Results 1 to 10 of about 579,902 (183)
Journal of Leukocyte Biology, 2003 Interleukin-18 (IL-18), a recently described member of the IL-1 cytokine superfamily, is now recognized as an important regulator of innate and acquired immune responses.
Gracie, J.A. +2 more
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Interleukin 18 in the CNS [PDF]
Journal of Neuroinflammation, 2010 Interleukin (IL)-18 is a cytokine isolated as an important modulator of immune responses and subsequently shown to be pleiotropic. IL-18 and its receptors are expressed in the central nervous system (CNS) where they participate in neuroinflammatory ...
Sugama Shuei +3 more
doaj +5 more sources
Interleukin-18 and interleukin-18 Binding Protein
Frontiers in Immunology, 2013 Interleukin-18 (IL 18) is a member of the IL 1 family of cytokines. Increasing reports have expanded the role of IL 18 in mediating inflammation in animal models of disease using IL 18 deficient mice, neutralization of IL 18 or deficiency in the IL 18 ...
Charles eDinarello +6 more
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The role of interleukin-18 and interleukin-18 binding protein in K/BxN serum transfer-induced arthritis [PDF]
Frontiers in Immunology, 2023 BackgroundInterleukin-18 is a proinflammatory cytokine, the activity of which is regulated by its natural inhibitor, IL-18 binding protein (IL-18BP). Elevated circulating levels of IL-18 have been observed in patients with systemic juvenile idiopathic ...
Sebastien Fauteux-Daniel +17 more
doaj +3 more sources
Interleukin-18 in Inflammatory Kidney Disease [PDF]
Frontiers in Medicine, 2021 Interleukin (IL)-18, a member of the IL-1 superfamily, is a pro-inflammatory cytokine that is structurally similar to IL-1β. IL-18 promotes the production of interferon gamma (IFN-γ) and strongly induces a Th1 response.
Yasuaki Hirooka, Yuji Nozaki
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Proinflammatory cytokines interleukin-18 and interleukin-6 mediate anorexia induction by trichothecene deoxynivalenol and its congeners [PDF]
Frontiers in Veterinary ScienceAs the common foodborne mycotoxins with the highest pollution rate, deoxynivalenol (DON, also named “vomitoxin”) can harm the health of humans and animals by causing anorectic response.
Chuang Zhou +8 more
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Serum interleukin 18 level in kidney diseases and age [PDF]
Urology AnnalsBackground: Interleukin-18 (IL-18), also known as interferon-gamma inducing factor is a protein which in humans is encoded by the IL18 gene, it is a member of the IL 1 family and has a molecular weight of 18 kDa.
Ghada Abd Eltawab Radwan +2 more
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Association of Interleukin-18 gene polymorphism -137G/C with Allergic rhinitis [PDF]
مجله دانشگاه علوم پزشکی گرگان, 2015 Background and Objective: The interleukin-18 (IL-18) gene on chromosome 11 has been suggested as a susceptibility factor for allergies. It is a member of the IL-1 family that was originally described as interferon (IFN-γ)–inducing factor.
Ramazi Sh +5 more
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Interleukin 18 and interleukin 22 as important immune markers in patients with tuberculosis [PDF]
E3S Web of Conferences, 2023 Tuberculosis (TB) is a lung infection caused by the bacterium Mycobacterium tuberculosis (MTB). TB is a leading cause of death globally, accounting for approximately 1.5 million deaths per year.
Kamoona Firas Mohammad Hussein +1 more
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Interleukin 18 in Immune-mediated rheumatic diseases and COVID-19
Научно-практическая ревматология, 2022 Immune-mediated rheumatic diseases (IMRDs), based on the leading mechanisms of pathogenesis, are conditionally classified into autoimmune, autoinflammatory, and «mixed pattern».
E. L. Nasonov, A. S. Avdeeva
doaj +1 more source