Results 11 to 20 of about 12,582,645 (332)
possible protective role of interleukin-4 in rheumatoid arthritis
مجلة كلية الطب, 2005 Background:
khalidda Al- Mousawy, Al-haidary B A
doaj +1 more source
Interleukin‐4 and interleukin‐13 evoke scratching behaviour in mice
Experimental Dermatology, 2019 Persistent and relapsing itch commonly manifests in inflammatory skin disorders such as atopic dermatitis (AD). AD pathogenesis is driven by interleukin‐4 (IL‐4) and interleukin‐13 (IL‐13). Dupilumab, a monoclonal antibody blocking the action of IL‐4 and
M. Campion +5 more
semanticscholar +1 more source
Interleukin-4 affects microglial autophagic flux
Neural Regeneration Research, 2019 Interleukin-4 plays an important protective role in Alzheimer’s disease by regulating microglial phenotype, phagocytosis of amyloid-β, and secretion of anti-inflammatory and neurotrophic cytokines.
Runhong Tang, Rui-Qun Qi, Hua-Yan Liu
semanticscholar +1 more source
مجلة كلية الطب, 2017 Background: Osteoporosis is a frequent disease that is manifested by reduced in mineral density and raised in fracture risk. Recent studies have indicated that osteoporosis is caused by composite connections among local and systemic regulators of bone ...
Hind Sh. Ahmed
doaj +1 more source
Viruses, 2022 The use of combined antiretroviral therapy (cART) inhibits the replication of the Human Immunodeficiency Virus (HIV) and thus may affect the functioning of the immune system, e.g., induce changes in the expression of certain cytokines.
Beata Szymańska +3 more
doaj +1 more source
Journal of Experimental Medicine, 1992 Expression of the macrophage mannose receptor is inhibited by interferon gamma (IFN-gamma), a T helper type 1 (Th-1)-derived lymphokine. Interleukin 4 (IL-4), a Th-2 lymphocyte product, upregulates major histocompatibility class II antigen expression but
M. Stein +3 more
semanticscholar +1 more source
The Regulatory Effects of Interleukin-4 Receptor Signaling on Neutrophils in Type 2 Immune Responses
Frontiers in Immunology, 2019 Interleukin-4 (IL-4) receptor (IL-4R) signaling plays a pivotal role in type 2 immune responses. Type 2 immunity ensures several host-protective processes such as defense against helminth parasites and wound repair, however, type 2 immune responses also ...
Cecilie Egholm +4 more
doaj +1 more source
Drug Safety, 2018 IntroductionInterleukin-13 and interleukin-4 are type-II cytokines signalling through the shared type II interleukin-4 receptor. As a result of their structural similarity, interleukin-13 and interleukin-4 have overlapping functions in the mediation of ...
M. Braddock +4 more
semanticscholar +1 more source
Journal of International Medical Research, 2022 Objective Cytokines and enzymes in follicular fluid (FF) may have a crucial role in fertility. This study aimed to analyse the results of in vitro fertilization/embryo transfer (IVF/ET) and compare them with matrix metalloproteinase 9 (MMP-9) and ...
Rafał Adamczak +4 more
doaj +1 more source
Memorias do Instituto Oswaldo Cruz, 1997 Clinical and experimental investigations suggest that allergen-specific CD4+ T-cells, IgE and the cytokines IL-4 and IL-5 play central roles in initiating and sustaining an asthmatic response by regulating the recruitment and/or activation of airways ...
Paul S Foster +3 more
doaj +1 more source