New Interleukin-23 Antagonists’ Use in Crohn’s Disease [PDF]
PharmaceuticalsCrohn’s disease (CD) is a chronic inflammatory condition of the digestive tract, driven by an imbalance in immune system regulation, where proinflammatory interleukin-23 (IL-23) plays an essential role.
Laura Biskup +5 more
doaj +4 more sources
Turkderm Turkish Archives of Dermatology and Venereology, 2022 For adult patients with moderate to severe plaque psoriasis scheduled for systemic therapy, FDA-approved agents that act via interleukin-23 (IL-23) inhibition are guselkumab, tildrakizumab, and risankizumab.
Esra Adışen
doaj +3 more sources
The presence, severity, and onset of preeclampsia is associated with maternal interleukin-23 level: A case-control study [PDF]
International Journal of Reproductive BioMedicine, 2023 Background: Scientific evidence support that imbalance between inflammatory and anti-inflammatory cytokines play a critical role in preeclampsia (PE). Objective: To investigate the relationship between the maternal serum level of interleukin (IL)-23, a ...
Forough Forghani +2 more
doaj +2 more sources
Interleukin-23 Involved in Fibrotic Autoimmune Diseases: New Discoveries. [PDF]
J Clin Med, 2023 Sisto M, Lisi S.
europepmc +5 more sources
Analysis of Interleukin-17, Interleukin-23, neopterin and Nesfatin-1 levels in the sera of Hashimoto patients [PDF]
Journal of Medical Biochemistry, 2023 Background: Hashimoto's thyroiditis (HT) is an autoimmune disorder affecting the thyroid gland and may present as goiter or atrophic thyroiditis that may result in various metabolic and inflammatory disorders.
Bayraktar Nihayet +4 more
doaj +2 more sources
Anti-Interleukin-23 Autoantibodies in Adult-Onset Immunodeficiency. [PDF]
N Engl J MedAutoantibodies against interleukin-12 (anti-interleukin-12) are often identified in patients with thymoma, but opportunistic infections develop in only some of these patients. Interleukin-12 (with subunits p40 and p35) shares a common subunit with interleukin-23 (subunits p40 and p19). In a patient with disseminated Burkholderia gladioli infection, the
Cheng A +21 more
europepmc +7 more sources
Impact of Brucellosis on Interleukin -23 Level, Acid Phosphates and Some Other Trace Elements
Journal of Pure and Applied Microbiology, 2018 The study was carried out during a period of February 2017-July 2018 for the detection of brucellosis in 128 suspected patients with age group range from 17 - 69 years, who attended to Baghdad teaching hospitals, that had been examined and defined as ...
Khalil Ismail A. Mohamed +6 more
doaj +3 more sources
Interleukin-23 in perspective. [PDF]
Rheumatology (Oxford), 2021 Sherlock JP, Cua DJ.
europepmc +4 more sources
Efficacy of interleukin-12/23 and interleukin-23 inhibitors in Hailey-Hailey disease [PDF]
JAAD Case ReportsCaroline Echeandia-Francis, BA +5 more
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Epithelial-derived interleukin-23 promotes oral mucosal immunopathology. [PDF]
ImmunityAt mucosal surfaces, epithelial cells provide a structural barrier and an immune defense system. However, dysregulated epithelial responses can contribute to disease states. Here, we demonstrated that epithelial cell-intrinsic production of interleukin-23 (IL-23) triggers an inflammatory loop in the prevalent oral disease periodontitis.
Kim TS +23 more
europepmc +3 more sources