Results 101 to 110 of about 530,938 (302)
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat +11 more
wiley +1 more source
Correction to: Critical role of interleukin-23 in development of asthma promoted by cigarette smoke [PDF]
Hyun Seung Lee +6 more
openalex +1 more source
Tildrakizumab in the treatment of psoriasis: latest evidence and place in therapy. [PDF]
Psoriasis is a chronic inflammatory disorder that is clinically characterized by scaly cutaneous plaques. New evidence suggests that dysregulation of interleukin (IL)-23, a key cytokine in the T-helper-17 pathway, plays a vital role in the development of
Lee, Erica B +4 more
core
A hydrogel with dynamic cross‐links was formed by cross‐linking hyaluronic acid with curcumin‐preloaded, phenylboronic acid‐modified poly(amidoamine) dendrimers. This hydrogel exhibited excellent injectability and self‐healing ability, enabling controlled Cur release in response to low pH, high reactive oxygen species (ROS) generation, or mechanical ...
Junjie Liu +9 more
wiley +1 more source
Key inflammatory pathway activations in the MCI stage of Alzheimer's disease [PDF]
OBJECTIVE: To determine the key inflammatory pathways that are activated in the peripheral and CNS compartments at the mild cognitive impairment (MCI) stage of Alzheimer's disease (AD).
Bekris, Lynn M. +7 more
core +2 more sources
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim +5 more
wiley +1 more source
Interleukin‐23: as a drug target for autoimmune inflammatory diseases [PDF]
Chunlei Tang +3 more
openalex +1 more source
Microfluidic Modeling of Macrophage‐Induced Cardiac Inflammation Using NF‐κB Reporter Cardiomyocytes
A cardiac inflammation model was developed to enable real‐time analysis of macrophage‐cardiomyocyte interactions using NF‐κB‐reporter cardiomyocytes and a microfluidic co‐culture system. A MATLAB‐based model was implemented to optimize cell density and medium resupply based on TNFα diffusion kinetics. Activation thresholds and stress responses in NF‐κB‐
Chao Liu +6 more
wiley +1 more source
Th17 and Interleukin 23 in the Pathogenesis of Psoriatic Arthritis and Spondyloarthritis [PDF]
Alberto Cauli, Alessandro Mathieu
openalex +1 more source
INTERLEUKIN - 23, PROSPECTS OF APPLICATION (LITERATURE REVIEW)
With the advent of new technologies, several new pro-inflammatory cytokines have been characterized, such as IL-23, which plays an important role in the pathogenesis of a number of inflammatory diseases. IL-23 pathways, as well as other proteins involved in the pathogenesis of inflammatory diseases, are currently under development and show promising ...
openaire +1 more source

