Results 91 to 100 of about 615,879 (297)

Expression of Interleukin-1 and Temporomandibular Disorder: Contemporary Review of the Literature [PDF]

, 2017
Objective: Temporomandibular disorders (TMD) are a group of conditions affecting the temporomandibular joint (TMJ), leading to jaw dysfunction, joint and muscle pain, and a decrease in quality of life.
Almeida, Luis Eduardo, Bosio, Jose A., Butcher, Seth, Hresko, Kyle, Leonardi, Rosalia, Loreto, Carla, Pierce, Sean, Sorenson, Adam, Tramontina, Vinícius Augusto   +8 more
core   +1 more source

Targeting self- and foreign antigens to dendritic cells via DC-ASGPR generates IL-10-producing suppressive CD4+ T cells [PDF]

, 2012
Dendritic cells (DCs) can initiate and shape host immune responses toward either immunity or tolerance by their effects on antigen-specific CD4(+) T cells.
Akira, Anderson, Anna Karolina Palucka, Anne O’Garra, Anne-Laure Flamar, Awasthi, Bacchetta, Banchereau, Banchereau, Barrat, Baumgart, Bergman, Brown, Caparrós, Caux, Dapeng Li, Delneste, Dillon, Dorothée Duluc, Dudziak, Feng, Figdor, Gabrielle Romain, Gabrysová, Geijtenbeek, Geijtenbeek, Gerard Zurawski, Geurtsen, Gringhuis, Gringhuis, Groux, Häringer, Ito, Jacques Banchereau, Jankovic, Kaiser, Kappos, Klechevsky, LeibundGut-Landmann, Levings, Macián, Maldonado-López, Melissa Dullaers, Moore, Nathalie Bosquet, Ni, O’Garra, Pulendran, Reddy, Rissoan, Roger Le Grand, Rogers, Roncarolo, Sagoo, Saijo, Sandra Zurawski, SangKon Oh, Saraiva, Saraiva, Schreiber, Shortman, Smits, Soares, Steinman, Trinchieri, Valladeau, Xiao-Hua Li   +66 more
core   +2 more sources

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Benralizumab for acute thromboembolism in hypereosinophilic syndrome: a case report

Allergy, Asthma & Clinical Immunology
Background Hypereosinophilic syndrome is a group of disorders characterized by organ dysfunction caused by hypereosinophilia, which frequently leads to thromboembolic complications with potentially fatal outcomes.
Daiki Nagira, Satoshi Miyamoto, Taishiro Mizukoshi, Atsushi Yanagisawa, Atsushi Funauchi, Kensuke Kanaoka, Hanako Yoshimura, Tatsunori Jo, Masayoshi Higashiguchi, Yujiro Naito, Takayuki Shiroyama, Satoshi Tetsumoto, Haruhiko Hirata, Yoshito Takeda, Atsushi Kumanogoh   +14 more
doaj   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

Evolution of Th2 responses : Characterization of IL-4/13 in sea bass (Dicentrarchus labrax L.) and studies of expression and biological activity [PDF]

, 2017
Acknowledgements This research was funded by the European Commission under the 7th Framework Programme for Research and Technological Development (FP7) of the European Union (Grant Agreement 311993 TARGETFISH). T.W.
A Antczak, A Bhattacharjee, A Munitz, AE Lockyer, E Wangkahart, EJ Song, F Buonocore, F Takizawa, G Biswas, G Scapigliati, H Nielsen, J Zhu, J Zou, JE Allen, JH Li, JW Hodgkinson, K Bao, K Tamura, L-y Zhu, LM Braden, M Howard, M Ohtani, M Tine, M Wills-Karp, MG Reese, MM Costa, MO Huising, N Nunez Ortiz, PJ Lupardus, RC Edgar, RL Coffman, S Almeria, S Kumar, S McCormick, SP Gadani, T Hage, T Maehr, T Wang, T Wang, T Wang, T Wang, T Yamaguchi, T Yamaguchi, TA Wynn, TA Wynn   +44 more
core   +1 more source

Reciprocal regulation of interleukin‑17A and interleukin‑22 secretion through aryl hydrocarbon receptor activation in CD4⁺ T cells of patients with vitiligo

Experimental and Therapeutic Medicine, 2020
Previous studies have shown the participation of the cytokines interleukin (IL) 17A and IL22 in the development of vitiligo. The aryl hydrocarbon receptor (AhR) functions in the pathogenesis of vitiligo and can modulate cytokine production. The aim of the present study was to determine the relationship between AhR activation and the secretion of IL17A ...
Liu, Baoyi, Xie, Yongyi, Mei, Xingyu, Sun, Yue, Shi, Weimin, Wu, Zhouwei   +5 more
openaire   +3 more sources

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

In Vivo Dioxin Favors Interleukin-22 Production by Human CD4+ T Cells in an Aryl Hydrocarbon Receptor (AhR)-Dependent Manner

PLoS ONE, 2011
The transcription factor aryl hydrocarbon receptor (AhR) mediates the effects of a group of chemicals known as dioxins, ubiquitously present in our environment. However, it is poorly known how the in vivo exposure to these chemicals affects in humans the adaptive immune response.
Brembilla Nicolò Costantino, Ramirez Jean-Marie, Chicheportiche Rachel, Sorg Olivier, Saurat Jean-Hilaire, Chizzolini Carlo   +5 more
openaire   +6 more sources

Synthetic interleukin 22 (IL-22) signaling reveals biological activity of homodimeric IL-10 receptor 2 and functional cross-talk with the IL-6 receptor gp130

Journal of Biological Chemistry, 2020
Cytokine signaling is transmitted by cell-surface receptors that function as biological switches controlling mainly immune-related processes. Recently, we have designed synthetic cytokine receptors (SyCyRs) consisting of GFP and mCherry nanobodies fused to transmembrane and intracellular domains of cytokine receptors that phenocopy cytokine signaling ...
Sofie Mossner, Marcus Kuchner, Nastaran Fazel Modares, Birgit Knebel, Hadi Al-Hasani, Doreen M. Floss, Jürgen Scheller   +6 more
openaire   +2 more sources