Plasma interleukin-21 levels and genetic variants are associated with susceptibility to rheumatoid arthritis [PDF]
BMC Musculoskeletal Disorders, 2021 Background Rheumatoid Arthritis (RA) is a chronic inflammatory condition characterized by autoantibodies development and an elevated spectrum of pro-inflammatory cytokines.
Youguo Hao +5 more
doaj +2 more sources
The influence of black cumin seed oil therapy with dosage of 1.5 mL/day and 3 mL/day to interleukin-21 (IL-21) expression of the patients with metabolic syndrome risk [PDF]
, 2017 Metabolic syndrome (MS) is a metabolic disorder caused by obesity and insulin resistance. In the state of obesity and insulin resistance occurs increased fat metabolism that causes production reactive oxygen species (ROS) and oxidative stress that ...
Desi Reski Fajar +2 more
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Observational study of Interleukin-21 (IL-21) does not distinguish Kawasaki disease from other causes of fever in children [PDF]
Pediatric Rheumatology Online Journal, 2017 Background Kawasaki disease (KD) is a febrile childhood vasculitis of unknown etiology. The diagnosis is highly concerning as over a quarter of children who fail to receive timely treatment with intravenous immunoglobulin (IVIG) will develop coronary ...
Rachel Engelberg +3 more
doaj +2 more sources
Interleukin-21 and Interleukin-23 levels in familial Mediterranean Fever before and after treatment: the role of cytokines in disease pathogenesis [PDF]
Scientific ReportsIn a previous study, it has been shown that the population of Th17 lymphocytes was increased in patients with FMF. IL-21 and IL-23 play significant roles in the production and differentiation of Th17 cells.
Mutlu Hizal +7 more
doaj +2 more sources
Iranian Journal of Allergy, Asthma and Immunology, 2018 Cytokines have prominent roles in activating of different T cells and shifting the immune response, in this study the role of three cytokines (IL-21, IL-23 and IL-27) is investigated in the liver transplant rejection.
Afsoon Afshari +6 more
doaj +2 more sources
Interleukin-21 in Viral Infections. [PDF]
Int J Mol Sci, 2021 Interleukin (IL)-21 is a cytokine that affects the differentiation and function of lymphoid and myeloid cells and regulates both innate and adaptive immune responses. In addition to regulating the immune response to tumor and viral infections, IL-21 also has a profound effect on the development of autoimmune and inflammatory diseases. IL-21 is produced
Asao H.
europepmc +4 more sources
Interleukin 21 (IL-21) regulates chronic allograft vasculopathy (CAV) in murine heart allograft rejection. [PDF]
PLoS ONE, 2019 IL-21 is the most recently discovered common gamma-chain cytokine that promotes persistent T-cell responses in chronic infections, autoimmunity and cancer.
Mithun Khattar +6 more
doaj +2 more sources
IL21R (interleukin 21 receptor) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2012 Review on IL21R (interleukin 21 receptor), with data on DNA, on the protein encoded, and where the gene is implicated.
Silvano Ferrini, Marina Fabbi
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Relationship between Interleukin 21 and Activation of Natural Killer cells in Iraqi patients with CML [PDF]
Journal of Medical and Life ScienceBackground: CML is a persistent hematological malignancy, distinguished by aberrant white blood cell growth. It is caused by a genetic abnormality that leads to the uncontrolled production of a specific type of white blood cell called a chronic myeloid ...
Elaf Hmeed +5 more
doaj +2 more sources
Interleukin 21-Armed EGFR-VHH-CAR-T Cell Therapy for the Treatment of Esophageal Squamous Cell Carcinoma. [PDF]
BiomedicinesZhang C +6 more
europepmc +2 more sources