Results 11 to 20 of about 705,101 (300)

The immunosuppressive cytokine interleukin-4 increases the clonogenic potential of prostate stem-like cells by activation of STAT6 signalling [PDF]

, 2017
Interleukin-4 plays a critical role in the regulation of immune responses and has been detected at high levels in the tumour microenvironment of cancer patients, where concentrations correlate with the grade of malignancy. In prostate cancer, interleukin-
A Heidenreich, A Heidenreich, A Hobisch, A Laine, AT Collins, AT Collins, BA Smith, BH Li, C Conticello, D Vyas, DL Vaux, ES Polson, FL Koller, FM Di Maggio, FM Frame, FM Frame, FR Santer, GD Richardson, GJ Wise, H Ishiguro, H Jiang, H Korkaya, H Roca, HH Erb, J Ohara, JK Rane, JK Rane, JW Lowenthal, K Nelms, KT Venmar, LA Torre, M Puhr, M Todaro, N Hail Jr, N Wang, NA Franken, NJ Maitland, O Prokopchuk, P Kroon, PA Kupelian, R Goldstein, R Sigl, RA Seder, RA Taylor, RH Kutner, S Das, S Detre, S Michael, S Nagashima, S Ostrand-Rosenberg, SA Mani, SA Stewart, SH Lang, SM Crusz, SO Lee, SO Lee, SO Lee, SR Husain, U Takeshi, VS Jones, WM Ciszewski, Y Chiba, Y Chiba, Z Culig, Z Culig, Z Ni   +65 more
core   +2 more sources

possible protective role of interleukin-4 in rheumatoid arthritis

مجلة كلية الطب, 2005
Background:
khalidda Al- Mousawy, Al-haidary B A
doaj   +1 more source

Decreased Interleukin-4 Release from the Neurons of the Locus Coeruleus in Response to Immobilization Stress [PDF]

, 2016
It has been demonstrated that immobilization (IMO) stress affects neuroimmune systems followed by alterations of physiology and behavior. Interleukin-4 (IL-4), an anti-inflammatory cytokine, is known to regulate inflammation caused by immune challenge ...
An, Kyungeh, Lee, Hyun-ju, Park, Hyun-Jung, Shim, Insop, Starkweather, Angela   +4 more
core   +4 more sources

New and emerging therapeutic options for malignant pleural mesothelioma: review of early clinical trials. [PDF]

, 2015
Malignant pleural mesothelioma (MPM) is a rare tumor that is challenging to control. Despite some benefit from using the multimodality-approach (surgery, combination chemotherapy and radiation), survival remains poor. However, current research produced a
Cameron, Robert B, Kotova, Svetlana, Wong, Raymond M   +2 more
core   +2 more sources

Correlations between Serum Interleukins-2,-4 Levels and Some Biochemical Parameters in Iraqi Patients with Osteoporosis

مجلة كلية الطب, 2017
Background: Osteoporosis is a frequent disease that is manifested by reduced in mineral density and raised in fracture risk. Recent studies have indicated that osteoporosis is caused by composite connections among local and systemic regulators of bone ...
Hind Sh. Ahmed
doaj   +1 more source

Differences in Expression of Selected Interleukins in HIV-Infected Subjects Undergoing Antiretroviral Therapy

Viruses, 2022
The use of combined antiretroviral therapy (cART) inhibits the replication of the Human Immunodeficiency Virus (HIV) and thus may affect the functioning of the immune system, e.g., induce changes in the expression of certain cytokines.
Beata Szymańska, Karolina Jurkowska, Brygida Knysz, Agnieszka Piwowar   +3 more
doaj   +1 more source

Signaling via interleukin-4, receptor alpha chain is required for successful vaccination against schistosomiasis in BALB/c mice [PDF]

, 2001
Radiation-attenuated (RA) schistosome larvae are potent stimulators of innate immune responses at the skin site of exposure (pinna) that are likely to be important factors in the development of Th1-mediated protective immunity.
Anderson S., Anderson S., Anderson S., Artis D., Bancroft A. J., Bancroft A. J., Barner M., Belkaid Y., Brewer J. M., Brombacher F., Coulson P. S., D'Andrea A., de Andres B., Dean D. A., Delgado V., Donaldson D. D., Faquim-Mauro E. L., Galbiati F., Grunig G., Guler M. L., Hilton D. J., Hoffmann K. F., Hsieh C. S., James S. L., Jankovic D., Jankovic D., Jankovic D., King C. L., King C. L., Kopf M., Magram J., Mangold B. L., Matthews D. J., Mattner F., McKenzie G. J., Metwali A., Mohrs M., Mohrs M., Mountford A. P., Mountford A. P., Mountford A. P., Mountford A. P., Mountford A. P., Mountford A. P., Muchamuel T., Nelms K., Noben-Trauth N., Noben-Trauth N., Noben-Trauth N., O'Garra A., Pearce E. J., Reiner S. L., Scott P., Seder R. A., Sher A., Shibuya K., Smythies L. E., Smythies L. E., Street M., Szabo S. J., Urban J. F., Wilson R. A., Wynn T. A., Wynn T. A., Zurawski G.   +64 more
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The Regulatory Effects of Interleukin-4 Receptor Signaling on Neutrophils in Type 2 Immune Responses

Frontiers in Immunology, 2019
Interleukin-4 (IL-4) receptor (IL-4R) signaling plays a pivotal role in type 2 immune responses. Type 2 immunity ensures several host-protective processes such as defense against helminth parasites and wound repair, however, type 2 immune responses also ...
Cecilie Egholm, Lukas E. M. Heeb, Daniela Impellizzieri, Onur Boyman, Onur Boyman   +4 more
doaj   +1 more source

Concentrations of matrix metallopeptidase 9, interleukin 4, and interleukin 8 in follicular fluid, and the results of fertilization

Journal of International Medical Research, 2022
Objective Cytokines and enzymes in follicular fluid (FF) may have a crucial role in fertility. This study aimed to analyse the results of in vitro fertilization/embryo transfer (IVF/ET) and compare them with matrix metalloproteinase 9 (MMP-9) and ...
Rafał Adamczak, Natalia Ukleja-Sokołowska, Kinga Lis, Zbigniew Bartuzi, Mariusz Dubiel   +4 more
doaj   +1 more source

Class-switched anti-insulin antibodies originate from unconventional antigen presentation in multiple lymphoid sites [PDF]

, 2016
Autoantibodies to insulin are a harbinger of autoimmunity in type 1 diabetes in humans and in non-obese diabetic mice. To understand the genesis of these autoantibodies, we investigated the interactions of insulin-specific T and B lymphocytes using T ...
Acevedo-Suárez, Achenbach, Adelstein, Akashi, Batista, Bodansky, Cooke, Crotty, Dean, Emil R. Unanue, Ferris, Gagnerault, Garside, Gitlin, Glazier, Goodnow, Greeley, Gretz, Harbers, Henry, Henry, Henry-Bonami, Hoppu, Hu, Hulbert, Höglund, James W. Thomas, Kendall, Kendall, Kenefeck, Levisetti, Linterman, Mariño, Mohan, Mohan, Mohan, Nakayama, Noorchashm, Okada, Pape, Rasio, Reinhardt, Rojas, Roozendaal, Serreze, Silva, Takahashi, Ueno, Unanue, Victora, Victora, Vinuesa, Vomund, Williams, Xiaoxiao Wan, Yang, Zhang, Zhang, Zikherman, Zotos   +59 more
core   +2 more sources