Results 21 to 30 of about 3,836,767 (289)

New Findings on Autoimmune Etiology of Idiopathic Granulomatous Mastitis: Serum IL-17, IL-22 and IL-23 Levels of Patients

Journal of Investigative Surgery, 2021
Background Idiopathic Granulomatous Mastitis (IGM) is a benign chronic inflammatory breast disease that mimics breast cancer, and the etiopathogenesis has not yet been fully evaluated. Autoimmunity has received the most focus as a possible etiology.
Mehmet Saydam, Kerim Bora Yilmaz, Mutlu Sahin, Hamdullah Yanik, Melih Akinci, Ibrahim Yilmaz, Sener Balas, Cem Azili, Mehmet Ali Gulcelik   +8 more
doaj   +1 more source

Risk of Cutaneous T Cell Lymphoma with Psoriasis Biologic Therapies

Dermatology and Therapy, 2023
Background The risk of developing cutaneous T cell lymphoma (CTCL) in patients using psoriasis biologics has not been well characterized. The goals of this review were to investigate the incidence of CTCL in patients with psoriasis receiving biologic ...
Mitchell S. Davis, Riley K. Spencer, Chandler E. Johnson, Kareem G. Elhage, Joy Q. Jin, Marwa Hakimi, Tina Bhutani, Wilson Liao   +7 more
doaj   +1 more source

The Role of Interleukin-17 in Juvenile Idiopathic Arthritis: From Pathogenesis to Treatment

Medicina, 2022
Background and Objectives: Interleukin-17 (IL-17) is a cytokine family consisting of six members and five specific receptors. IL-17A was the first member to be identified in 1993.
Marino Paroli, Luca Spadea, Rosalba Caccavale, Leopoldo Spadea, Maria Pia Paroli, Nicola Nante   +5 more
doaj   +1 more source

Interleukin 23 Levels Are Increased in Carotid Atherosclerosis [PDF]

Stroke, 2015
Background and Purpose— Interleukin (IL)-23 is a cytokine in the IL-12 family, mainly produced by antigen-presenting cells with a central role in inflammation. We hypothesize that IL-23 is also important in atherogenesis and investigate this in a population with carotid atherosclerosis. Methods—
Abbas, Azhar, Gregersen, Ida, Holm, Sverre, Daissormont, Isabelle, Bjerkeli, Vigdis, Krohg-Sorensen, Kirsten, Skagen, Karolina R., Dahl, Tuva B., Russell, David, Almas, Trine, Bundgaard, Dorte, Alteheld, Lars Holger, Rashidi, Azita, Dahl, Christen P., Michelsen, Annika E., Biessen, Erik A., Aukrust, Pal, Halvorsen, Bente, Skjelland, Mona   +18 more
openaire   +3 more sources

Trypanosomiasis-induced Th17-like immune responses in carp [PDF]

, 2010
Background - In mammalian vertebrates, the cytokine interleukin (IL)-12 consists of a heterodimer between p35 and p40 subunits whereas interleukin-23 is formed by a heterodimer between p19 and p40 subunits.
B M Lidy Verburg-van Kemenade, Verburg-van Kemenade, B.M.L., Chadzinska Magdalena, Wiegertjes Geert F., Chadzinska, M.K., Huub F. J. Savelkoul, Scheer Marleen, Savelkoul, H.F.J., Scheer, M.H., Geert F Wiegertjes, Savelkoul Huub F. J., Bird, S., Maria J. S. L. Pontes, Ribeiro, Carla M. S., B. M. Lidy Verburg-van Kemenade, Wiegertjes, G.F., Savelkoul, Huub F. J., Carla M S Ribeiro, Scheer, Marleen, Marleen Scheer, Verburg-van Kemenade B. M. Lidy, Steve Bird, Maria J S L Pontes, Huub F J Savelkoul, Pontes, Maria J. S. L., Verburg-van Kemenade, B. M. Lidy, Ribeiro, C.M.S., Wiegertjes, Geert F., Bird Steve, Magdalena Chadzinska, Carla M. S. Ribeiro, Pontes, M.J.S.L., Ribeiro Carla M. S., Chadzinska, Magdalena, Pontes Maria J. S. L., Bird, Steve, Geert F. Wiegertjes   +36 more
core   +2 more sources

