Results 21 to 30 of about 171,612 (313)
mBio, 2022 As a result of the ongoing virus-host arms race, viruses have evolved numerous immune subversion strategies, many of which are aimed at suppressing the production of type I interferons (IFNs).
Tate Tabtieng +4 more
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Immuno, 2022 The pathogenesis of COVID-19 is complicated by immune dysfunction. The impact of immune-based therapy in COVID-19 patients has been well documented, with some notable studies on the use of anti-cytokine medicines.
Deepshikha Yadav +12 more
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Immunity, Inflammation and Disease, 2018 Background Mast cells are resident immune effector cells, often studied in the context of allergic disease. Found in substantial numbers at sites of potential infection they are increased at sites of angiogenesis and can be pivotal for the sensing and ...
Sharon A. Oldford +6 more
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Innate Immune Sensing of Viruses and Its Consequences for the Central Nervous System
Viruses, 2021 Viral infections remain a global public health concern and cause a severe societal and economic burden. At the organismal level, the innate immune system is essential for the detection of viruses and constitutes the first line of defense.
Hina Singh, Jeffrey Koury, Marcus Kaul
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Hepatitis C Virus Infection: Host–Virus Interaction and Mechanisms of Viral Persistence
Cells, 2019 Hepatitis C (HCV) is a major cause of liver disease, in which a third of individuals with chronic HCV infections may develop liver cirrhosis. In a chronic HCV infection, host immune factors along with the actions of HCV proteins that promote viral ...
DeGaulle I. Chigbu +4 more
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African Swine Fever Virus Infection and Cytokine Response In Vivo: An Update
Viruses, 2023 African swine fever (ASF) is a hemorrhagic viral disease of domestic pigs and wild suids (all Sus scrofa) caused by the ASF virus (ASFV). The disease is spreading worldwide without control, threatening pig production due to the absence of licensed ...
Giulia Franzoni +2 more
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Efficacy of oseltamivir treatment in influenza virus-infected obese mice
mBio, 2023 Obesity has been epidemiologically and empirically linked with more severe diseases upon influenza infection. To ameliorate severe disease, treatment with antivirals, such as the neuraminidase inhibitor oseltamivir, is suggested to begin within days of ...
Rebekah Honce +10 more
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Treatment of hepatitis C virus infection: From therapy with interferon to direct-acting antivirals
Iatreia, 2023 Hepatitis C virus (HCV) infection is a global public health concern. An estimated of 58 million people with chronic HCV infection are at risk of developing cirrhosis or hepatocellular carcinoma.
Laura Lopera +4 more
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eLife, 2023 DUX4 activates the first wave of zygotic gene expression in the early embryo. Mis-expression of DUX4 in skeletal muscle causes facioscapulohumeral dystrophy (FSHD), whereas expression in cancers suppresses IFNγ induction of major histocompatibility ...
Amy E Spens +4 more
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Animals, 2019 Heat stress significantly impacts the immunity and cytokine expression of chickens. However, the effects of embryonic thermal manipulation (TM) on cytokine expression in broiler chickens (broilers) is unclear.
Khaled M. M. Saleh +1 more
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