Results 11 to 20 of about 535,272 (261)
Current concepts in the pathogenesis of spondyloarthritis
Indian Journal of Rheumatology, 2020 Pathogenesis of spondyloarthritis (SpA) is multifactorial and still not understood entirely. The role of genetics including human leukocyte antigen B27 has been investigated extensively, which along with genome-wide association studies has helped us ...
Nibha Jain, Arumugam Moorthy
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Microglia-Derived Interleukin 23: A Crucial Cytokine in Alzheimer's Disease?
Frontiers in Neurology, 2021 Neuronal cell death, amyloid β plaque formation and development of neurofibrillary tangles are among the characteristics of Alzheimer's disease (AD). In addition to neurodegeneration, inflammatory processes such as activation of microglia and astrocytes ...
Louisa Nitsch +3 more
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Analysis of Interleukin-17, Interleukin-23, neopterin and Nesfatin-1 levels in the sera of Hashimoto patients [PDF]
Journal of Medical Biochemistry, 2023 Background: Hashimoto's thyroiditis (HT) is an autoimmune disorder affecting the thyroid gland and may present as goiter or atrophic thyroiditis that may result in various metabolic and inflammatory disorders.
Bayraktar Nihayet +4 more
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Interleukin 23 in the skin: role in psoriasis pathogenesis and selective interleukin 23 blockade as treatment [PDF]
Therapeutic Advances in Chronic Disease, 2018 Plaque psoriasis is one of the most common autoimmune skin diseases and is characterized by erythematous, scaly plaques. Many highly effective, targeted therapies have been developed as a result of an improved understanding of the pathogenesis of psoriasis.
Tom C, Chan +2 more
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Journal of Investigative Surgery, 2021 Background Idiopathic Granulomatous Mastitis (IGM) is a benign chronic inflammatory breast disease that mimics breast cancer, and the etiopathogenesis has not yet been fully evaluated. Autoimmunity has received the most focus as a possible etiology.
Mehmet Saydam +8 more
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Risk of Cutaneous T Cell Lymphoma with Psoriasis Biologic Therapies
Dermatology and Therapy, 2023 Background The risk of developing cutaneous T cell lymphoma (CTCL) in patients using psoriasis biologics has not been well characterized. The goals of this review were to investigate the incidence of CTCL in patients with psoriasis receiving biologic ...
Mitchell S. Davis +7 more
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The Role of Interleukin-17 in Juvenile Idiopathic Arthritis: From Pathogenesis to Treatment
Medicina, 2022 Background and Objectives: Interleukin-17 (IL-17) is a cytokine family consisting of six members and five specific receptors. IL-17A was the first member to be identified in 1993.
Marino Paroli +5 more
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Interleukin 23 Levels Are Increased in Carotid Atherosclerosis [PDF]
Stroke, 2015 Background and Purpose— Interleukin (IL)-23 is a cytokine in the IL-12 family, mainly produced by antigen-presenting cells with a central role in inflammation. We hypothesize that IL-23 is also important in atherogenesis and investigate this in a population with carotid atherosclerosis. Methods—
Abbas, Azhar +18 more
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Acta Medica Bulgarica, 2022 In this manuscript we are discussing our research of the presence of single nucleotide polymorphisms (SNPs) of two proinflammatory cytokines – interleukin 17F (IF-17F) and interleukin 23 (IL-23) in a cohort of Bulgarian patients.
Pashova-Tasseva Z. +3 more
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Interleukin-23: A central cytokine in the pathogenesis of spondylarthritis [PDF]
Arthritis & Rheumatism, 2011 One of the most satisfying aspects of the genome-wide association studies conducted in patients withankylosing spondylitis (AS) has been the large numberof genes that have been shown to affect susceptibility todisease (1). The first gene of this kind to be identifiedwas the interleukin-23 receptor (IL-23R).
Gaston, J. S. Hill +2 more
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