Results 71 to 80 of about 2,200,720 (269)

Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease [PDF]

open access: yes, 2009
Traditionally, Crohn's disease has been associated with a Th1 cytokine profile, while Th2 cytokines are modulators of ulcerative colitis. This concept has been challenged by the description of tolerising regulatory T cells (Treg) and by proinflammatory ...
Brand, Stephan
core   +1 more source

Miscellanea. Levelek a szerkesztőhöz. Folyóirat-referátumok. Könyvismertetés [PDF]

open access: yes, 2015
Levelek a szerkesztőhöz. Hozzászólás Kovács E., Pikó B.: A vallásfüggőség mint egy lehetséges új viselkedési addikció vizsgálata serdülőkorú populációban című cikkéhez | Válasz dr.
Kovács, Eszter   +2 more
core   +1 more source

Interleukin-31: A New Cytokine Involved in Inflammation of the Skin [PDF]

open access: yesInternational Journal of Immunopathology and Pharmacology, 2006
Department of Medicine and Science of Aging, University of Chieti, Chieti, Italy; Department of Parasitology, Veterinary School, Aristotelian University, Thessaloniki, Greece; Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, Boston, U.S.A.; Division of Immunology, Infectious Diseases Otolaryngology Division,
CASTELLANI, Maria Luisa   +9 more
openaire   +5 more sources

Chronic Prurigo of Nodular Type: A Review

open access: yesActa Dermato-Venereologica, 2017
Prurigo nodularis (PN) is a subtype of chronic prurigo presenting single to multiple symmetrically distributed, hyperkeratotic and intensively itching papules and nodules.
Claudia Zeidler   +5 more
doaj   +1 more source

Deregulation of the endometrial stromal cell secretome precedes embryo implantation failure [PDF]

open access: yes, 2017
STUDY QUESTION Is implantation failure following ART associated with a perturbed decidual response in endometrial stromal cells (EnSCs)? SUMMARY ANSWER Dynamic changes in the secretome of decidualizing EnSCs underpin the transition of a hostile ...
Aberkane, Asma   +11 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Helicobacter pylori eradication: influence of interleukin-1beta –31 C/T polymorphism

open access: yesBrazilian Journal of Infectious Diseases, 2018
Aim: To analyze the influence of the –31 C/T polymorphism of the interleukin-1β gene on Helicobacter pylori eradication therapy success in patients with functional dyspepsia. Methods: Functional dyspepsia was diagnosed according to the Rome III criteria.
Tássia Flores Rech   +9 more
doaj   +3 more sources

Miscellanea. Folyóirat-referátumok. Könyvismertetés [PDF]

open access: yes, 2015
Folyóirat-referátumok. Diabetológia A 2-es típusú diabetes kezelésének személyre szóló farmakogenetikai szempontjai (Personalized medicine and type-2 diabetes: pharmakogenetic aspects of drug therapy) Barthel, A., Schwarz, P., Schindler, C.
Fischer, Tamás   +5 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Nemolizumab for chronic pruritus beyond atopic dermatitis and prurigo nodularis: a systematic review and synthesis of emerging evidence

open access: yesJournal of Dermatological Treatment
Background Nemolizumab, an anti-IL-31 receptor A antibody, is licensed for atopic dermatitis and prurigo nodularis; its role in other chronic pruritus (CP) syndromes is uncertain.Objective To synthesize efficacy, safety and strength of evidence for ...
Mohammed Shanshal, Aarthy Uthayakumar
doaj   +1 more source

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