Immunobiological Properties and Clinical Applications of Interleukin-38 for Immune-Mediated Disorders: A Systematic Review Study [PDF]
Int J Mol Sci, 2021 Exponential growth in the usage of “cytokines” (as seroimmunobiomarkers) has facilitated more accurate prognosis, early diagnosis, novel, and efficient immunotherapeutics.
A. Esmaeilzadeh +4 more
semanticscholar +2 more sources
Association of interleukin-36α and interleukin-38 with type 2 diabetes mellitus and diabetic neuropathy [PDF]
The Egyptian Journal of Internal MedicineBackground Interleukin (IL)-36α and IL-38, two novel cytokines of the IL-1 family, have recently been proposed to have a pathophysiological significance in type 2 diabetes mellitus (T2DM).
Shahad W. Nassurat +2 more
openalex +2 more sources
Low heterozygosity for rs3811050, a 5 prime untranslated region variant of the gene encoding interleukin-38 (IL1F10), is associated with a reduced risk of systemic lupus erythematosus [PDF]
Egyptian Journal of Medical Human GeneticsBackground Interleukin-38 (IL-38), an inflammatory cytokine discovered in recent years, has been implicated in the pathogenesis of systemic lupus erythematosus (SLE). IL-38 is encoded by the IL1F10 (interleukin 1 family member 10) gene.
Rawan A. Nijeeb +2 more
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Interleukin 38 reduces antigen-presentation capacity and antibody production after vaccination [PDF]
VaccineThe mechanisms that underpin low vaccine responses, which can lead to inadequate protection against infection, are still partially unclear. Interleukin (IL)-38 is a member of the IL-1 family, expressed by B cells among others, that regulates inflammatory responses.
Lisa U. Teufel +10 more
openalex +4 more sources
Reduced concentrations of the B cell cytokine interleukin 38 are associated with cardiovascular disease risk in overweight subjects [PDF]
Eur J Immunol, 2019 The IL‐1 family member IL‐38 (IL1F10) suppresses inflammatory and autoimmune conditions. Here, we report that plasma concentrations of IL‐38 in 288 healthy Europeans correlate positively with circulating memory B cells and plasmablasts.
Dennis M. de Graaf +17 more
semanticscholar +2 more sources
Al-Mustansiriyah Journal of ScienceBackground: Rheumatoid arthritis (RA), is a disease that happened because autoimmune and inflammatory effects, it is mean that the human immune system offence healthy cells in the body mistakenly, resulting in inflammation (swelling) in the impacted ...
Montadher Ali Mahdi +2 more
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IL-38 Ameliorates Skin Inflammation and Limits IL-17 Production from γδ T Cells [PDF]
Cell Reports, 2019 Summary: Interleukin-38 (IL-38) is a cytokine of the IL-1 family with a role in chronic inflammation. However, its main cellular targets and receptors remain obscure. IL-38 is highly expressed in the skin and downregulated in psoriasis patients.
Yingying Han +19 more
doaj +3 more sources
Anti-inflammatory Mechanisms of IL-38 in Chinese Patients with Allergic Rhinitis [PDF]
Iranian Journal of Immunology, 2023 Background: T-helper 17 (Th17) cell response is engaged in the onset of allergic rhinitis (AR). Moreover, interleukin (IL)-38 is thought to be involved in inhibiting cytokine secretion in the Th17 pathway.Objective: To evaluate the regulatory function of
Xiaoqiang Wang +3 more
doaj +1 more source
Interleukin-38 promotes tumor growth through regulation of CD8+ tumor-infiltrating lymphocytes in lung cancer tumor microenvironment [PDF]
Cancer Immunol Immunother, 2020 F. Kinoshita +15 more
semanticscholar +2 more sources
Pifu-xingbing zhenliaoxue zazhi, 2023 Objective To investigate the roles of cytokines, IL-36γ and IL-38, in the inflammatory response in psoriasis vulgaris. Methods Both serum and peripheral blood mononuclear cells (PBMC) were collected from 29 patients with psoriasis vulgaris (PV) and 19 ...
Jiao ZHANG +4 more
doaj +1 more source