Results 91 to 100 of about 719,716 (198)

Interleukin-4 receptor pathway in neurons

, 2018
Multiple sclerosis (MS) is a chronic demyelinating inflammatory disease of the central nervous system (CNS) and belongs to the most frequent causes of irreversible disability in younger people. During the disease course of MS and the corresponding animal model experimental autoimmune encephalomyelitis (EAE), both adaptive and innate immune cells ...
openaire   +3 more sources

Anti-interleukin 4 receptor α antibody for the treatment of Chinese bullous pemphigoid patients with diverse comorbidities and a 1-year follow-up: a monocentric real-world study. [PDF]

Front Immunol, 2023
Wang SH, Shan Y, Li SZ, Zuo YG.
europepmc   +1 more source

Interleukin-4 (IL-4) enhances and soluble interleukin-4 receptor (sIL-4R) inhibits histamine release from peripheral blood basophils and mast cells in vitro and in vivo

Mediators of Inflammation, 1997
The aim of the study was to analyse the effect of interleukin-4 (IL-4) on allergen and anti-IgE mediated histamine release from basophils and human skin mast cells and to assess whether soluble recombinant interleukin-4 receptor (sIL4R) can inhibit these
B. Niggemann, T. Zuberbier, U. Herz, K. Enssle, U. Wahn, H. Renz   +5 more
doaj   +1 more source

Genetic Polymorphism of Toll-like Receptor 4 — Predictor of Susceptibility to Recurrent Course of Chronic Pyelonephritis in Children

Zdorovʹe Rebenka, 2013
Objective of investigation: to study the role of Toll-like receptor 4 Asp299Gly gene polymorphism in the implementation of susceptibility to chronic pyelonephritis, to analyze its association with the major manifestations of the disease and to assess the
T.A. Kryuchko, V.P. Ostapenko, T.V. Kushnereva   +2 more
doaj   +1 more source

Tetracyclines improve experimental lymphatic filariasis pathology by disrupting interleukin-4 receptor-mediated lymphangiogenesis. [PDF]

J Clin Invest, 2021
Furlong-Silva J, Cross SD, Marriott AE, Pionnier N, Archer J, Steven A, Merker SS, Mack M, Hong YK, Taylor MJ, Turner JD.   +10 more
europepmc   +1 more source

Detection of R576 interleukin-4 receptor αn allele gene, serum interleukin-4, and eosinophilic cationic protein in atopic dermatitis patients

Indian Journal of Dermatology, 2009
Atopic dermatitis (AD) is a chronic pruritic skin disease. It results from a complex interplay between strong genetic and environmental factors. The aim of this work was to study some biochemical markers of the dermatosis. This included detection of R576
Abdel-Mawla M, Mostafa Y, Abuel-Majd Y, Attwa Rasha   +3 more
doaj  

Peculiarities of CD4+ cell signaling in asthma patients exposed to suspended solid particles of atmospheric air

Russian Open Medical Journal
Objective — To evaluate the expression of receptors for interleukin-4 (IL-4R), 6 (IL-6R), toll-like receptors 2 (TLR2) and 4 (TLR4) of T helper (Th) cells (CD4+), as well as the content of interleukin-4 (IL-4) and 6 (IL-6) in the blood serum of patients ...
Tatyana I. Vitkina, Elena V. Kondratyeva, Tatyana A. Gvozdenko   +2 more
doaj   +1 more source

Th2 cytokines and asthma — Interleukin-4: its role in the pathogenesis of asthma, and targeting it for asthma treatment with interleukin-4 receptor antagonists

Respiratory Research, 2001
Interleukin-4 (IL-4) mediates important pro-inflammatory functions in asthma including induction of the IgE isotype switch, expression of vascular cell adhesion molecule-1 (VCAM-1), promotion of eosinophil transmigration across endothelium, mucus ...
Borish Larry, Steinke John W
doaj   +1 more source

Multiparametric MRI assessment of response to convection-enhanced intratumoral delivery of MDNA55, an interleukin-4 receptor targeted immunotherapy, for recurrent glioblastoma. [PDF]

Surg Neurol Int, 2021
Mohan S, Wang S, Chawla S, Abdullah K, Desai A, Maloney E, Brem S.   +6 more
europepmc   +1 more source

Interleukin-4 receptor −3223C→T Polymorphism is Associated with Increased Gastric Adenocarcinoma Risk

Canadian Journal of Gastroenterology, 2012
BACKGROUND: Gastric cancer remains one of the most common types of cancer worldwide, with a large geographical variation in incidence and mortality rates. Cytokine polymorphisms are the most studied host polymorphisms and are associated with an increased
Florin Burada, Cristina Angelescu, Paul Mitrut, Tudorel Ciurea, Mihai Cruce, Adrian Saftoiu, Mihai Ioana   +6 more
doaj   +1 more source