Results 1 to 10 of about 17,429 (49)
Extracting Mutual Interaction Rules Using Fuzzy Structured Agent-based Model of Tumor-Immune System Interactions [PDF]
Background: There are many studies to investigate the effects of each interacting component of tumor-immune system interactions. In all these studies, the distinct effect of each component was investigated.
A Allahverdy +7 more
doaj +1 more source
The IL-2 – IL-2 receptor pathway: Key to understanding multiple sclerosis
The development, progression, diagnosis and treatment of autoimmune diseases, such as multiple sclerosis (MS), are convoluted processes which remain incompletely understood. Multiple studies demonstrated that the interleukin (IL)-2 – IL-2 receptor (IL-2R)
Daphne Peerlings +2 more
doaj +1 more source
Effects of ivermectin on cytokine and immunoglobulin levels in sheep
Background: Ivermectin may affect the levels of cytokines and immunoglobulins in sheep, considering that avermectins have an effect on the immune system.
Rahmi Canbar +5 more
doaj +1 more source
In adoptive T cell therapy (ACT), the transfer of tumor-specific T cells is paralleled by the conditioning regimen to increase therapeutic efficacy. Pre-conditioning depletes immune-suppressive cells and post-conditioning increases homeostatic signals to
Seon-Hee Kim +4 more
doaj +1 more source
Detection of Salivary Interleukin 2 and Interleukin 6 in Patients With Burning Mouth Syndrome
The etiology of BMS remains unknown. Role of various cytokines has been implicated in the development of BMS. The aim of this study was to evaluate levels of salivary IL-2 and IL-6 in patients with BMS, compared with age-matched healthy volunteers ...
Daria Simcic +5 more
doaj +2 more sources
BackgroundRegulatory T cells (Tregs) have been found to play crucial roles in immune tolerance. However, the status of Tregs in refractory rheumatoid arthritis (RA) is still unclear.
Jia Wang +17 more
doaj +1 more source
T Cells, Interleukin-2 and Systemic Lupus Erythematosus—From Pathophysiology to Therapy
The phenotypic and functional complexities of T cells engender complicated and often confusing concepts as to how T cells ignite, accelerate and brake the inflammatory processes involved in systemic lupus erythematosus (SLE), let alone the plasticity of ...
Anselm Mak
doaj +1 more source
Low Dose Interleukin-2 Ameliorates Sjögren’s Syndrome in a Murine Model
Sjögren’s syndrome (SS) is a systemic autoimmune disease with no efficient treatment, and it is associated with dysregulated immune cells and impaired interleukin (IL)-2 signaling. IL-2 is critical for the development and maintenance of Treg cells.
Yifan Wang +11 more
doaj +1 more source
Distinct Expression of Inflammatory Features in T Helper 17 Cells from Multiple Sclerosis Patients
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS). T helper (Th) 17 lymphocytes play a role in the pathogenesis of MS.
Alessia Capone +9 more
doaj +1 more source
PurposeHepatoblastoma (HB) tumor rupture is currently considered as a high-risk factor in some risk stratification systems. This study aimed to investigate the value of HB tumor rupture in predicting the poor prognosis.MethodsThe clinical data from ...
Yu-Tong Zhang +3 more
doaj +1 more source

