Results 1 to 10 of about 633,289 (295)

Targeting of interleukin-10 receptor by a potential human interleukin-10 peptide efficiently blocks interleukin-10 pathway-dependent cell proliferation

open access: yesTzu Chi Medical Journal, 2020
Objective: Human interleukin-10 (IL-10) is a dimeric and pleiotropic cytokine that plays a crucial role in cellular immunoregulatory responses. As IL-10 binds to its receptors, IL-10Ra and IL-10Rb, it will suppress or induce the downstream cellular ...
Chun-Chun Chang   +5 more
doaj   +4 more sources

Comparison of Serum Interleukin 10 Levels between Leprosy and Non-Leprosy Population

open access: yesMutiara Medika, 2021
Leprosy is a chronic granulomatous infectious disease that attacks the peripheral nerves, skin, and other organs. The cytokine IL-10 can deactivate macrophages, inhibit IL-12 production, which also inhibits IFN-ϒ production. IL-10 directly inhibits CD4+T
Adika Kodrati, Eddy Mart Salim, Zen Hafy
doaj   +1 more source

The perspectives of interleukin-10 in the pathogenesis and therapeutics of multiple myeloma

open access: yesTzu Chi Medical Journal, 2021
Multiple myeloma (MM) is typically featured by the increased levels of inflammatory cytokines in the neoplastic plasma cells (PCs) producing monoclonal immunoglobulin.
Cheng-Der Liu   +2 more
doaj   +1 more source

Interleukin 10 and interleukin 10 receptor in paediatric inflammatory bowel disease: from bench to bedside lesson

open access: yesJournal of Inflammation, 2021
Background The differences between adults and children in inflammatory bowel disease (IBD) phenotype, severity, complications, co-morbidities, and response to the therapy resulted in the extraction of paediatric IBD.
Paulina Krawiec   +2 more
doaj   +1 more source

Serum levels of interleukin-10 and its receptor in the multiple myeloma type I patients [PDF]

open access: yesJournal of Research in Applied and Basic Medical Sciences, 2023
Background & Aims: Multiple myeloma is a malignancy of plasma cells that is associated with high morbidity rate. Inflammation is a common feature in malignancy and plays a pivotal role in the cancer pathogenesis.
Mehdi Rajabzadeh   +4 more
doaj  

Role of interleukin 1β and interleukin 10 variants on ocular toxoplasmosis in Brazilian individuals

open access: yesFrontiers in Ophthalmology, 2023
IntroductionOcular toxoplasmosis (OT) is an intraocular inflammation caused by Toxoplasma gondii infection that affects the retina and choroid, giving rise to posterior uveitis.
Warlen Miiller Rocha Araujo   +12 more
doaj   +1 more source

IDENTIFICATION OF -2849 IL-10 GENE PROMOTER POLYMORPHISM IN LEPROSY PATIENT

open access: yesJurnal Kedokteran dan Kesehatan, 2022
Leprosy is a chronic granulomatous disease. Leprosy is caused by M. leprae. However, not all exposure to M. leprae causes the disease. The condition of the host immune system determines the pathogenesis of leprosy.
Desi Oktariana   +2 more
doaj   +1 more source

Correlation Between Interleukin 6 and Interleukin 10 in Acute Myocardial Infarction

open access: yesBiomolecules & Biomedicine, 2009
The aim of this study was to analyze (i) ratios between pro-inflammatory cytokines interleukin 6 (IL-6), interleukin 1 (IL-1), tumour necrosis factor α (TNF-α) and anti-inflammatory cytokine interleukin 10 (IL-10) in patients with acute myocardial ...
Larisa Dizdarević-Hudić   +9 more
doaj   +1 more source

Interleukin – 17 and interleukin-10 as inflammatory and prevention biomarkers in periimplant diseases

open access: yesInternational Journal of Preventive Medicine, 2019
Background: Periimplant diseases are inflammatory diseases. Thus, the level of preinflammatory cytokines which has important role in the inflammation processes can consider as biomchemical markers for early diagnosis and prevention of periimplant ...
Shirin Zahra Farhad   +2 more
doaj   +1 more source

Study on relationship between elderly sarcopenia and inflammatory cytokine IL-6, anti-inflammatory cytokine IL-10

open access: yesBMC Geriatrics, 2018
Background and objectives The pathophysiological mechanism of sarcopenia in the elderly has not yet been fully understood. Here, we aim to explore the relationship between sarcopenia and the inflammatory cytokine interleukin-6 (IL-6), and the anti ...
Yu-Dong Rong   +4 more
doaj   +1 more source

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