Results 11 to 20 of about 655,029 (238)

Comparison of spleen characterization and plasma levels of interleukin 6 and 10 in obese and healthy individuals [PDF]

open access: yesJournal of Shahrekord University of Medical Sciences
Background and aims: Spleen is one of the organs that has great importance in Iranian traditional medicine due to its relationship with obesity. Therefore, in this study, we aim to investigate spleen characterization and plasma levels of interleukin 6 ...
Mahdis Tanzifi   +4 more
doaj   +1 more source

Biology of interleukin-10 [PDF]

open access: yesCytokine & Growth Factor Reviews, 2010
Interleukin (IL)-10 is the most important cytokine with anti-inflammatory properties besides TGF-β and IL-35. It is produced by activated immune cells, in particular monocytes/macrophages and T cell subsets including Tr1, Treg, and Th1 cells. IL-10 acts through a transmembrane receptor complex, which is composed of IL-10R1 and IL-10R2, and regulates ...
Sabat R   +6 more
openaire   +2 more sources

Macrophage dysfunction initiates colitis during weaning of infant mice lacking the interleukin-10 receptor

open access: yeseLife, 2017
Infants with defects in the interleukin 10 receptor (IL10R) develop very early onset inflammatory bowel disease. Whether IL10R regulates lamina propria macrophage function during infant development in mice and whether macrophage-intrinsic IL10R signaling
Naresh S Redhu   +16 more
doaj   +1 more source

Blood concentrations of endothelin, interleukins 6 and 10 in men with diabetes mellitus

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2021
Background. Pathological activation of cytokines is one of the key links in the pathogenesis of diabetes mellitus (DM) and the development of its complications, in particular from the cardiovascular system.
E.V. Luchytskiy   +4 more
doaj   +1 more source

Mapping of the interleukin‐10/interleukin‐10 receptor combining site [PDF]

open access: yesProtein Science, 1998
AbstractThe discontinuous interleukin‐10(IL‐10)/interleukin‐10 receptor (IL‐10R) combining site was mapped using sets of overlapping peptides derived from both binding partners bound to continuous cellulose membranes. Low affinity binding of single regions of the discontinuous contact sites on IL‐10 and IL‐10R could be identified due to (1) high ...
U, Reineke   +3 more
openaire   +2 more sources

Cytokine profiling for Egyptian diabetic patients with nephropathy

open access: yesJournal of Medicine in Scientific Research, 2022
Background Evidence suggests that poor glycemic control is significantly associated with the development of microvascular complications of diabetes such as nephropathy.
Samar M Samir   +3 more
doaj   +1 more source

The Correlation between Interleukin-10 Serum with Bacterial Index in Multidrug Therapy-treated Leprosy Patients

open access: yesBerkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2016
Background: Immune respons disturbance oftenly found in leprosy patient, mainly in various T cell subset and cytokine immune system arranger. Interleukin-10 produced by Th 2 cell, Th3 cell, monocyte, dendritic cell, eosinophil, mast cell, and ...
Eva Krishna Sutedja   +2 more
doaj   +1 more source

Interleukin 10 And 18 levels in Essential Hypertensive

open access: yesJournal of Applied Sciences and Environmental Management, 2019
The mechanism underlying a sustained blood pressure elevation and its sequelae on the inflammatory cascades have not been totally unraveled. This research was, in addition to body mass index (BMI), systolic and diastolic blood pressure (SBP and DBP ...
O.O. Odewusi, H.B. Osadolor
doaj   +1 more source

Neuroprotective effects of interleukin 10 in spinal cord injury

open access: yesFrontiers in Molecular Neuroscience, 2023
Spinal cord injury (SCI) starts with a mechanical and/or bio-chemical insult, followed by a secondary phase, leading progressively to severe collapse of the nerve tissue.
Juan Li   +7 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

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