Inflammatory Markers Associated With Subclinical Coronary Artery Disease: The Multicenter AIDS Cohort Study. [PDF]
, 2016 BackgroundDespite evidence for higher risk of coronary artery disease among HIV+ individuals, the underlying mechanisms are not well understood. We investigated associations of inflammatory markers with subclinical coronary artery disease in 923 ...
Bahrami, Hossein +10 more
core +2 more sources
Elevated interleukin‐6 and severe COVID‐19: A meta‐analysis
Journal of Medical Virology, 2020 Interleukin-6 is an important marker of inflammation. We performed a systematic review and meta-analysis to demonstrate the association of elevated IL-6 with severe Coronavirus disease-2019 (COVID-19). A total of 9 studies were included in the systematic
Muhammad Aziz, Rawish Fatima, R. Assaly
semanticscholar +1 more source
Prognostic value of interleukin-6, C-reactive protein, and procalcitonin in patients with COVID-19
Journal of Clinical Virology, 2020 Highlights • The serum levels of IL-6 and CRP have a significant correlation with the severity of COVID-19.• The serum levels of IL-6 and CRP can be used as independent factors to predict disease risk.• The validity of PTC needs to be further ...
Fang Liu +8 more
semanticscholar +1 more source
Increased levels of interleukin-6 exacerbate the dystrophic phenotype in mdx mice [PDF]
, 2015 Duchenne muscular dystrophy (DMD) is characterized by progressive lethal muscle degeneration and chronic inflammatory response. The mdx mouse strain has served as the animal model for human DMD. However, while DMD patients undergo extensive necrosis, the
Berardinelli, Maria Grazia +10 more
core +2 more sources
Early-life adversity accelerates cellular ageing and affects adult inflammation: experimental evidence from the European starling [PDF]
, 2017 Early-life adversity is associated with accelerated cellular ageing during development and increased inflammation during adulthood. However, human studies can only establish correlation, not causation, and existing experimental animal approaches alter ...
Andrews, Clare +8 more
core +4 more sources
The role of interleukin‐6 in monitoring severe case of coronavirus disease 2019
EMBO Molecular Medicine, 2020 Progression to severe disease is a difficult problem in treating coronavirus disease 2019 (COVID‐19). The purpose of this study is to explore changes in markers of severe disease in COVID‐19 patients.
Tao Liu +12 more
semanticscholar +1 more source
Validation of an automated enzyme immunoassay for interleukin-6 for routine clinical use [PDF]
, 1998 Serum levels of Interleukin-6 (IL-6), a proinflammatory cytokine, are increased in early stages of inflammatory diseases such as infection and sepsis. Assay systems which permit its measurement within a few hours and as a single measurement have not been
Cremer, Peter +8 more
core +1 more source
Regulation of adipose tissue inflammation by interleukin 6
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance Chronic low-grade inflammation is a key driver of metabolic syndrome. This inflammatory response is mediated by immune-cell infiltration and the expression of inflammatory cytokines.
M. Han +6 more
semanticscholar +1 more source
Historical overview of the interleukin-6 family cytokine
Journal of Experimental Medicine, 2020 Kishimoto and colleagues present an overview of the complex biology of interleukin-6 family cytokines, focusing on signaling transduction of the receptor molecule.
Sujin Kang +3 more
semanticscholar +1 more source
Role of Interleukin-6 in Depressive Disorder
International Journal of Molecular Sciences, 2020 Major depressive disorder (MDD), which is a leading psychiatric illness across the world, severely affects quality of life and causes an increased incidence of suicide.
E. Y. Ting, A. Yang, S. Tsai
semanticscholar +1 more source