Results 21 to 30 of about 60,158,519 (252)

Current concepts in the pathogenesis of spondyloarthritis

open access: yesIndian Journal of Rheumatology, 2020
Pathogenesis of spondyloarthritis (SpA) is multifactorial and still not understood entirely. The role of genetics including human leukocyte antigen B27 has been investigated extensively, which along with genome-wide association studies has helped us ...
Nibha Jain, Arumugam Moorthy
doaj   +1 more source

Microglia-Derived Interleukin 23: A Crucial Cytokine in Alzheimer's Disease?

open access: yesFrontiers in Neurology, 2021
Neuronal cell death, amyloid β plaque formation and development of neurofibrillary tangles are among the characteristics of Alzheimer's disease (AD). In addition to neurodegeneration, inflammatory processes such as activation of microglia and astrocytes ...
Louisa Nitsch   +3 more
doaj   +1 more source

Analysis of Interleukin-17, Interleukin-23, neopterin and Nesfatin-1 levels in the sera of Hashimoto patients [PDF]

open access: yesJournal of Medical Biochemistry, 2023
Background: Hashimoto's thyroiditis (HT) is an autoimmune disorder affecting the thyroid gland and may present as goiter or atrophic thyroiditis that may result in various metabolic and inflammatory disorders.
Bayraktar Nihayet   +4 more
doaj   +1 more source

New Findings on Autoimmune Etiology of Idiopathic Granulomatous Mastitis: Serum IL-17, IL-22 and IL-23 Levels of Patients

open access: yesJournal of Investigative Surgery, 2021
Background Idiopathic Granulomatous Mastitis (IGM) is a benign chronic inflammatory breast disease that mimics breast cancer, and the etiopathogenesis has not yet been fully evaluated. Autoimmunity has received the most focus as a possible etiology.
Mehmet Saydam   +8 more
doaj   +1 more source

Risk of Cutaneous T Cell Lymphoma with Psoriasis Biologic Therapies

open access: yesDermatology and Therapy, 2023
Background The risk of developing cutaneous T cell lymphoma (CTCL) in patients using psoriasis biologics has not been well characterized. The goals of this review were to investigate the incidence of CTCL in patients with psoriasis receiving biologic ...
Mitchell S. Davis   +7 more
doaj   +1 more source

Regulation of Interleukin-23 Receptor expression in human T-Lymphocytes [PDF]

open access: yes, 2022
openChronic inflammatory diseases (CID) are clinically heterogeneous conditions that share common inflammatory pathways and derive from aberrant immune responses.
CREMA, ALESSIA
core  

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies [PDF]

open access: yes, 2012
BACKGROUND: Persistent inflammation has been proposed to contribute to various stages in the pathogenesis of cardiovascular disease. Interleukin-6 receptor (IL6R) signalling propagates downstream inflammation cascades.
Thomas, GN   +489 more
core   +1 more source

The Role of Interleukin-17 in Juvenile Idiopathic Arthritis: From Pathogenesis to Treatment

open access: yesMedicina, 2022
Background and Objectives: Interleukin-17 (IL-17) is a cytokine family consisting of six members and five specific receptors. IL-17A was the first member to be identified in 1993.
Marino Paroli   +5 more
doaj   +1 more source

Early production of IL-22 but not IL-17 by peripheral blood mononuclear cells exposed to live Borrelia burgdorferi: the role of monocytes and interleukin-1 [PDF]

open access: yes, 2010
If insufficiently treated, Lyme borreliosis can evolve into an inflammatory disorder affecting skin, joints, and the CNS. Early innate immunity may determine host responses targeting infection. Thus, we sought to characterize the immediate cytokine storm
Nicole Darsow   +38 more
core   +1 more source

Interleukin-22 predicts severity and death in advanced liver cirrhosis: a prospective cohort study [PDF]

open access: yes, 2012
Background: Interleukin-22 (IL-22), recently identified as a crucial parameter of pathology in experimental liver damage, may determine survival in clinical end-stage liver disease.
Stefan Zeuzem   +35 more
core   +2 more sources

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