Results 1 to 10 of about 10,723,036 (376)
Neuroprotective effects of interleukin 10 in spinal cord injury [PDF]
Frontiers in Molecular Neuroscience, 2023 Spinal cord injury (SCI) starts with a mechanical and/or bio-chemical insult, followed by a secondary phase, leading progressively to severe collapse of the nerve tissue.
Juan Li +7 more
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Recombinant Interleukin 10 [PDF]
Definitions, 2020 A recombinant cytokine chemically identical to or similar to interleukin-10 (IL-10) secreted by certain leukocytes with immunomodulatory activities. IL-10 is an anti-inflammatory cytokine, capable of inhibiting synthesis of pro-inflammatory cytokines ...
openaire +2 more sources
Comparison of Serum Interleukin 10 Levels between Leprosy and Non-Leprosy Population
Mutiara Medika, 2021 Leprosy is a chronic granulomatous infectious disease that attacks the peripheral nerves, skin, and other organs. The cytokine IL-10 can deactivate macrophages, inhibit IL-12 production, which also inhibits IFN-ϒ production. IL-10 directly inhibits CD4+T
Adika Kodrati, Eddy Mart Salim, Zen Hafy
doaj +1 more source
Nature Communications, 2022 Despite recent advances in cancer immunotherapy, certain tumor types, such as Glioblastomas, are highly resistant due to their tumor microenvironment disabling the anti-tumor immune response.
V. Ravi +27 more
semanticscholar +1 more source
The perspectives of interleukin-10 in the pathogenesis and therapeutics of multiple myeloma
Tzu Chi Medical Journal, 2021 Multiple myeloma (MM) is typically featured by the increased levels of inflammatory cytokines in the neoplastic plasma cells (PCs) producing monoclonal immunoglobulin.
Cheng-Der Liu +2 more
doaj +1 more source
Structure-based decoupling of the pro- and anti-inflammatory functions of interleukin-10
Science, 2021 Cryo-EM helps engineer enhanced IL-10 Interleukin-10 (IL-10) binds to the IL-10 receptor (IL-10R), comprising two high-affinity α chains and two low-affinity β chains.
R. A. Saxton +8 more
semanticscholar +1 more source
Journal of Inflammation, 2021 Background The differences between adults and children in inflammatory bowel disease (IBD) phenotype, severity, complications, co-morbidities, and response to the therapy resulted in the extraction of paediatric IBD.
Paulina Krawiec +2 more
doaj +1 more source
Immunohistochemistry Analysis in Inflammatory Bowel Disease-Should We Bring to Light Interleukin-10? [PDF]
BiomedicinesPavel C +12 more
europepmc +2 more sources
Serum levels of interleukin-10 and its receptor in the multiple myeloma type I patients [PDF]
Journal of Research in Applied and Basic Medical Sciences, 2023 Background & Aims: Multiple myeloma is a malignancy of plasma cells that is associated with high morbidity rate. Inflammation is a common feature in malignancy and plays a pivotal role in the cancer pathogenesis.
Mehdi Rajabzadeh +4 more
doaj