune Privileged Tumor Microenvironment

Cancer Cell, 2017
Kanstantsin V Katlinski, Angelica Ortiz, Sabyasachi Bhattacharya   +2 more
exaly  

Randomised trial of interferon α2b plus ribavirin for 48 weeks or for 24 weeks versus interferon α2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus

Lancet, The, 1998
Thierry Poynard, C Niederau, Gaetano Ideo   +2 more
exaly