Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease. [PDF]
Cytokine, 2020 Interleukin (IL)-38 belongs to the IL-1 family and is part of the IL-36 subfamily due to its binding to the IL-36 Receptor (IL-1R6). In the current study, we assessed the anti-inflammatory properties of IL-38 in murine models of arthritis and systemic inflammation.
Dennis M. de Graaf +12 more
semanticscholar +7 more sources
Retraction: Reduced interleukin-38 in non-small cell lung cancer is associated with tumour progression [PDF]
Open Biology, 2020 Rui Wang +3 more
doaj +3 more sources
Interleukin-38 in colorectal cancer: a potential role in precision medicine [PDF]
Cancer Immunology, Immunotherapy, 2019 Colorectal cancer (CRC) is a leading cause of cancer-related death, partly due to a lack of reliable biomarkers for early diagnosis. To improve the outcome of CRC, it is critical to provide diagnosis at an early stage using promising sensitive/specific marker(s).
Feier Chen +5 more
semanticscholar +4 more sources
Interleukin-38 in Health and Disease. [PDF]
Cytokine, 2022 Contains fulltext : 252005.pdf (Publisher’s version ) (Open Access)
Dennis M. de Graaf +3 more
semanticscholar +4 more sources
Journal of the Egyptian Women’s Dermatologic Society, 2023 Background In psoriasis, interleukin (IL)-36 is considered a pathogenic driver, whereas IL-38 was downregulated. Little is known about their role in metabolic syndrome (Ms) in psoriasis.
Marwa Ahmed Amer +6 more
openalex +3 more sources
IL-38 as a Novel Biomarker in Multiple Myeloma Patients: A Prospective Clinical Evaluation [PDF]
Cancer Management and ResearchHailan Shen, Ping Zhao, Ju Cao Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of ChinaCorrespondence: Ju Cao, Department of Laboratory Medicine, The First Affiliated Hospital
Shen H, Zhao P, Cao J
doaj +4 more sources
Interleukin 38 serum level is increased in patients with vitiligo, correlated with disease severity, and associated with signs of disease activity [PDF]
Journal of Cosmetic Dermatology, 2021 Vitiligo is an acquired cutaneous depigmenting disease caused by a T helper (Th) 1–cytotoxic T cells driven autoimmune attack against melanocytes, in which Th17 is also involved.
Radwa El‐Sayed Mahmoud Marie +3 more
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Evaluating the Role of Interleukin-36 and Interleukin-38 in Acne Vulgaris Patients [PDF]
Benha Journal of Applied Sciences, 2020 Interleukin (IL)- 36 and (IL)- 38 cytokines are individuals from the IL-1 family, which incorporate favorable to infammatory factors and over late years, much has been educated on their significant capacities in the guideline of safe reaction and, particularly, on their function in numerous infammatory skin sicknesses.
Fatma Mohamed Elesawy +3 more
openalex +2 more sources
Interleukin 38 Protects Against Lethal Sepsis [PDF]
The Journal of Infectious Diseases, 2018 Interleukin 38 (IL-38) is the most recently characterized cytokine of the interleukin 1 family. However, its role in sepsis remains unknown.Circulating IL-38 levels were measured in 2 cohorts of adult and pediatric patients with sepsis. Using 2 murine models of lipopolysaccharide (LPS)-induced endotoxemia and cecal ligation and puncture (CLP)-induced ...
Fang Xu +6 more
semanticscholar +4 more sources
Interleukin-38 promoter variants and risk of COVID-19 among Iraqis [PDF]
Immunobiology, 2022 Coronavirus disease-19 (COVID-19) has recently emerged as a respiratory infection with a significant impact on health and society. The pathogenesis is primarily attributed to a dysregulation of cytokines, especially those with pro-inflammatory and anti-inflammatory effects. Interleukin-38 (IL-38) is a recently identified anti-inflammatory cytokine with
Al-Karaawi, Ibtihal A. +3 more
openaire +3 more sources