Results 191 to 200 of about 583,184 (351)

High levels of Interleukin - 13 in patients with scrub typhus correlate with disease severity. [PDF]

Sci Rep
Chen Y, Li J, Ma X, He Y, Wu X, Zhu W, Qin P, Fang L, Wei Y, Li J.   +9 more
europepmc   +1 more source

De Novo Design and Directed Evolution Refinement of Mirror‐Image Protein Binders Targeting Interleukin‐4

Advanced Science, EarlyView.
This study presents the de novo design and directed evolution of a mirror‐image D‐protein inhibitor targeting human interleukin‐4 (IL‐4). The engineered molecule exhibits nanomolar binding affinity for IL‐4 and effectively inhibits IL‐4–mediated signaling.
Liqing Xu, Yuxiang Ren, Tongyue Wang, Hongyong Li, Yue Yao, Lei Liu, Ke Sun, Peilong Lu   +7 more
wiley   +1 more source

Interleukin 13 (IL-13) Signalling as a Potential Target for Cell Therapies in Liver Fibrosis. [PDF]

Int J Mol Sci
Mazurski A, Bednarz A, Czekaj P.
europepmc   +1 more source

Mechanostimulatory Cues Determine Intestinal Fibroblast Fate and Profibrotic Remodeling in a Physiodynamic Human Gut‐on‐a‐Chip

Advanced Science, EarlyView.
A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min, Nam Than, Yong Cheol Shin, Elif G. Ertugral, Chandrasekhar R. Kothapalli, Olumuyiwa Awoniyi, Hyun Jung Kim   +6 more
wiley   +1 more source

NF45 and NF90 Regulate HS4-dependent Interleukin-13 Transcription in T Cells [PDF]

, 2010
Patricia Kiesler, Paul A. Haynes, Lingfang Shi, Peter N. Kao, Vicki H. Wysocki, Donata Vercelli   +5 more
openalex   +1 more source

Unveiling the role of interleukin-13 in liver fibrosis of chronic hepatitis B patients: Development of a predictive model. [PDF]

PLoS One
Bestari MB, Wijaya MP, Girawan D, Agustanti N, Nugraha ES.   +4 more
europepmc   +1 more source

CRP Deficiency Rescues Periodontitis‐Induced Hippocampal Neurogenesis Impairment by Suppressing OPC‐Derived BMP4 Signaling in Rats

Advanced Science, EarlyView.
Chronic periodontitis elevates circulating CRP, which enters the hippocampus to upregulate BMP4 in oligodendrocyte precursor cells (OPCs), thereby impairing neurogenesis and inducing anxiety/depression‐like behaviors in rats. Counteracting this pathway, CRP deficiency helps confer functional resilience to OPCs.
Lingjie Li, Ping Deng, Siyu Hou, Xianbo Xia, Wei Zhao, Xingyu Zhu, Yang Zhang, Chao Wang, Ling Xu, Jinlin Song   +9 more
wiley   +1 more source

The less‐known face of dupilumab: its role in mesenchymal stem cells by interleukin‐13 modulation

, 2021
Anna Campanati, Mariangela Di Vincenzo, Giulia Radi, Giulio Rizzetto, Gianluca Carnevale, Saverio Marchi, Monia Orciani, Annamaria Offidani   +7 more
openalex   +2 more sources

Significant Contributions of Interleukin-13 Genotypes to Asthma Severity. [PDF]

In Vivo
Shen TC, Chen GL, Chen LH, Wang YC, Shih HY, Yang YC, Tsai CW, Chang WS, Hsia TC, Bau DT.   +9 more
europepmc   +1 more source

Serum Interleukin-13 and Caspase 8 are Elevated in Prurigo Nodularis. [PDF]

Acta Derm Venereol, 2023
Ju T, Labib A, Nattkemper L, Engle S, Auxier A, Hahn N, Sissons S, Sims JT, Sun Z, Okragly AJ, Yosipovitch G.   +10 more
europepmc   +1 more source