Results 21 to 30 of about 13,619,962 (300)

IL-4 and IL-13 Receptor Signaling From 4PS to Insulin Receptor Substrate 2: There and Back Again, a Historical View

Frontiers in Immunology, 2018
In this historical perspective, written in honor of Dr. William E. Paul, we describe the initial discovery of one of the dominant substrates for tyrosine phosphorylation stimulated by IL-4.
Achsah D. Keegan, Achsah D. Keegan, Jose Zamorano, Aleksander Keselman, Nicola M. Heller   +4 more
doaj   +1 more source

Scientific reports concerning the impact of interleukin 4, interleukin 10 and transforming growth factor  on cancer cells

Central European Journal of Immunology, 2019
Cytokines are signalling proteins generated in most part by immune cells that have critical functions in cellular lifespan. Here we present recent data on three selected anti-inflammatory cytokines: interleukin (IL)-10, IL-4 and transforming growth ...
Konrad Kwaśniak, Justyna Czarnik-Kwaśniak, Aleksandra Maziarz, David Aebisher, Kinga Zielińska, Bożenna Karczmarek-Borowska, Jacek Tabarkiewicz   +6 more
doaj   +1 more source

In search of biomarkers for low back pain: can traction therapy effectiveness be prognosed by surface electromyography or blood parameters?

Frontiers in Physiology, 2023
Background: Lumbar traction therapy is a common method to reduce low back pain (LBP) but is not always effective. The search for biomarkers that would prognose the effectiveness of LBP management is one priority for improving patients’ quality of life ...
Marzena Ratajczak, Małgorzata Waszak, Ewa Śliwicka, Michał Wendt, Damian Skrypnik, Jacek Zieliński, Piotr Krutki   +6 more
doaj   +1 more source

Interleukin-1 regulates multiple atherogenic mechanisms in response to fat feeding [PDF]

, 2009
Background: Atherosclerosis is an inflammatory process that develops in individuals with known risk factors that include hypertension and hyperlipidaemia, influenced by diet.
Dower, S., Zoe Brookes, Nicholas J Alp, Francis, Sheila, Steven Dower, David C Crossman, Brookes, Zoe, Francis, S., Shaw, Gary, Shaw, G., Crossman, D.C., Gary Shaw, Sheila Francis, Graham, Delyth, Brookes, Z., Alp, N.J., Crossman, David C., Chamberlain, J., Delyth Graham, Dower, Steven, Graham, D., Xu, A., Janet Chamberlain, Alp, Nicholas J., Xu, Aimin, Chamberlain, Janet   +25 more
core   +1 more source

Wikstroemiaganpi Extract Improved Atopic Dermatitis-Like Skin Lesions via Suppression of Interleukin-4 in 2,4-Dinitrochlorobenzene-Induced SKH-1 Hairless Mice

Molecules, 2021
Plants of the genus Wikstroemia are used in Chinese traditional medicine to treat inflammatory diseases, such as arthritis, bronchitis, and pneumonia. The present study was designed to determine whether Wikstroemia ganpi (Siebold and Zucc.) Maxim. offers
Jonghwan Jegal, No-June Park, Beom-Geun Jo, Tae-Young Kim, Sim-Kyu Bong, Sangho Choi, Jin-Hyub Paik, Jung-Won Kim, Su-Nam Kim, Min Hye Yang   +9 more
doaj   +1 more source

Human mid-gestation amniotic fluid contains interleukin-16 bioactivity [PDF]

, 2009
CD4-positive cells are detectable in the human fetal gastrointestinal tract from 11 weeks of gestation. Interleukin-16 (IL-16) is a chemoattractant for CD4(+) cells and, via fetal swallowing of amniotic fluid, could mediate the influx of CD4(+) cells ...
Warner, J., John W. Holloway, Thornton, Catherine A., Diaper, Norma D., Holloway, John W., Diaper, N., Shute, Janis K., Warner, John O., Catherine A. Thornton, Janis K. Shute, John O. Warner, Holloway, J., Cathy Thornton, Holloway, Judith A., Shute, Jan, Norma D. Diaper, Thornton, C., Judith A. Holloway   +17 more
core   +1 more source

Content of Pro- and Anti-inflammatory Cytokines in Blood Serum of Children with Bronchial Asthma of Various Severity

Zdorovʹe Rebenka, 2012
The paper presents the findings of investigation of content of proinflammatory interleukin-1 and anti-inflammatory interleukin-4 in blood serum of children with asthma in the dynamics of disease and dependence of their level on severity of illness ...
O.I. Smiyan, V.O. Kurganska, O.P. Moshchych, P.I. Sichnenko, V.A. Gorbas   +4 more
doaj   +1 more source

Differential effects of age on chicken heterophil functional activation by recombinant chicken interleukin-2 [PDF]

, 2002
Interleukin-2 (IL-2) exercises an array of biological effects on many cells including the functional activation of cells of the innate immune response.
Pete Kaiser, Kogut, Michael, Michael Kogut, Kaiser, Pete, Lisa Rothwell, Rothwell, Lisa   +5 more
core   +1 more source

Reprogramming of lysosomal gene expression by interleukin-4 and Stat6. [PDF]

, 2013
BACKGROUND: Lysosomes play important roles in multiple aspects of physiology, but the problem of how the transcription of lysosomal genes is coordinated remains incompletely understood.
Meira, LB, Czimmerer, Z, Louise M Brignull, Hafida Saidi, Saidi, H, Bartlett, Nathan W., Bence Daniel, Nagy, László, Villela, Izabel, Nohturfft, A, Brignull, LM, Izabel Villela, Johnston, Sebastian L., Meira, Lisiane B., Villela, I, Axel Nohturfft, Nohturfft, Axel, Zsolt Czimmerer, Brignull, L. M., Nathan W Bartlett, Saidi, H., Dániel, Bence, Czimmerer, Zsolt, Daniel, B, Lisiane B Meira, Saidi, Hafida, Brignull, Louise M., Nagy, L, Villela, I., Laszlo Nagy, Bartlett, NW, Johnston, SL, Sebastian L Johnston   +32 more
core   +1 more source

IL-13R alpha 2 reverses the effects of IL-13 and IL-4 on bronchial reactivity and acetylcholine-induced Ca2+ signaling [PDF]

, 2007
Background: The interleukins IL-4 and IL-13 play a key role in the pathophysiology of asthma. The interleukin receptor IL-13R alpha 2 is believed to act as a decoy receptor, but until now, the functional significance of IL-13R alpha 2 remains vague ...
Kellner, Julia, Welsch, Ulrich, Joerres, Rudolf A., Bergner, Albrecht, Gamarra, Fernando, Huber, Rudolf M., Jörres, Rudolf A.   +6 more
core   +1 more source