Results 1 to 10 of about 17,429 (49)

Extracting Mutual Interaction Rules Using Fuzzy Structured Agent-based Model of Tumor-Immune System Interactions [PDF]

open access: yesJournal of Biomedical Physics and Engineering, 2021
Background: There are many studies to investigate the effects of each interacting component of tumor-immune system interactions. In all these studies, the distinct effect of each component was investigated.
A Allahverdy   +7 more
doaj   +1 more source

The IL-2 – IL-2 receptor pathway: Key to understanding multiple sclerosis

open access: yesJournal of Translational Autoimmunity, 2021
The development, progression, diagnosis and treatment of autoimmune diseases, such as multiple sclerosis (MS), are convoluted processes which remain incompletely understood. Multiple studies demonstrated that the interleukin (IL)-2 – IL-2 receptor (IL-2R)
Daphne Peerlings   +2 more
doaj   +1 more source

Effects of ivermectin on cytokine and immunoglobulin levels in sheep

open access: yesRevista Colombiana de Ciencias Pecuarias, 2023
Background: Ivermectin may affect the levels of cytokines and immunoglobulins in sheep, considering that avermectins have an effect on the immune system.
Rahmi Canbar   +5 more
doaj   +1 more source

Pro- and Anti-Tumoral Factors Involved in Total Body Irradiation and Interleukin-2 Conditioning in Adoptive T Cell Therapy of Melanoma-Bearing Rag1 Knock-Out Mice

open access: yesCells, 2022
In adoptive T cell therapy (ACT), the transfer of tumor-specific T cells is paralleled by the conditioning regimen to increase therapeutic efficacy. Pre-conditioning depletes immune-suppressive cells and post-conditioning increases homeostatic signals to
Seon-Hee Kim   +4 more
doaj   +1 more source

Detection of Salivary Interleukin 2 and Interleukin 6 in Patients With Burning Mouth Syndrome

open access: yesMediators of Inflammation, 2006
The etiology of BMS remains unknown. Role of various cytokines has been implicated in the development of BMS. The aim of this study was to evaluate levels of salivary IL-2 and IL-6 in patients with BMS, compared with age-matched healthy volunteers ...
Daria Simcic   +5 more
doaj   +2 more sources

Low-dose IL-2 improved clinical symptoms by restoring reduced regulatory T cells in patients with refractory rheumatoid arthritis: A randomized controlled trial

open access: yesFrontiers in Immunology, 2022
BackgroundRegulatory T cells (Tregs) have been found to play crucial roles in immune tolerance. However, the status of Tregs in refractory rheumatoid arthritis (RA) is still unclear.
Jia Wang   +17 more
doaj   +1 more source

T Cells, Interleukin-2 and Systemic Lupus Erythematosus—From Pathophysiology to Therapy

open access: yesCells, 2022
The phenotypic and functional complexities of T cells engender complicated and often confusing concepts as to how T cells ignite, accelerate and brake the inflammatory processes involved in systemic lupus erythematosus (SLE), let alone the plasticity of ...
Anselm Mak
doaj   +1 more source

Low Dose Interleukin-2 Ameliorates Sjögren’s Syndrome in a Murine Model

open access: yesFrontiers in Medicine, 2022
Sjögren’s syndrome (SS) is a systemic autoimmune disease with no efficient treatment, and it is associated with dysregulated immune cells and impaired interleukin (IL)-2 signaling. IL-2 is critical for the development and maintenance of Treg cells.
Yifan Wang   +11 more
doaj   +1 more source

Distinct Expression of Inflammatory Features in T Helper 17 Cells from Multiple Sclerosis Patients

open access: yesCells, 2019
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS). T helper (Th) 17 lymphocytes play a role in the pathogenesis of MS.
Alessia Capone   +9 more
doaj   +1 more source

Retrospective Analysis of Pediatric Hepatoblastoma With Tumor Rupture: Experience From a Single Center

open access: yesFrontiers in Pediatrics, 2022
PurposeHepatoblastoma (HB) tumor rupture is currently considered as a high-risk factor in some risk stratification systems. This study aimed to investigate the value of HB tumor rupture in predicting the poor prognosis.MethodsThe clinical data from ...
Yu-Tong Zhang   +3 more
doaj   +1 more source

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