Interleukin 6: friend or foe in diabetic nephropathy? [PDF]
Archives of Medical ScienceIntroduction This study aimed to investigate the relationship between serum cytokine levels, particularly interleukin 6 (IL-6), and diabetic nephropathy (DN) in patients with type 1 (T1D) and type 2 diabetes (T2D). Material and methods A cross-sectional
Renad M. Alhamawi +2 more
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Giant Cell Arteritis Refractory to Interleukin‐6 and Interleukin‐17 Inhibition Treated With Upadacitinib [PDF]
ACR Open RheumatologyGiant cell arteritis (GCA) is a granulomatous vasculitis that can involve both cranial and extracranial vessels. Although interleukin‐6 (IL‐6) receptor blockade is an established therapy, treatment options for medically refractory disease remain limited.
Luke S. Vest +4 more
doaj +2 more sources
P-769. Utility of Urinary Interleukin-6 to aid in the Diagnosis and to assess Prognosis in Urinary Tract Infections [PDF]
Open Forum Infect DisAnupam Dey +4 more
europepmc +2 more sources
Interleukin 6 in aging and age-related diseases
Klinicist, 2021 Modern concepts about the importance of subclinical inflammation in various age-associated pathology are described in the review. The term “inflammaging” (inflammation due to aging) refers to the special role of inflammation in the aging processes.
S. V. Topolyanskaya
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Interleukin-6 Promoter Haplotypes and Interleukin-6 Cytokine Responses [PDF]
Shock, 2003 Genetic variations contribute to differences in the inflammatory response and are markers for disease risk and outcomes. We studied three single-nucleotide polymorphisms (-597 G-->A, -572 G-->C, and -174 G-->C) in the IL-6 promoter to determine associations with ex vivo LPS-stimulated IL-6 production by leukocytes.
Fernando A, Rivera-Chavez +3 more
openaire +2 more sources
Interleukin 6 in aging and age-related diseases
Klinicist, 2020 Modern concepts about the importance of subclinical inflammation in various age-associated pathology are described in the review. The term “inflammaging” (inflammation due to aging) refers to the special role of inflammation in the aging processes.
S. V. Topolyanskaya
doaj +1 more source
Sepsis induces interleukin 6, gp130/JAK2/STAT3, and muscle wasting
Journal of Cachexia, Sarcopenia and Muscle, 2022 Background Sepsis and inflammation can cause intensive care unit‐acquired weakness (ICUAW). Increased interleukin‐6 (IL‐6) plasma levels are a risk factor for ICUAW. IL‐6 signalling involves the glycoprotein 130 (gp130) receptor and the JAK/STAT‐pathway,
Lukas Zanders +13 more
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P-65. Clinical and microbiological characteristics of bacteremia in anti-interleukin-6 inhibitor recipients [PDF]
Open Forum Infect DisKoh Shinohara +5 more
europepmc +2 more sources
Correlation Between Interleukin 6 and Interleukin 10 in Acute Myocardial Infarction
Biomolecules & Biomedicine, 2009 The aim of this study was to analyze (i) ratios between pro-inflammatory cytokines interleukin 6 (IL-6), interleukin 1 (IL-1), tumour necrosis factor α (TNF-α) and anti-inflammatory cytokine interleukin 10 (IL-10) in patients with acute myocardial ...
Larisa Dizdarević-Hudić +9 more
doaj +1 more source
Detection of Salivary Interleukin 2 and Interleukin 6 in Patients With Burning Mouth Syndrome
Mediators of Inflammation, 2006 The etiology of BMS remains unknown. Role of various cytokines has been implicated in the development of BMS. The aim of this study was to evaluate levels of salivary IL-2 and IL-6 in patients with BMS, compared with age-matched healthy volunteers ...
Daria Simcic +5 more
doaj +2 more sources