Results 41 to 50 of about 3,093,388 (334)
Fc-engineered anti-CD33 monoclonal antibody potentiates cytotoxicity of membrane-bound interleukin-21 expanded natural killer cells in acute myeloid leukemia. [PDF]
Cytotherapy, 2020 Mani R +9 more
europepmc +3 more sources
Higher interleukin 21 level is predictive of relapse in immune thrombocytopenia. Is it associated with activation of the complement system? [PDF]
British Journal of Haematology, 2015 Birsen Sahip +3 more
openalex +2 more sources
Evaluation of plasma IL-21 as a potential biomarker for type 1 diabetes progression
Frontiers in Immunology, 2023 IL-21 is a multifunctional cytokine linked with the pathophysiology of several autoimmune diseases, including type 1 diabetes. In this study, our aim was to examine plasma IL-21 levels in individuals at different stages of type 1 diabetes progression. We
Anna-Mari Schroderus +18 more
doaj +1 more source
Pathogens, 2022 Protective immunity against blood-stage Plasmodium infection and the disease malaria depends on antibodies secreted from high-affinity B cells selected during the germinal center (GC) response.
Fionna A. Surette, Noah S. Butler
doaj +1 more source
Frontiers in Immunology, 2021 ObjectivesT Follicular helper (Tfh) cells, recognized as a distinct CD4+ T cell subset, mediate the development of long-lived humoral immunity via B cell activation/differentiation. Tfh cells play an important role during hepatic viral infection, but its
Bingying Du +6 more
doaj +1 more source
Interleukin-21 sustains inflammatory signals that contribute to sporadic colon tumorigenesis [PDF]
, 2015 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.This work received ...
Colantoni, A +13 more
core +6 more sources
IL21R (interleukin 21 receptor) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on IL21R (interleukin 21 receptor), with data on DNA, on the protein encoded, and where the gene is implicated.
Ferrini, S, Fabbi, M
openaire +5 more sources
Definitions, 2020 Interleukin-21 (155 aa, ~18 kDa) is encoded by the human IL21 gene. This protein plays a role in both receptor-mediated signaling and the inflammatory response.
semanticscholar +1 more source
Cloning and characterization of an isoform of interleukin‐21 [PDF]
FEBS Letters, 2007 Interleukin‐21 (IL‐21) has pleiotropic functions on the cells, which play roles in both innate and acquired immunity, such as T cells, B cells, natural killer (NK) cells and dendritic cells. In this study we identified a novel isoform of IL‐21, IL‐21iso in human and mouse. IL‐21iso might be an alternative splicing variant form and the C‐terminal region
Akemi Araki +6 more
openaire +3 more sources
Addition of Interleukin-21 for Expansion of T-Cells for Adoptive Immunotherapy of Murine Melanoma [PDF]
, 2015 We previously demonstrated that interleukin (IL)-7/15 was superior to IL-2 for expansion of T cells in vitro for adoptive immunotherapy. We sought to ascertain whether IL-21 would further improve yield and therapeutic efficacy of T cells in culture ...
Bear, Harry D. +3 more
core +6 more sources