Interleukin-23: A central cytokine in the pathogenesis of spondylarthritis [PDF]

Arthritis & Rheumatism, 2011
One of the most satisfying aspects of the genome-wide association studies conducted in patients withankylosing spondylitis (AS) has been the large numberof genes that have been shown to affect susceptibility todisease (1). The first gene of this kind to be identifiedwas the interleukin-23 receptor (IL-23R).
Gaston, J. S. Hill, Goodall, Jane C., Baeten, Dominique   +2 more
openaire   +2 more sources

The IL23R R381Q gene variant protects against immune-mediated diseases by impairing IL-23-induced Th17 effector response in humans [PDF]

, 2011
IL-23 and Th17 cells are key players in tissue immunosurveillance and are implicated in human immune-mediated diseases. Genome-wide association studies have shown that the IL23R R381Q gene variant protects against psoriasis, Crohn's disease and ...
Di Meglio, P, Chung-Ching Chu, Francesca Capon, Di Meglio, Paola, Napolitano, Luca, Napolitano, L, Ketty Peris, Di Cesare, Antonella, Villanova, Federica, Villanova, F, Richard C. Trembath, Isabella Tosi, Paola Di Meglio, Richard C Trembath, Laggner, Ute, Chu, Chung-Ching, Chu, CC, Capon, Francesca, Federica Villanova, Frank O Nestle, Nestle, FO, Peris, K, Nestle, Frank O., Antonella Di Cesare, Peris, Ketty, Trembath, RC, Laggner, U, Tosi, Isabella, Luca Napolitano, Capon, F, Frank O. Nestle, Ute Laggner, Trembath, Richard C., Di Cesare, A, Tosi, I   +34 more
core   +2 more sources

Early production of IL-22 but not IL-17 by peripheral blood mononuclear cells exposed to live Borrelia burgdorferi: the role of monocytes and interleukin-1 [PDF]

, 2010
If insufficiently treated, Lyme borreliosis can evolve into an inflammatory disorder affecting skin, joints, and the CNS. Early innate immunity may determine host responses targeting infection. Thus, we sought to characterize the immediate cytokine storm
Nicole Darsow, Kind, Peter, Rudloff, Ina, Klaus-Peter Hunfeld, Katharina Horn, Itamar Goren, Urs Christen, Kraiczy Peter, Horn Katharina, Pfeilschifter, Josef (Prof. Dr.), Mühl Heiko, Koehl Ulrike, Peter Kind, Goren Itamar, Pfeilschifter, Josef, Peter Kraiczy, Rudloff Ina, Goren, Itamar, Mühl, Heiko, Darsow, Nicole, Christen Urs, Kraiczy, Peter, Christen, Urs, Holdener, Martin, Horn, Katharina, Hunfeld, Klaus-Peter, Ulrike Koehl, Hunfeld Klaus-Peter, Heiko Mühl, Ina Rudloff, Malte Bachmann, Martin Holdener, Holdener Martin, Koehl, Ulricke, Bachmann Malte, Darsow Nicole, Kind Peter, Köhl, Ulrike, Josef Pfeilschifter, Bachmann, Malte, Pfeilschifter Josef   +40 more
core   +1 more source

Interleukin-18 [PDF]

, 2003
Interleukin-18 (IL-18), a recently described member of the IL-1 cytokine superfamily, is now recognized as an important regulator of innate and acquired immune responses.
McInnes, I.B., Robertson, S.E., Gracie, J.A.   +2 more
core   +1 more source

Proinflammatory Cytokine Polymorphisms and Severity of Periodontitis in a Cohort of Bulgarian Patients

Acta Medica Bulgarica, 2022
In this manuscript we are discussing our research of the presence of single nucleotide polymorphisms (SNPs) of two proinflammatory cytokines – interleukin 17F (IF-17F) and interleukin 23 (IL-23) in a cohort of Bulgarian patients.
Pashova-Tasseva Z., Popova Ch., Tosheva E., Mlachkova A.   +3 more
doaj   +1 more source