Results 1 to 10 of about 9,333,661 (382)
Interleukin 6: friend or foe in diabetic nephropathy? [PDF]
Archives of Medical ScienceIntroduction This study aimed to investigate the relationship between serum cytokine levels, particularly interleukin 6 (IL-6), and diabetic nephropathy (DN) in patients with type 1 (T1D) and type 2 diabetes (T2D). Material and methods A cross-sectional
Renad M. Alhamawi +2 more
doaj +2 more sources
Interleukin-6 Signaling and Anti-Interleukin-6 Therapeutics in Cardiovascular Disease
Circulation Research, 2021 IL (interleukin)-6 is a pivotal cytokine of innate immunity, which enacts a broad set of physiological functions traditionally associated with host defense, immune cell regulation, proliferation, and differentiation.
P. Ridker, Manas Rane
semanticscholar +3 more sources
Interleukin-6 in Rheumatoid Arthritis [PDF]
International Journal of Molecular Sciences, 2020 The role of interleukin (IL)-6 in health and disease has been under a lot of scrutiny in recent years, particularly during the recent COVID-19 pandemic.
Pandolfi Franco +5 more
semanticscholar +5 more sources
Giant Cell Arteritis Refractory to Interleukin‐6 and Interleukin‐17 Inhibition Treated With Upadacitinib [PDF]
ACR Open RheumatologyGiant cell arteritis (GCA) is a granulomatous vasculitis that can involve both cranial and extracranial vessels. Although interleukin‐6 (IL‐6) receptor blockade is an established therapy, treatment options for medically refractory disease remain limited.
Luke S. Vest +4 more
doaj +2 more sources
Expression of interleukin 1-alpha, interleukin 6 and CD 10 in predicting recurrence of ameloblastoma [PDF]
Discover OncologyPurpose Ameloblastoma (AM) is a clinically significant odontogenic tumour known for its local invasive and high post-treatment recurrence risk. Despite advancements in surgical techniques, predicting recurrence remains challenging.
Nurhazwani Mohd Danil +3 more
doaj +2 more sources
The Role of Interleukin 6 During Viral Infections
Frontiers in Microbiology, 2019 Lauro Velazquez-Salinas +4 more
doaj +2 more sources
Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19
medRxiv, 2021 Background: The efficacy of interleukin-6 receptor antagonists in critically ill patients with coronavirus disease 2019 (Covid-19) is unclear. Methods: We evaluated tocilizumab and sarilumab in an ongoing international, multifactorial, adaptive platform ...
A. Gordon +61 more
semanticscholar +1 more source
Interleukin 6 in aging and age-related diseases
Klinicist, 2021 Modern concepts about the importance of subclinical inflammation in various age-associated pathology are described in the review. The term “inflammaging” (inflammation due to aging) refers to the special role of inflammation in the aging processes.
S. V. Topolyanskaya
doaj +1 more source
Interleukin 6: at the interface of human health and disease
Frontiers in Immunology, 2023 Interleukin 6 (IL-6) is a pleiotropic cytokine executing a diverse number of functions, ranging from its effects on acute phase reactant pathways, B and T lymphocytes, blood brain barrier permeability, synovial inflammation, hematopoiesis, and embryonic ...
Elena Grebenciucova, Stephen VanHaerents
semanticscholar +1 more source
Interleukin-6 and intrapulmonary shunt [PDF]
European Respiratory Journal, 2021 Based on animal studies and indirect clinical evidence, it may be speculated that IL-6 has a pathophysiological role in intrapulmonary shunt associated to COVID-19 https://bit.ly ...
Pérez Vizcaíno, Francisco +2 more
openaire +6 more sources