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The Interactions Between Cancer Stem Cells and the Innate Interferon Signaling Pathway [PDF]
Frontiers in Immunology, 2020 Interferons (IFNs) form a family of cytokines with pleiotropic effects that modulate the immune response against multiple challenges like viral infections, autoimmune diseases, and cancer. While numerous anti-tumor activities have been described for IFNs,
Laura Martin-Hijano +5 more
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Intracellular interferons in fish : a unique means to combat viral infection [PDF]
, 2013 Peer reviewedPublisher ...
A Lopez-Munoz +45 more
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The use of intranasal interferon for prevention and treatment of acute respiratory infections
Aktualʹnaâ Infektologiâ, 2021 Interferons are cytokines that are produced by immunocompetent cells in response to the invasion of an infectious factor. The most important biological effect of interferons used in clinical practice is their ability to nonspecifically inhibit viral ...
S.О. Kramarov, V.V. Yevtushenko
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Interferons—Implications in the Immune Response to Respiratory Viruses
Microorganisms, 2023 Interferons (IFN) are an assemblage of signaling proteins made and released by various host cells in response to stimuli, including viruses. Respiratory syncytial virus (RSV), influenza virus, and SARS-CoV-2 are major causes of respiratory disease that ...
Harrison C. Bergeron +2 more
doaj +1 more source
Pro-inflammatory signaling by IL-10 and IL-22: bad habit stirred up by interferons? [PDF]
, 2013 Interleukin (IL)-10 and IL-22 are key members of the IL-10 cytokine family that share characteristic properties such as defined structural features, usage of IL-10R2 as one receptor chain, and activation of signal transducer and activator of ...
Mühl, Heiko
core +5 more sources
COVID-19 newer and emerging treatment options
Apollo Medicine, 2021 Coronavirus disease-19 is a highly contagious disease caused by severe acute respiratory syndrome coronavirus-2. It has shown a debilitating and catastrophic effect on the world population and is emerging as a challenging global health crisis, resulting ...
Suneetha Narreddy, Sneha Varahala
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Cell-cycle-gated feedback control mediates desensitization to interferon stimulation
eLife, 2020 Cells use molecular circuits to interpret and respond to extracellular cues, such as hormones and cytokines, which are often released in a temporally varying fashion.
Anusorn Mudla +9 more
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Interferons: Tug of War Between Bacteria and Their Host
Frontiers in Cellular and Infection Microbiology, 2021 Type I and III interferons (IFNs) are archetypally antiviral cytokines that are induced in response to recognition of foreign material by pattern recognition receptors (PRRs).
Noémie Alphonse +3 more
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Frontiers in Immunology, 2021 In mammals, the relationship between the immune system and behavior is widely studied. In fish, however, the knowledge concerning the brain immune response and behavioral changes during brain viral infection is very limited.
Miriam Mojzesz +11 more
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IFNα and IFNγ Impede Marek’s Disease Progression [PDF]
, 2019 Marek’s disease virus (MDV) is an alphaherpesvirus that causes Marek’s disease, a malignant lymphoproliferative disease of domestic chickens. While MDV vaccines protect animals from clinical disease, they do not provide sterilizing immunity and allow ...
Bertzbach, Luca D. +6 more
core +1 more source