Impact of Brucellosis on Interleukin -23 Level, Acid Phosphates and Some Other Trace Elements
Journal of Pure and Applied Microbiology, 2018 The study was carried out during a period of February 2017-July 2018 for the detection of brucellosis in 128 suspected patients with age group range from 17 - 69 years, who attended to Baghdad teaching hospitals, that had been examined and defined as ...
Khalil Ismail A. Mohamed +6 more
doaj +2 more sources
Use of NanoBiT and NanoBRET to characterise interleukin-23 receptor dimer formation in living cells. [PDF]
Br J Pharmacol, 2023 Background and Purpose: Interleukin-23 (IL-23) and its receptor are important drug targets for the treatment of auto-inflammatory diseases. IL-23 binds to a receptor complex composed of two single transmembrane spanning proteins IL23R and IL12Rβ1.
Lay CS +3 more
europepmc +2 more sources
Significance of Interleukin 23 in Systemic Lupus Patients: Relation to Disease Activity and Damage Indices. [PDF]
Biologics, 2023 Maysa M Haroon,1 Gehan A Hegazy,2,3 Mohammed A Hassanien,4,5 Olfat Shaker,6 Wafaa H Hussein1 1Department of Rheumatology, Faculty of Medicine, Cairo University, Cairo, Egypt; 2Clinical Biochemistry Department, Faculty of Medicine, King Abdulaziz ...
Haroon MM +4 more
europepmc +2 more sources
Current concepts in the pathogenesis of spondyloarthritis
Indian Journal of Rheumatology, 2020 Pathogenesis of spondyloarthritis (SpA) is multifactorial and still not understood entirely. The role of genetics including human leukocyte antigen B27 has been investigated extensively, which along with genome-wide association studies has helped us ...
Nibha Jain, Arumugam Moorthy
doaj +1 more source
Interleukin 23 in the skin: role in psoriasis pathogenesis and selective interleukin 23 blockade as treatment [PDF]
Therapeutic Advances in Chronic Disease, 2018 Plaque psoriasis is one of the most common autoimmune skin diseases and is characterized by erythematous, scaly plaques. Many highly effective, targeted therapies have been developed as a result of an improved understanding of the pathogenesis of psoriasis.
Tom C, Chan +2 more
openaire +2 more sources
Microglia-Derived Interleukin 23: A Crucial Cytokine in Alzheimer's Disease?
Frontiers in Neurology, 2021 Neuronal cell death, amyloid β plaque formation and development of neurofibrillary tangles are among the characteristics of Alzheimer's disease (AD). In addition to neurodegeneration, inflammatory processes such as activation of microglia and astrocytes ...
Louisa Nitsch +3 more
doaj +1 more source
Analysis of Interleukin-17, Interleukin-23, neopterin and Nesfatin-1 levels in the sera of Hashimoto patients [PDF]
Journal of Medical Biochemistry, 2023 Background: Hashimoto's thyroiditis (HT) is an autoimmune disorder affecting the thyroid gland and may present as goiter or atrophic thyroiditis that may result in various metabolic and inflammatory disorders.
Bayraktar Nihayet +4 more
doaj +1 more source
Journal of Investigative Surgery, 2021 Background Idiopathic Granulomatous Mastitis (IGM) is a benign chronic inflammatory breast disease that mimics breast cancer, and the etiopathogenesis has not yet been fully evaluated. Autoimmunity has received the most focus as a possible etiology.
Mehmet Saydam +8 more
doaj +1 more source
Regulation of Interleukin-23 Receptor expression in human T-Lymphocytes [PDF]
, 2022 openChronic inflammatory diseases (CID) are clinically heterogeneous conditions that share common inflammatory pathways and derive from aberrant immune responses.
CREMA, ALESSIA
core
Risk of Cutaneous T Cell Lymphoma with Psoriasis Biologic Therapies
Dermatology and Therapy, 2023 Background The risk of developing cutaneous T cell lymphoma (CTCL) in patients using psoriasis biologics has not been well characterized. The goals of this review were to investigate the incidence of CTCL in patients with psoriasis receiving biologic ...
Mitchell S. Davis +7 more
doaj +1 more source