Results 11 to 20 of about 3,159,504 (378)
Interleukin‐17 regulates matrix metalloproteinase activity in human pulmonary tuberculosis [PDF]
Journal of Pathology, 2018 Tuberculosis (TB) is characterized by extensive pulmonary matrix breakdown. Interleukin‐17 (IL‐17) is key in host defence in TB but its role in TB‐driven tissue damage is unknown.
Shivani Singh +6 more
semanticscholar +3 more sources
Applied Sciences, 2022 Background: Periodontitis (P) is a chronic inflammatory disease characterized by the destruction of periodontium support tissue generated by different immuno-inflammatory mechanisms, including the RANK/RANKL/OPG and the IL-23/IL-17 axis.
Ruth Rodríguez-Montaño +7 more
doaj +1 more source
Interleukin-17 governs hypoxic adaptation of injured epithelium
Science, 2022 Mammalian cells autonomously activate hypoxia-inducible transcription factors (HIFs) to ensure survival in low-oxygen environments. We report here that injury-induced hypoxia is insufficient to trigger HIF1α in damaged epithelium.
P. Konieczny +15 more
semanticscholar +1 more source
Interleukin-17: A Social Cytokine [PDF]
Cell, 2020 Some children with autism spectrum disorder (ASD) show behavioral improvements when experiencing inflammation accompanied by fever; however, little is known about the mechanisms that underlie these beneficial effects. In a recent issue of Nature, Reed and colleagues demonstrate that the production of interleukin-17 (IL-17) during inflammation promotes ...
Hoogenraad, Casper C. +1 more
openaire +4 more sources
Interleukin-17 Family Cytokines in Metabolic Disorders and Cancer
Genes, 2022 Interleukin-17 (IL-17) family cytokines are potent drivers of inflammatory responses. Although IL-17 was originally identified as a cytokine that induces protective effects against bacterial and fungal infections, IL-17 can also promote chronic ...
E. Meehan, Kepeng Wang
semanticscholar +1 more source
Interleukin-17 family members in health and disease
International Immunology, 2021 The interleukin-17 (IL-17) family consists of six family members (IL-17A–IL-17F) and all the corresponding receptors have been identified recently.
S. Chung, Xiaoxiao Ye, Y. Iwakura
semanticscholar +1 more source
Interleukin-17 Cytokines and Receptors: Potential Amplifiers of Tendon Inflammation
Frontiers in Bioengineering and Biotechnology, 2021 Interleukin (IL)-17A, a pro-inflammatory cytokine that is linked to the pathology of several inflammatory diseases, has been shown to be upregulated in early human tendinopathy and to mediate inflammatory and tissue remodelling events.
Jolet Y. Mimpen +3 more
doaj +1 more source
Interleukin‐17—A multifaceted cytokine in viral infections
Journal of Cellular Physiology, 2021 Viral infections are a major threat to the human population due to the lack of selective therapeutic measures. The morbidity and mortality reported worldwide are very alarming against viral pathogens. The proinflammatory environment is required for viral
Utkarsha Sahu +5 more
semanticscholar +1 more source
Dermatologic Therapy, 2021 Psoriasis is an immune-mediated inflammatory skin disease associated with numerous inflammatory comorbidities, including increased cardiovascular risk.
A. Menter +5 more
semanticscholar +1 more source
Interleukin-17: A Revisited Study [PDF]
International Journal of Immunopathology and Pharmacology, 2004 Cytokine is a term used for a large group of proteins that are produced by a variety of cells in the body and act to stimulate, or inhibit, the functions of the same cells that produce them or of other cell types. The IL-17 family members are different in expressions and proinflammatory responses.
HUANG SH +14 more
openaire +4 more sources