Results 1 to 10 of about 12,582,645 (332)

Targeting interleukin 4 and interleukin 13: a novel therapeutic approach in bullous pemphigoid [PDF]

Annals of Medicine, 2023
Aim: Bullous pemphigoid (BP) is an organ-specific autoimmune bullous disease characterized by autoantibodies that target the cellular adhesion molecules BP180 and BP230.
Fangyuan Chen, Yiman Wang, Xinyi Chen, Nan Yang, Li Li   +4 more
doaj   +2 more sources

Carbonic anhydrase 8 regulates basophil activation and interleukin 4 production [PDF]

Frontiers in Immunology
Carbonic anhydrase (Car) enzymes are a family of metalloenzymes that are traditionally known for their ability to regulate pH and CO2 homeostasis. However, emerging studies now demonstrate that Car family members exhibit lineage-specific expression ...
Jianya Peng, Jianya Peng, Jianya Peng, Chandler B. Sy, Chandler B. Sy, Siyuan Zhao, Arman Sawhney, Arman Sawhney, Vanessa Espinosa, Vanessa Espinosa, Marissa N. Schroeter, Marissa N. Schroeter, Marissa N. Schroeter, John J. Ponessa, John J. Ponessa, John J. Ponessa, Krupa Chavan, Krupa Chavan, Alexander D. Lemenze, Amariliz Rivera, Amariliz Rivera, Tibor Rohacs, Mark C. Siracusa, Mark C. Siracusa   +23 more
doaj   +2 more sources

History of interleukin-4 [PDF]

Cytokine, 2015
The history of the discovery and the development of our knowledge of IL-4 exemplifies the path of progress in biomedical science. There are unanticipated twists and turns although progress is made, sometimes quickly, other times far too slowly. Illustrative is the extended time from the first report of IL-4 in 1982 to the establishment of the efficacy ...
W. Paul
openaire   +3 more sources

Interleukin 4 Measurement [PDF]

Definitions, 2020
of the amount of interleukin 4 present in a sample.
openaire   +2 more sources

Interleukin-4 and its receptor alpha in paediatric uncomplicated malaria patients from a Ghanaian case-control study [PDF]

BMC Research Notes
Objectives This study investigated gene polymorphisms in the interleukin-4 (IL-4) and its receptor alpha (IL-4Rα) gene regions in human hosts with uncomplicated malaria.
Patrick Diaba-Nuhoho
doaj   +2 more sources

The role of interleukin-4 and interleukin-5 Th2 cytokines in assessing severity and prognosis of acute pancreatitis [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2021
Introduction/Objective. Acute pancreatitis (AP) is a relatively common disease which in most patients has favorable course. However, in approximately 20% patients, the course of the disease is more severe with high mortality (40–50%).
Doklestić Krstina, Ivančević Nenad, Lončar Zlatibor, Micić Dušan, Ristić Miloš, Jovanović Bojan, Gregorić Pavle   +6 more
doaj   +1 more source

Measuring the level of IL-4 and IL-25 in the serum of eczema patients [PDF]

Romanian Journal of Infectious Diseases, 2023
Eczema is an inflammatory skin disease and may be the result of environmental factors, genetic factors, and immune factors. Itching, persistent scratching, skin redness, and dryness are the primary signs of the illness.
Ali Mohammed Abd AL-Ameer, Asmaa Adnan Najm   +1 more
doaj   +1 more source

Functional Haplotypes in Interleukin 4 Gene Associated with Periodontitis. [PDF]

PLoS ONE, 2017
Chronic periodontitis (CP) is an infectious inflammatory disease that affects tooth-supporting structures and in which dental plaque bacteria, immune mechanisms and genetic predisposition play important roles.
Giovana Anovazzi, Marcell Costa de Medeiros, Suzane Cristina Pigossi, Livia Sertori Finoti, Marcia Pinto Alves Mayer, Carlos Rossa, Raquel Mantuaneli Scarel-Caminaga   +6 more
doaj   +1 more source

Association of interleukin 4 (-590 T/C) and interleukin 4 receptor (Q551R A/G) gene polymorphisms with acne vulgaris

Annals of Saudi Medicine, 2012
BACKGROUND AND OBJECTIVES: Acne vulgaris is a common skin disorder. The complete etiology of this disease remains to be identified; however, it seems that aberrant expression of cytokine genes might be a contributing factor.
Ahmad A. Al Robaee, Abdullateef AlZolibani, Hani Al Shobaili, Ahmad Settin   +3 more
doaj   +1 more source

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha

Journal of Experimental Medicine, 1994
Using granulocyte/macrophage colony-stimulating factor (GM-CSF) and interleukin 4 we have established dendritic cell (DC) lines from blood mononuclear cells that maintain the antigen capturing and processing capacity characteristic of immature dendritic ...
F. Sallusto, A. Lanzavecchia
semanticscholar   +1 more source