Results 31 to 40 of about 3,836,767 (289)

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies [PDF]

open access: yes, 2012
BACKGROUND: Persistent inflammation has been proposed to contribute to various stages in the pathogenesis of cardiovascular disease. Interleukin-6 receptor (IL6R) signalling propagates downstream inflammation cascades.
Thomas, GN   +492 more
core   +1 more source

Distinct effects of endogenous interleukin-23 on eosinophilic airway inflammation in response to different antigens

open access: yesAllergology International, 2015
Background: The role of interleukin (IL)-23 in asthma pathophysiology is still controversial. We examined its role in allergic airway inflammation in response to two distinct antigens using IL-23-deficient mice.
Rika Ogawa   +9 more
doaj   +1 more source

Interleukin-17A and interleukin-23 in morphea

open access: yesArchives of Medical Science, 2012
Morphea is a disease included in the group of scleroderma type autoimmune diseases. Interleukin (IL)-17A may play a role at every stage of its pathogenesis. The study aimed at evaluation of IL-17A and IL-23 (as the main cytokine which is supposed to stimulate and maintain synthesis of IL-17) in pathogenesis of morphea.The studies were performed on 41 ...
Dańczak-Pazdrowska, Aleksandra   +9 more
openaire   +2 more sources

IL-23 Inhibition in Ankylosing Spondylitis: Where Did It Go Wrong?

open access: yesFrontiers in Immunology, 2021
Axial spondyloarthritis is a prevalent form of chronic arthritis which is related to psoriatic arthritis and skin psoriasis. TNF and IL-17A as well as IL-17F are key cytokines contributing to the pathobiology of this disease, as evidence by the ...
Dominique Baeten   +2 more
doaj   +1 more source

Interleukin-22 predicts severity and death in advanced liver cirrhosis: a prospective cohort study [PDF]

open access: yes, 2012
Background: Interleukin-22 (IL-22), recently identified as a crucial parameter of pathology in experimental liver damage, may determine survival in clinical end-stage liver disease.
Stefan Zeuzem   +23 more
core   +2 more sources

Correlation of Interleukin-17 and 23 Inflammatory Markers with Genetically Transmitted Spondyloarthritis Patients at a Tertiary Care Facility, South India [PDF]

open access: yes, 2023
Human leukocyte antigens (HLA) are genetically derived proteins in the major histocompatibility complex. They help distinguish “self” and “non-self” antigens and are essential in interacting with the immune cells inside the body.
K.V. Leela   +4 more
core   +1 more source

Expressions of IL-17, IL-21 and IL-23 in the serum of allergic rhinitis patients [PDF]

open access: yesJournal of Medical Biochemistry, 2011
The present study aimed to investigate the expressions of interleukin-17 (IL-17), IL-21 and IL-23 in the serum of allergic rhinitis (AR) patients and to explore their relationship with special IgE (sFgE) in the serum.
Huang Xuekun   +5 more
doaj  

The interleukin‐23 axis in intestinal inflammation

open access: yesImmunological Reviews, 2008
Summary: Immune responses in the intestine are tightly regulated to ensure host protective immunity in the absence of immune pathology. Interleukin‐23 (IL‐23) has recently been shown to be a key player in influencing the balance between tolerance and immunity in the intestine.
Ahern, P, Izcue, A, Maloy, K, Powrie, F
openaire   +2 more sources

Serum Levels of Il-12 and Il-23 in Breast Cancer Patients Infected with Toxoplasma gondii: A Case-Control Study

open access: yesIranian Journal of Parasitology, 2020
Background: The possible risk factor of Toxoplasma infection and its possible correlation with Interleukin-12 (IL-12) and Interleukin-23 (IL-23) in breast cancer patients was investigated. Methods: Overall, 190 female patients referred to the Oncology
Maha Mustafa ASSIM, Entsar Jabbar SAHEB
doaj   +1 more source

Association of Interleukin 23 Receptor Gene with Sarcoidosis [PDF]

open access: yesDisease Markers, 2011
Interleukin 23 receptor (IL23R) gene has been reported as a genetic factor strongly associated with inflammatory bowel disease, psoriasis, and ankylosing spondylitis. We investigated the association betweenIL23Rgene single nucleotide polymorphisms (SNPs) and susceptibility to sarcoidosis, including the clinical manifestation of uveitis.Ninety-one ...
Hyun Soo Kim   +9 more
openaire   +3 more sources

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