Results 1 to 10 of about 23,047,889 (226)
Retrospective analysis of sorafenib combined with interferon α-1b, interleukin-2, and thalidomide as maintenance therapy in FLT3-ITD-positive acute myeloid leukemia [PDF]
Frontiers in OncologyObjectiveTo evaluate the clinical efficacy of maintenance therapy with sorafenib combined with interferon α-1b, interleukin-2, and thalidomide (the ITI regimen) in patients with FLT3-ITD-positive acute myeloid leukemia (AML).Methods19 FLT3-ITD(+) AML ...
Cheng Cheng +5 more
doaj +2 more sources
The IL-2 – IL-2 receptor pathway: Key to understanding multiple sclerosis
Journal of Translational Autoimmunity, 2021 The development, progression, diagnosis and treatment of autoimmune diseases, such as multiple sclerosis (MS), are convoluted processes which remain incompletely understood. Multiple studies demonstrated that the interleukin (IL)-2 – IL-2 receptor (IL-2R)
Daphne Peerlings +2 more
doaj +1 more source
Extracting Mutual Interaction Rules Using Fuzzy Structured Agent-based Model of Tumor-Immune System Interactions [PDF]
Journal of Biomedical Physics and Engineering, 2021 Background: There are many studies to investigate the effects of each interacting component of tumor-immune system interactions. In all these studies, the distinct effect of each component was investigated.
A Allahverdy +7 more
doaj +1 more source
T Cells, Interleukin-2 and Systemic Lupus Erythematosus—From Pathophysiology to Therapy
Cells, 2022 The phenotypic and functional complexities of T cells engender complicated and often confusing concepts as to how T cells ignite, accelerate and brake the inflammatory processes involved in systemic lupus erythematosus (SLE), let alone the plasticity of ...
Anselm Mak
doaj +1 more source
Frontiers in Immunology, 2022 BackgroundRegulatory T cells (Tregs) have been found to play crucial roles in immune tolerance. However, the status of Tregs in refractory rheumatoid arthritis (RA) is still unclear.
Jia Wang +17 more
doaj +1 more source
Detection of Salivary Interleukin 2 and Interleukin 6 in Patients With Burning Mouth Syndrome
Mediators of Inflammation, 2006 The etiology of BMS remains unknown. Role of various cytokines has been implicated in the development of BMS. The aim of this study was to evaluate levels of salivary IL-2 and IL-6 in patients with BMS, compared with age-matched healthy volunteers ...
Daria Simcic +5 more
doaj +2 more sources
Low Dose Interleukin-2 Ameliorates Sjögren’s Syndrome in a Murine Model
Frontiers in Medicine, 2022 Sjögren’s syndrome (SS) is a systemic autoimmune disease with no efficient treatment, and it is associated with dysregulated immune cells and impaired interleukin (IL)-2 signaling. IL-2 is critical for the development and maintenance of Treg cells.
Yifan Wang +11 more
doaj +1 more source
Effects of ivermectin on cytokine and immunoglobulin levels in sheep
Revista Colombiana de Ciencias Pecuarias, 2023 Background: Ivermectin may affect the levels of cytokines and immunoglobulins in sheep, considering that avermectins have an effect on the immune system.
Rahmi Canbar +5 more
doaj +1 more source
Cells, 2022 In adoptive T cell therapy (ACT), the transfer of tumor-specific T cells is paralleled by the conditioning regimen to increase therapeutic efficacy. Pre-conditioning depletes immune-suppressive cells and post-conditioning increases homeostatic signals to
Seon-Hee Kim +4 more
doaj +1 more source
Journal of Experimental Medicine, 1998 Peripheral tolerance may be maintained by a population of regulatory/suppressor T cells that prevent the activation of autoreactive T cells recognizing tissue-specific antigens.
A. Thornton, E. Shevach
semanticscholar +1 more source