Results 11 to 20 of about 14,230,992 (393)

Carbonic anhydrase 8 regulates basophil activation and interleukin 4 production [PDF]

Frontiers in Immunology
Carbonic anhydrase (Car) enzymes are a family of metalloenzymes that are traditionally known for their ability to regulate pH and CO2 homeostasis. However, emerging studies now demonstrate that Car family members exhibit lineage-specific expression ...
Jianya Peng, Jianya Peng, Jianya Peng, Chandler B. Sy, Chandler B. Sy, Siyuan Zhao, Arman Sawhney, Arman Sawhney, Vanessa Espinosa, Vanessa Espinosa, Marissa N. Schroeter, Marissa N. Schroeter, Marissa N. Schroeter, John J. Ponessa, John J. Ponessa, John J. Ponessa, Krupa Chavan, Krupa Chavan, Alexander D. Lemenze, Amariliz Rivera, Amariliz Rivera, Tibor Rohacs, Mark C. Siracusa, Mark C. Siracusa   +23 more
doaj   +2 more sources

Interleukin-4 and its receptor alpha in paediatric uncomplicated malaria patients from a Ghanaian case-control study [PDF]

BMC Research Notes
Objectives This study investigated gene polymorphisms in the interleukin-4 (IL-4) and its receptor alpha (IL-4Rα) gene regions in human hosts with uncomplicated malaria.
Patrick Diaba-Nuhoho
doaj   +2 more sources

Association of interleukin 4 (-590 T/C) and interleukin 4 receptor (Q551R A/G) gene polymorphisms with acne vulgaris

Annals of Saudi Medicine, 2012
BACKGROUND AND OBJECTIVES: Acne vulgaris is a common skin disorder. The complete etiology of this disease remains to be identified; however, it seems that aberrant expression of cytokine genes might be a contributing factor.
Ahmad A. Al Robaee, Abdullateef AlZolibani, Hani Al Shobaili, Ahmad Settin   +3 more
doaj   +1 more source

Reprogramming of lysosomal gene expression by interleukin-4 and Stat6. [PDF]

, 2013
BACKGROUND: Lysosomes play important roles in multiple aspects of physiology, but the problem of how the transcription of lysosomal genes is coordinated remains incompletely understood.
Bartlett, NW, Brignull, LM, Czimmerer, Z, Daniel, B, Johnston, SL, Meira, LB, Nagy, L, Nohturfft, A, Saidi, H, Villela, I   +9 more
core   +2 more sources

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha

Journal of Experimental Medicine, 1994
Using granulocyte/macrophage colony-stimulating factor (GM-CSF) and interleukin 4 we have established dendritic cell (DC) lines from blood mononuclear cells that maintain the antigen capturing and processing capacity characteristic of immature dendritic ...
F. Sallusto, A. Lanzavecchia
semanticscholar   +1 more source

possible protective role of interleukin-4 in rheumatoid arthritis

مجلة كلية الطب, 2005
Background:
khalidda Al- Mousawy, Al-haidary B A
doaj   +1 more source

Interleukin‐4 and interleukin‐13 evoke scratching behaviour in mice

Experimental Dermatology, 2019
Persistent and relapsing itch commonly manifests in inflammatory skin disorders such as atopic dermatitis (AD). AD pathogenesis is driven by interleukin‐4 (IL‐4) and interleukin‐13 (IL‐13). Dupilumab, a monoclonal antibody blocking the action of IL‐4 and
M. Campion, Leila Smith, S. Gatault, Charles Métais, J. Buddenkotte, M. Steinhoff   +5 more
semanticscholar   +1 more source

Interleukin-4 affects microglial autophagic flux

Neural Regeneration Research, 2019
Interleukin-4 plays an important protective role in Alzheimer’s disease by regulating microglial phenotype, phagocytosis of amyloid-β, and secretion of anti-inflammatory and neurotrophic cytokines.
Runhong Tang, Rui-Qun Qi, Hua-Yan Liu
semanticscholar   +1 more source

Correlations between Serum Interleukins-2,-4 Levels and Some Biochemical Parameters in Iraqi Patients with Osteoporosis

مجلة كلية الطب, 2017
Background: Osteoporosis is a frequent disease that is manifested by reduced in mineral density and raised in fracture risk. Recent studies have indicated that osteoporosis is caused by composite connections among local and systemic regulators of bone ...
Hind Sh. Ahmed
doaj   +1 more source

Differences in Expression of Selected Interleukins in HIV-Infected Subjects Undergoing Antiretroviral Therapy

Viruses, 2022
The use of combined antiretroviral therapy (cART) inhibits the replication of the Human Immunodeficiency Virus (HIV) and thus may affect the functioning of the immune system, e.g., induce changes in the expression of certain cytokines.
Beata Szymańska, Karolina Jurkowska, Brygida Knysz, Agnieszka Piwowar   +3 more
doaj   +1 more source